Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
The Sigma lenti CRISPR Non-Targeting Control is a lentiviral plasmid vector, which includes a gRNA sequence that does not target known human, mouse and rat genes. This vector is useful as a negative control in experiments using Sigma CRISPR lentiviral clones.
Human CRISPRi Kinase Phosphatase Drug Targets Kit contains 2 sub-pools of top 5 gRNAs per gene as well as a separate sub-pool of 5 supplemental gRNAs per gene for increased sensitivity and includes non-targeting controls built in.
The Lenti CRISPR Non-Target Control#1 (LV04 vector) is a lentiviral plasmid vector, which includes a gRNA sequence that does not target known human, mouse and rat genes. The DNA format of this control construct permits direct transfection in knockout experiments or use in the viral packaging process (for lentiviral-based knockdown experiments).
The Sigma lenti CRISPR Non-Targeting Control is a lentiviral system, which includes a gRNA sequence that does not target known human, mouse and rat genes. The non-targeting control lentivirus is useful as a negative control in experiments using Sigma CRISPR lentiviral clones.
Pooled CRISPR screening with 10x genomics compatibility for discovery at single cell resolution
CYRIS monitors and analyzes several key cellular parameters in real-time and label-free. Cell viability, metabolism, and morphology can be screened in a fully automated and atmosphere-controlled environment. The incubator integrated solution measures oxygen, pH, and cellular impedance in a multiwell plate and makes through a digital inverse microscope phase-contrast like live-cell images.
The kit is designed to use with Agilent Seahorse XF Pro analyzer for easily identifying drug-induced mitochondrial toxicity, to de-risk your drug pipeline. It provides high sensitivity and specificity, reducing false positive and false negatives. It is applicable to screen compound libraries with a throughput of 80 compounds per plate. Assay performance metrics Z’ of > 0.5 is achievable following our assay workflow.
From picolitre to microliter, contact and non-contact dispensing technology combined in one highly automated production environment. The iZERO is M2-Automation`s ultra-fast, high-precision and fully flexible production line.
