UHPLC and HPLC Products & Reviews

The 1260 Infinity III Multi-Method System offers maximum system utilization with minimum manual interaction. Give multiple users HPLC access to their personalized methods - all on one system. This HPLC multi-method system hosts the different everyday HPLC methods of multiple scientists and provides automated switching to run the personalized methods without the need of manually changing column or solvent.

The 1290 Infinity III Multi-Method System offers highest system utilization and automation with multiple method UHPLC capabilities for different users at the same system. This UHPLC Multi Method system hosts different methods on one system, backed by highest chromatographic performance, to give multiple scientists access to their personalized UHPLC methods.

The 1260 Infinity III Amino Acid Analysis System provides a complete solution for the automated HPLC amino acid analysis. It combines the latest developments in HPLC instrumentation and column technology with proven precolumn derivatization chemistry for fast and sensitive amino acid analysis.

The 1260 Infinity III SFC Control Module is a carbon dioxide conditioning unit for supercritical fluid chromatography. This module pre- and postconditions CO2 for InfinityLab SFC solutions. CO2 preconditioning provides for unmatched stability and precision of retention times, and postconditioning enables trouble-free connection to mass spectrometers. 

The 1260 Infinity III Prime Bio LC System is a versatile HPLC instrument for bioseparations and offers outstanding functionality and operational convenience for biochromatography, and entry-level quaternary bio UHPLC at pressures up to 800 bar and flow rates up to 5 mL/min.

The 1260 Infinity III Prime Analytical-Scale LC Purification System is a versatile preparative high-performance liquid chromatography (HPLC) instrument. This system offers the highest functionality and operational convenience for analytical-scale HPLC purification and entry-level quaternary UHPLC at pressures up to 800 bar and for flow rates up to 5 mL/min.

The 1260 Infinity III Prime Bio Analytical-Scale LC Purification System is a versatile preparative high-/ultrahigh-perfomance liquid chromatography (HPLC/UHPLC) system for bioseparations. The system offers outstanding functionality and operational convenience for bioanalytical HPLC and entry-level quaternary bio UHPLC at pressures up to 800 bar and flow rates up to 5 mL/min.

The 1260 Infinity III Bio-Inert Analytical-Scale LC Purification System is a dedicated solution for purifying large biomolecules in biological samples, including monoclonal antibodies and proteins.

The 1290 Infinity III Bio Analytical-Scale LC Purification System is an ultrahigh-performance liquid chromatography (UHPLC) system, configurable with a binary or quaternary pump and consisting of biocompatible material for use in biopharma (such as for critical quality attributes).

ExionLC AE system provide full integration, control and compatibility with SCIEX mass spectrometers bringing together the speed and precision you expect for a complete solution that meets every challenge your lab faces.

The M5 MicroLC system is a feature rich microflow LC-MS solution meant to simplify both small and large molecule quantitation and characterization. In addition to using a small sample size, this extremely sensitive, versatile instrument will help you save on costs and space, and fully integrates with your SCIEX mass spectrometer of choice.

Bioinert coated YMC Accura BioPro IEX columns provide excellent peak shapes for sensitive compounds, ensuring high recovery from the very first injection.

RP and HILIC bioinert YMC Accura Triart columns are available for the analysis of critical substances including selected proteins, (oligo)nucleotides and metal-coordinating compounds such as organophosphates.

This new strong anion exchange resin offers an optimised macro-porous structure that ensures an efficient purification of large biomolecules, such as adeno-associated viruses (AAVs) and plasmid DNA (pDNA). With its high binding capacity for such molecules and high separation efficiency even at elevated flow rates, MacroSep IEX Q is a perfect addition to DSP platforms.

Specialized Columns for Mixed Polar and Nonpolar Compounds.

Acclaim™ Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. his new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily opti…

The Thermo Scientific Acclaim™ Explosives E1 (5 µm) and E2 (5, 3 and 2.2 μm) silica-based reversed-phase columns are designed to resolve all 14 explosives listed in EPA SW-846 Method 8330: Nitroaromatics and Nitramines by HPLC. Their unique chemistries deliver superior resolution with complementary selectivities. The E1 is recommended for use as a direct replacement for ODS columns for the primary analysis.The E2 may be used a…

High-Resolution Separation of Proteins and Peptides The Acclaim® 300 features 3 µm silica particles for rapid analysis of complex protein digests. The Acclaim 300’s stable bonding make these columns compatible with a wide variety of applications, including LC/MS methods.Manufacture of these columns starts with ultrapure silica that contains minimal concentrations of metal contaminants, minimizing the tailing effects of residua…

The DNASwift™ SAX-1S is a strong anion-exchange column that provides exceptionally high resolution for the purification of oligonucleotides.The exceptionally high resolution provides superior purity and yields compared to other ion-exchange or reversed-phase columns available. The DNASwift column is ideal for therapeutic and diagnostic research, which have very high purity and yield oligonucleotides purification requirements.T…

The Thermo Scientific Acclaim™ PepMap™ 100 C18 column sets the benchmark in peptide separation.The PepMap100 C18 column is available in 3 or 5 µm particle sizes, with 100 Å pore sizes, and in nano, capillary, and micro formats. nanoViper fingertight fittings allow for easy column installation.Column Details: Chemistry: C18 Particle Size: 3, 5 μm Pore Size: 100 Å Length: 5, 15, 25, 50 mm ID: 75, 300 μm, 1.0 mm

Acclaim™ PepMap300 C18 is used for the separation of larger peptides and proteins.It is available in 5 µm particle sizes, with 300 Å pore sizes, and in nano, capillary, and micro formats.Column Details: Chemistry: C18 Particle Size: 3, 5 μm Pore Size: 100, 300 Å Length: 5, 15 mm ID: 75, 300 μm, 1 mm

MAbPac™ SCX-10 Columns for the High-Resolution Separation and Analysis of Monoclonal Antibody VariantsThe Thermo Scientific™ MAbPac™ SCX-10 column line has been expanded to include 3 and 5 μm particle sizes for fast, high-resolution analysis as well as rapid separation (RS) columns for bio-UHPLC separations. These smaller-particle-size columns provide the same high resolution as the 10 μm columns, but with…

High-Resolution, Strong and Weak Anion-Exchange Columns for the Separation of ProteinsThe ProPac® SAX-10 is a nonporous, strong anion-exchange column (quaternary amine functional group). The ProPac WAX-10 column is a weak anion exchanger (tertiary amine functional group). Both are based on a nonporous core particle that provides pressure stability. A hydrophilic layer prevents unwanted secondary interactions and a grafted anio…

Strong and Weak Cation-Exchange Columns for High-Resolution Separation of Proteins and MAbsThe Thermo Scientific ProPac™ SCX column line has expanded to include the next generation ProPac SCX-20 column. This column provides unequalled high resolution of protein variants.ProPac SCX-10 and WCX-10 strong and weak cation-exchange columns are based on a nonporous core particle that results in high-efficiency peaks and high-resoluti…

For Hydrophilic Anionic Protein SeparationsThe ProPac® PA1 column supports the analysis and purification of hydrophilic anionic proteins and peptides. Proteins and peptides that are highly cationic (e.g., those with very high isoelectric points) may be resolved on this column, but some may exhibit substantial binding to the column.ProPac® PA1 Protein and Peptide Column Features: Good for hydrophilic anionic proteins and pepti…