Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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High Capacity RNA-to-cDNA Kit

Thermo Fisher Scientific

High Capacity RNA-to-cDNA Kit is a streamlined reverse transcription kit designed for optimum performance with the TaqMan® Gene Expression Master Mix, Power SYBR® Green PCR Master Mix and others. The components of the two-tube kit work together to provide sensitive and specific reverse transcription across a broad range of template quantities. The new High Capacity RNA-to-cDNA formulation reduces reverse transcription time by…

4.3/5.0
|1 Review

SciFinder - Online Scientific Literature Search

Chemical Abstracts Service (CAS)

CAS SciFinder -  The First Choice With SciFinder from CAS, you can increase your productivity and achieve faster breakthroughs Advancing the pace of research, Chemical Abstracts SciFinder search allows you to get results fast without compromising precision and accuracy. CAS SciFinder allows you to explore a wealth of information using sophisticated search and analysis technology. Chemical Abstracts SciFinder is a research d…

4.0/5.0
|3 Reviews

TaqMan® MicroRNA Arrays

Thermo Fisher Scientific

TaqMan®  MicroRNA Arrays provide all the advantages of TaqMan®  MicroRNA Assays in a convenient, pre-configured micro fluidic card minimizing experimental variability and effort required to run 384 TaqMan MicroRNA Assays in parallel. Megaplex™ RT Primers are highly multiplexed RT primers designed to convert up to 381 miRNAs to cDNA prior to real-time analysis, and simplify the TaqMan MicroRNA Array. When sensitivity is of th…

4.3/5.0
|3 Reviews

MiniStore™

Matrical, Inc.

The MiniStore keeps samples safe, organized, and accessible. The MiniStore sample management system is capable of storing and tracking thousands or even millions of samples, all in one space saving location. Enjoy quick retrieval of individual and/or bulk samples for processing, from a single trusted storage system. The MiniStore automated sample storage system accommodates a variety of sample types and formats. The MiniStore…

3.8/5.0
|2 Reviews

Human TNF-alpha/TNFSF1A Quantikine ELISA Kit

Bio-Techne

R&D Human TNF-alpha/TNFSF1A Quantikine ELISA Kit - Human TNF-alpha Immunoassay for the quantitative determination of human tumor necrosis factor alpha (TNF-alpha) concentrations in cell culture supernates, serum, and plasma. The R&D Quantikine Human TNF-alpha Immunoassay is a 3.5 - 4.5 hour solid phase ELISA. This assay employs the quantitative sandwich enzyme immunoassay technique. A monoclonal antibody specific for TNF-alph…

3.9/5.0
|2 Reviews

Caspase 3/7 Reagent Kit (100 tests)

Merck

The Guava® Caspase 3/7 and 8 Assays employ a FLICA (Fluorescent Labeled Inhibitor of Caspases) reagent that specifically identifies active caspase 3 and 7 molecules or caspase 8 molecules. Non-cytotoxic, cell permeant dyes elimiate lysis and permeabilization procedures. Each FLICA is comprised of three subunits: A caspase-specific amino acid inhibitor containing a recognition sequence for caspase 3/7 (DEVD) or caspase 8 (LETD)…

3.9/5.0
|2 Reviews

Mouse IL-6 Quantikine ELISA Kit

Bio-Techne

Mouse IL-6 R&D Quantikine ELISA Kit - Mouse IL-6 Immunoassay for the quantitative determination of mouse interleukin 6 (IL-6) concentrations in cell culture supernates, mouse serum, and plasma. The R&D Quantikine Mouse IL-6 ELSIA is a 4.5 hour solid-phase ELISA. This R&D Quantikine assay employs the quantitative sandwich enzyme immunoassay technique.R&D Systems Quantikine ELISA Kits are complete and ready-to-use. Features of…

4.0/5.0
|1 Review

Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit

Bio-Techne

R&D Mouse IL-1 beta/IL-1F2 Quantikine ELISA Kit - R&D Mouse IL-1/IL-1F2 Immunoassay for the quantitative determination of mouse interleukin 1 beta (IL-1ß) concentrations in cell culture supernates and mouse serum. The R&D Quantikine Mouse IL-1 Immunoassay is a 4.5 hour solid phase ELISA. This R&D Quantikine assay employs the quantitative sandwich enzyme immunoassay technique. Features of the R&D Quantikine ELISA Kit inclu…

4.0/5.0
|1 Review

Yeast Two-Hybrid Systems

Takara Bio

More than 18,000 studies have been published citing the use of the yeast two-hybrid system to investigate protein-protein interactions, and Clontech’s Matchmaker™ Systems have been by far the most popular. Matchmaker™ Gold Systems are the highest performing incarnations of our Matchmaker product line, due to a combination of a new yeast strain (Y2HGold), stringent reporters, easy to use libraries, high-level expression vectors…

4.0/5.0
|1 Review

G-LISA™ Small G-protein Activation Assays

Cytoskeleton Inc.

The G-LISA™ assay uses a 96-well plate coated with RBD domain of Rho-family effector proteins. The active GTP-bound form of the Rho-family protein, but not the inactive GDP-bound form, from a biological sample will bind to the plate. Bound active Rho-family protein is then detected by incubation with a specific primary antibody followed by a secondary antibody conjugated to HRP. The signal is then developed with OPD or chemilu…

4.3/5.0
|1 Review

NL100 Nitrogen Laser

Stanford Research Systems Inc.

The NL100 Nitrogen Laser is ideal for fluorescence measurements, MALDI-TOF mass spectrometers, and other pulsed UV radiation experiments. It provides 3.5 ns pulses at 337 nm (UV), with repetition rates up to 20 Hz. The pulse energy is 170 µJ, which results in a peak power of 45 kW and an average power of 3 mW. The NL100 can be triggered internally or externally at rates up to 20 Hz. It can also provide a sync output pulse (opt…

3.7/5.0
|1 Review

SNAP i.d. 2.0 System

Merck

The SNAP i.d. Protein Detection System revolutionizes the quality of your blots every time — in record time! Unlike conventional Western blotting, where diffusion is the primary means of reagent transport, the SNAP i.d. system applies a vacuum to actively drive reagents through the membrane. This novel method allows you to optimize your blotting conditions in record time for maximum results. The SNAP i.d. system minimizes over…

4.4/5.0
|14 Reviews

MICROLAB NIMBUS

Hamilton Company

The MICROLAB® NIMBUS is Hamilton Company's newest automated multi-channel pipetting platform, offering a high density deck layout in a body small enough to fit inside a laminar flow hood. The system utilizes the same highly accurate 96-channel pipetting head as Hamilton's STAR instruments, yet is designed for smaller throughput applications. The NIMBUS is ideal for: • Fast plate replications • Row-wise and column-wide serial d…

4.0/5.0
|3 Reviews

VECTASTAIN ABC Kit

Vector Laboratories Inc.

Each VECTASTAIN® ABC kit utilizes the same preformed Avidin: Biotinylated enzyme Complex (ABC) principle and all offer low backgrounds and an amplification of signal compared to conven-tional covalent conjugates. The high sensitivity reported for this technique likely resides in either the form or the number of active enzyme molecules associated with the complex and the rapid, irreversible interaction of the complex with bio…

4.4/5.0
|3 Reviews

LISSY

Zinsser Analytic GmbH

Sample preparation for a wide range of analysis types, sample dissolution, serial dilutions, reformatting steps and much more can be fully automated with Zinsser’s flexible liquid handling system, LISSY. LISSY is available in various standard configurations: from 90cm up to 200cm in length, from 1 up to 16 pipetting probes, with or without integrated gripper for moving plates, individual tubes or tools, etc. As with all Zinsse…

4.0/5.0
|1 Review

Fill-It Automated screw-cap cryovial filling system

TAP Biosystems

Fill-It - is an automated benchtop system for filling screw-cap cryovials. Fill-It is designed to help create cell banks of higher quality, consistency and viability. It combines proven decap / recap modules with aseptic liquid handling. Fill-It removes all screw caps simultaneously and then dispenses into multiple cryovials in parallel. Compatible with Corning, Greiner, Micronic, Matrix, Nalgene, Nunc and Sarstedt screw-cap c…

4.3/5.0
|1 Review

Thermo Scientific TSQ Quantum Ultra Triple Stage Quadrupole Mass Spectrometer

Thermo Fisher Scientific

The Thermo Scientific TSQ Quantum Ultra mass spectrometer provides ultimate productivity for bioanalytical analysis. Faster method development at the highest possible specificity is routinely achievable with the TSQ Quantum Ultra™ mass spectrometer. Featuring the patented Thermo Scientific HyperQuad quadrupole mass analyzer system, the TSQ Quantum Ultra performs highly selective reaction monitoring (H-SRM), which provides gr…

4.3/5.0
|10 Reviews


MeltDoctor™ HRM Master Mix

Thermo Fisher Scientific

High Resolution Melting (HRM) analysis is a post-PCR analysis method used to identify genetic variation in nucleic acid sequences. The MeltDoctor™ HRM Master Mix contains all components (excluding template and primers) formulated for superior HRM performance across a wide range of genomic targets. Unlike some competitive mixes, the MeltDoctor™ HRM Master Mix does not require additional mixing prior to use, and was developed…

4.0/5.0
|1 Review

MagNA Pure 96 System

The MagNA Pure 96 System from Roche Applied Science has been designed and engineered to meet the needs for high throughput laboratories worldwide. The integrated system enables batch processing of up to 96 samples in parallel ensuring every sample is treated exactly the same while providing extremely quick turnaround time. These characteristics result in a low sample processing time; for typical standard applications, 96 sampl…

4.0/5.0
|1 Review

Lightning-Link™ HRP kit

Innova Biosciences Ltd.

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…

4.3/5.0
|1 Review

Lightning-Link™ Glucose Oxidase (GOx) kit

Innova Biosciences Ltd.

Say goodbye to secondary antibodies – Go direct using the World’s Easiest DIY Antibody Labeling Kit - Lightning-Link™! • Eliminates need for secondary antibodies • Reduces the number of wash steps • Ideal for multi-protein analysis – with over 40 available labels • Very easy to use • 100% antibody recovery Lightning-Link™ kits The DIY Lightning-Link™ kit allows you to label an antibody with minimal hands-on time - less than 30…

4.3/5.0
|1 Review

Echo® 500 Series Liquid Handlers

The Echo® liquid handler revolutionizes liquid handling with acoustic energy. Sound waves eject precisely sized droplets from a source onto a microplate, slide or other surface suspended above the source. This product does not use tips, pin tools or nozzles—completely eliminating contact between the instrument and the liquid. The Echo liquid handler provides powerful benefits: Tipless transfer, resulting in dramatic cost s…

4.4/5.0
|82 Reviews

HyClone Fetal Bovine Serum

Hyclone Laboratories, Inc.

HyClone Fetal Bovine Serum - Thermo HyClone Fetal Bovine Serum, U.S. Origin is filtered through serial 40µm (0.04µm) pore-size rated filters. Eliminate concerns about viral contamination in Fetal Bovine Serum (FBS) without compromising cell culture performance. HyClone FBS is widely used by those culturists who require an extensive biochemical profile. Defined FBS is filtered through the most retentive filters used in commerci…

4.4/5.0
|3 Reviews

NimbleGen Gene Expression Microarray

Roche

Roche NimbleGen provides a unique combination of high-density arrays, long-oligo probes, and flexible design capability that together provide superior results for advanced gene expression analysis. NimbleGen microarrays enable accurate, sensitive, and specific interrogation of genome-wide expression for any sequenced and annotated genome. Researchers also can tile through a genome at any desired spacing to discover genome-wide…

4.0/5.0
|1 Review