Cell-Based Assays Products & Reviews

Insulin, a 5.8 kDa hormone is secreted by the islet beta cells in the pancreas. This kit offers sensitive assay for rat/mouse insulin

Leptin is synthesized in adipocytes as a 16 kDa molecule and the circulating level is directly proportional to the total amount of fat in the body.

Innova Biosciences, based on the Babraham Research Campus, Cambridge UK, has launched a family of assay reagents called PiColorLock™, to facilitate the measurement of the activity of phosphatases, ATPases and other Pi-generating enzymes in microplates. Unlike the traditional "Malachite Green" method, which is prone to precipitation problems, PiColorLock reagent is specially formulated to give a stable end-point signal, meani…

ColorKits are designed to facilitate the measurement of the activity of phosphatases, ATPases and other Pi-generating enzynes in microplate assays. Each Kit contains a phosphorylated substrate for a particular class of enzyme, together with a carefully optimised PiColorLock detection reagent, Pi standard, 2x96-well plates and a selection of buffer concentrates for optimisation of assay conditions with the enzyme of interest.…

PiColorLock Drug Discovery Kits are designed to facilitate the measurement of the activity of potential inhibitors of phosphatases, ATPases and other Pi-generating enzymes in microplates. The Kits combine a purified recombinant human enzyme target, phosphorylated substrate, Pi standard and 2 multiwell plates. Each Kit is also supplied with a carefully optimised PiColorLock detection reagent and a selection of buffer concentr…

The Thermo Scientific ToxInsight Drug Induced Liver Injury Assay Cartridge for the ToxInsight IVT Platform offers a new multi-parameter cell-based assay to determine the risk of liver injury by chemicals being tested for new drugs or for consumer products safety assessment. The ToxInsight DILI Cartridge is for identifying compound hepatotoxicity by simultaneous detection of multiplexed targets, including cell loss, nuclear DNA…

The Thermo Scientific ToxInsight Endocrine Profiler Panel offers a complete solution for consumer products companies needing to comply with regulatory Reproductive Toxicity testing requirements. Traditional methods of assessing endocrine disruption in vitro measure single targets in homogeneous formats and have a record of low predictive power. The Thermo Scientific ToxInsight Endocrine Profiler Panel leverages our proven tech…

Absolute Automation Is True Walk-Away Freedom for: ■ Sample Preparation ■ Sample Processing ■ Results Analysis Only the TIGRIS® DTS™ System, with Absolute Automation, automates all phases of molecular diagnostics testing from sample preparation, amplification, and detection to reporting results. Integrating the TIGRIS DTS System with APTIMA® assay kits for nucleic acid testing (NAT) offers true freedom from hands-on processing…

The DropArray™ Accelerator HT200 allows higher level of automation for researchers. It provides similar benefits to DropArray™ Accelerator LT100 with additional features required for our high throughput and screening customers. The HT200 is a fully automated washing instrument that can be easily integrated into existing liquid handling systems, and is compatible with traditional plate formats used in imagers and dispensers. It…

The DropArray™ Accelerator LT is the first in a series of products offered by Curiox. The Accelerator LT targets users in research labs performing ELISA and cell adherent assays. The DropArray™ Accelerator is a bench-top liquid handling station that automates the wash step in wash-based bioassays (bioassays that require a wash step in between addition of reagents) by eliminating conventional tedious and long drawn pipetting me…

The IDS-iSYS combines 50 years of instrumentation engineering experience with world-respected assay development skills into a compact, benchtop system that fully automates testing of the most challenging calcium, bone, growth and hypertension markers. Uncompromised Efficiency • Full, walk-away automation • Compact, benchtop design • Continuous loading with Batch, Random, and STAT flexibility • Easy operation with auto start-up…

The VersaMAP Development System offers our widest selection of potential analytes for Luminex-based multiplexing. The diluent supplied is suitable for most cell culture supernate samples. Samples with complex matrices, such as serum and plasma, may need further optimization. For multiplex kits validated by R&D Systems for use in complex matrices, please see our Fluorokine® MAP products. VersaMAP Development System product data…

Fluorokine MAP Kits for the Luminex platform are highly efficient multiplex assays that have been validated for the quantification of factors in complex matrices and require little or no optimization. For a wider selection of analytes, please see our VersaMAP™ line of development kits validated for use with cell culture supernatants. Features Simultaneously detect multiple analytes Requires small sample volume (Undergoes simil…

The VersaMAP™ Magnetic Custom Multiplex Kits are our most efficient Luminex-based multiplex assays. These homogeneous, no wash assays utilize analyte-specific antibodies conjugated to superparamagnetic microparticles to simultaneously detect up to 25 user-defined phosphorylated receptor tyrosine kinases (RTKs) in a single sample. Available Kits VersaMAP Magnetic Human RTK Kit A VersaMAP Magnetic Human RTK Kit B Features • Comp…

Cellstain-Double Staining Kit is utilised for simultaneous fluorescence staining of viable and dead cells.  Flurometric microscope detection, simultaneous determination of viable and dead cells.

An easy way to assess tag accessibilityThe production of fusion proteins often raises the issues not only of their structural integrity after isolation, but also of the accessibility of the associated tag. In the case of GST or 6HIS tagged proteins, this verification can be achieved with HTRF® GST and 6HIS check kits. These two assays are competitive immunoassays in which the anti-GST or anti-6HIS Cryptate conjugates bind dire…

A new secondary messenger for Gq coupled receptor investigation.Cisbio’s IP-One assay, based on its proprietary HTRF® technology, is the first HTS immunoassay that can easily detect inositol(1)phosphate (IP1), a stable second messenger which tightly correlates with Gq-coupled receptor activity. This assay displays all the characteristic advantages of an HTRF® system: totally homogeneous, detection via fluorescence, signal stab…

For general laboratory use. The MagNA Pure LC Total Nucleic Acid Isolation Kit – Lysis/Binding Buffer Refill is designed for lysis of mammalian blood, serum, or plasma samples, and the stabilization of nucleic acids. After the addition of Lysis/Binding Buffer to the sample, the cells are lysed and enzymes (e.g., ribonucleases) are effectively inactivated. The lysed and stabilized samples can be immediately processed (or aft…

For use with:Cat. No. 03 172 627 001 MagNA Pure LC mRNA Isolation Kit II (Tissue) orCat. No. 03 330 591 001 MagNA Pure LC RNA Isolation Kit III (Tissue) For general laboratory use. The MagNA Pure LC RNA Isolation Tissue Lysis Buffer – Refill is designed for lysis and homogenization of fresh frozen tissue samples using a tissue homogenizer (see the MagNA Lyser Instrument) stabilization of total RNA and mRNA within samp…

For general laboratory use. The MagNA Pure LC mRNA Isolation Kit I - Lysis Buffer Refill is designed to lyse mammalian whole blood, blood cells, or cultured cells, and stabilize mRNA.After the addition of Lysis Buffer to the sample, the cells are lysed and enzymes (e.g., ribonucleases) are effectively inactivated. The lysed and stabilized samples can be immediately processed (or after long-term storage) with the MagNA Pure LC…

For use with the MagNA Pure Compact Nucleic Acid Isolation Kit I For general laboratory use. The MagNA Pure Bacteria Lysis Buffer is designed for: lysis of bacteria in many different samples of mammalian origin (e.g., urine, bronchoalveolar lavage [BAL], sputum, cerebrospinal fluid [CSF], swabs) or bacterial cultures stabilization of DNA in sample lysates purification of bacterial DNA with the MagNA Pure Compact Instru…

GFP/RFP-Booster – enhance your fluorescent fusion protein ChromoTek’s Booster are very small, highly specific GFP- or RFP-binding proteins covalently coupled to the superior fluorescent dyes from ATTO-TEC. With our Booster you can: • Reactivate • Boost • Stabilize the signals of your fusion proteinsDirectly stain your protein of interest in fixed cells and benefit from the high specificity an small size that are perfect for su…

Chromobodies® - Your perfect reagents for cellular research including High-Content Analysis. Chromobodies are fluorescent nanoprobes suitable for real time analyses of endogenous cellular structures and processes in live cells. Chromobodies® are a novel species of extremely small intracellular antibodies. They are based on the antigen binding domain (VHH) derived from heavy chain antibodies of camelids genetically fused to a f…

DNA methylation was the first epigenetic modification identified and has been intensively studied for more than half a century. By now it is clear that Dnmt1, the major eukaryotic DNA methyltransferase, faithfully maintains genome-wide methylation patterns and plays an essential role in the epigenetic network controlling gene expression and genome stability during development. However, the molecular mechanisms that ultimately…

Being able to visualize endogenous cellular structures in live cells is key for many high content analyses. The two Chromobodies® of the ChromoTek’s Cell Organelle Toolbox offer a new way to investigate key compartments of the cell non-invasively. Lamin-Chromobody® The new Lamin-Chromobody® is a major breakthrough especially in High-Content Analysis (HCA) as apoptosis assays thus far rely on static endpoint assays. The nucle…