High-Throughput Screening Products & Reviews

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High-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Cell Cycle™ Assay

Merck

For researchers who want to do cell cycle research at their benchtop, Guava Cell Cycle assay can be used for measuring G0/G1, S, and G2/M phase distributions. Based on the established method of whole-cell staining with propidium iodide (PI), Guava's cell cycle assay is easy to learn. Guava Cell Cycle software includes markers that can be set for quick assessment of G0/G1, S, and G2/M phase cell cycle percentages as data is bei…

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Apoptosis Assay Suite

Merck

Apoptosis, or programmed cell death, is a highly regulated pathway that is important in normal developmental processes as well as many diseases. Cells undergoing apoptosis are identifiable by a number of characteristics, including changes in mitochonrial membrane potential, transport of phosphatidylserine (PS) to the membrane surface, activation of caspase proteases, and DNA fragmentation in the nucleus. Guava offers four apop…

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ViaCount™ Assay

Merck

Guava Technologies' ViaCount assay is revolutionizing the way cell counting and viability assessment are done in today's laboratories. Fast, automated, and highly reproducible, the Guava ViaCount assay addresses many of the difficulties of conventional cell counting and viability assessment methods. The Guava ViaCount assay provides: Cell counts up to ten times faster than manual counting, in a convenient turnkey assay.…

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HTRF® KinEASE™ TK

Cisbio Bioassays

Cisbio's HTRF® KinEASE™ platform has expanded to include a universal assay for tyrosine kinases. The HTRF KinEASE TK assay is based on our patented HTRF technology and uses a unique tyrosine peptide substrate in combination with a Europium-labeled monoclonal antibody. The HTRF KinEASE™ TK assay has been validated on 59 tyrosine kinases to-date including both receptor and cytoplasmic TKs. A proprietary substrate stabilizing buf…

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GreenScreen HC

Gentronix Ltd.

Gentronix has launched a new, accurate and fast in vitro mammalian cell genotoxicity assay - GreenScreen HC. The TK6 host cells are p53 competent and familiar to most genetic toxicology laboratories. A patented GFP reporter system exploits the proper regulation of the GADD45a gene. The assay delivers both high specificity and high sensitivity and detects all common mechanistic classes of genotoxin. The 96-well microplate for…

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BioBook (E-WorkBook for biology)

IDBS

BioBook (E-WorkBook for biology) delivers complete late stage discovery and early preclinical research data management. Offering a compliant environment with superior flexibility, BioBook (E-WorkBook for biology) simplifies the capture, analysis and reporting of complex, multi-dimensional experimental data, with interactive complex statistics and graphing. BioBook is a robust and easy to use application that controls every st…

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IP-One ELISA assay kit

Cisbio Bioassays

IP-One ELISA assay kit from Cisbio Bioassays - Simple and highly accurate measurement of IP1 IP1, a downstream metabolite of IP3, accumulates in cells following activation of Phospholipase C (PLC) coupled receptors. Among them, the Gq coupled GPCRs represent the most important family of receptors which can activate the β subtype of the PLC family. Other receptor types, like protein tyrosine kinase receptors, antigen or immuno…

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Nexin Assay Kit

Merck

The new Guava Nexin® reagent monitors induction of apoptosis quickly and easily, with minimal chance for contamination. Annexin V is a calcium-dependent phospholipid binding protein with high affinity for phosphatidylserine (PS), a membrane component normally localized to the internal face of the cell membrane. Early in the apoptotic pathway, molecules of PS are translocated to the outer surface of the cell membrane where Ann…

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mTOR Kinase - a part of the KinaseProfiler™ Service

Merck

Millipore's full-length mTOR kinase is now available as part of the KinaseProfiler™ Service. This kinase is the first biologically relevant mTOR to be commercially available. The KinaseProfiler Service offers 264 kinases for selectivity profiling, using a catalytic radiometric assay format. The addition of the full-length mTOR to the KinaseProfiler panel provides high-quality, confidential screening of compounds against this c…

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A-S 21 CFR Part 11 Toolkit

Aitken Scientific Ltd Software Integration

Aitken Scientific have created a software product called A-S Login (fully validated to GAMP standards) which will enable the pharmaceutical industry and its suppliers to minimise cost and time when implementing the requirements of 21 CFR Part 11.     • Maintains permitted applications, allowing versions and access rights to be controlled.     • Maintains the list of authorised users             o Password administration…

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Caspase 3 Activity Assay

ApplicationSamples suitable for the Caspase 3 Activity Assay are: Lysates of apoptosis-induced cells Recombinant caspase 3 (CPP32) The Caspase 3 Activity Assay can be used to: Detect and quantify in vitro caspase 3 activity in cell lysates Analyze caspase 1, 2, 3, or 7 activity by simply omitting the capture-antibody step Perform inhibitor studies for Caspase 3 This kit is intended as a tool for life science…

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cAMP-Screen® and cAMP-Screen Direct® Chemiluminescent Immunoassay System for Determination of cAMP Concentration

Thermo Fisher Scientific

This family of kits provides ultra-sensitive, non-radioactive quantitation of cyclic adenosine monophosphate (cAMP) in cell lysates. - Accuratelly detect less than 60 femtomoles of cyclic adenosine monophosphate (cAMP) in cell lysates. - Grow cells and run the assay in the same plate, eliminating loss of cell lysates from transferring (cAMP-Screen Direct™ System only). - Reduce interference from test compounds and improve CVs…

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Dual-Light® Combined Reporter Gene Assay System for Detection of Luciferase and beta-Galactosidase

Thermo Fisher Scientific

Dual-Light® luminescent reporter gene assay is designed for the rapid and sensitive detection of firefly luciferase and b-galactosidase in a single extract aliquot for gene expression assays. Detection of firefly luciferase and b-galactosidase in the same sample simplifies normalization of transfection efficiency Wide dynamic range of b-galactosidase and luciferase assays enables accurate measurement of both enzymes from…

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Human IFN Alpha Sampler (12 individual subtypes 20,000 units each)

PBL InterferonSource

Recombinant Human IFN Alpha Sampler, 12 individual subtypes including: Human IFN-alpha A, B2, C, D, F, G, H2, I, J1, K, 4b, WA Catalog Number: 11001-1 Activity: Request Info Source: E. Coli  Accession Number: Request info Size: 1 kit Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon, Sampler, SubtypeShipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Pre…

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Human IFN Alpha A (Alpha 2a)

PBL InterferonSource

Recombinant Human IFN Alpha A (Alpha 2a), Gene IFNA2 Catalog Number: 11100-1 Activity: 8.7 x 108 u/mgSource: E. Coli Accession Number: V00549Size: 5 x 106 unitsPurity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon, Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effectiv…

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Human IFN Alpha A, (Alpha 2a) carrier-free

PBL InterferonSource

Recombinant Human IFN Alpha A (Alpha 2a), Gene IFNA2 Catalog Number: 11101-2 Activity: 8.7 x 108 u/mg Source: E. Coli Accession Number: V00549 Size: 20 µg Purity: ≥ 95% Formulation: Frozen without a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon,Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°CPreservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 10/1/2007):…

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Human IFN Alpha 2 (Alpha 2b)

PBL InterferonSource

Recombinant Human IFN Alpha 2 (Alpha 2b), Gene IFNA2 Catalog Number: 11105-1 Activity: 1.7 x 108 u/mg Source: E. Coli Accession Number: V00548 Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon, Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 10/1…

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Human IFN Alpha B2 (Alpha 8)

PBL InterferonSource

Recombinant Human IFN Alpha B2 (Alpha 8), Gene IFNA8 Catalog Number: 11115-1 Activity: 4.6 x 108 u/mg Source: E. Coli Accession Number: X03125  Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon, Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 1…

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Human IFN Alpha C (Alpha 10)

PBL InterferonSource

Recombinant Human IFN Alpha C (Alpha 10), Gene IFNA10 Catalog Number: 11120-1 Activity: 2.3 x 108 u/mg Source: E. Coli Accession Number: X02961 Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon, Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 10/…

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Human IFN Alpha D (Alpha 1 [Val 114])

PBL InterferonSource

Recombinant Human IFN Alpha D (Alpha 1 [Val 114]), Gene IFNA1 Catalog Number: 11125-1 Activity: 7.5 x 107 u/mg Source: E. Coli Accession Number: V00538 Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier proteinProtein Synonyms: IFN, Interferon, Type I Interferon, Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effect…

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Human IFN Alpha F (Alpha 21)

PBL InterferonSource

Recombinant Human IFN Alpha F (Alpha 21), Gene IFNA21 Catalog Number: 11130-1 Activity: 6.4 x 108 u/mg Source: E. Coli Accession Number: V00540  Size: 1 x 105 units Purity: ≥ 95% Formulation: Frozen with a carrier protein Protein Synonyms: IFN, Interferon, Type I Interferon, Subtype Shipping Conditions: Dry ice Storage Temp.: -20˚C/-70°C Preservative: N/A Shelf Life: 2 years from date of receipt 2007 Retail price (Effective 10…

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