SPR Based Biosensor Systems Products & Reviews

Binds human IgGs and human Fc-fusion proteins. Recommended for rapid screening for quantitation, off-rate ranking for antibodies, kinetic screening, and epitope binning.

Binds IgGs of various species, including human and mouse. Dynamic range of 0.02 – 2000 µg/mL. Can be robustly regenerated.

Binds IgGs of various species, including human and rat. Dynamic range of 0.02 – 2000 µg/mL. Can be robustly regenerated.

Binds IgGs of various species through the kappa light chain. Dynamic range of 0.02 – 2000 µg/mL.

Binds His-tagged proteins. Can be used for rapid quantitation, kinetic measurements and epitope binning. Can be regenerated.

Used to bind hydrophobic proteins or to create custom-made biosensors.

The Gator ® Ni-NTA probes enabler rapid and continuous quantification of His-tagged proteins without the need for Ni2+ recharging. The stable immobilization of His-tagged proteins allows for facile kinetics analysis with binding partners, off-rate screening, and epitope binning of antibodies experiments.

Gator Bio offers many on-demand probes such as  Anti-RBD  SARS-COV-2; Anti-Rabbit; Anti-Rat; Anti-Flag 

Multichannel Cartridge-Based Benchtop SPR platform for seamless handling of biological or clinical samples.  

Custom SPR sensor chips tailored for Affinité Instruments’ P4SPR and qSPR. Range of surface chemistries to choose from (e.g. amine coupling, Ni-NTA).    

The Gator ® AAV9 Probes are high specificity nanobody-based biosensors that enable direct capture and quantitation of AAV9 in crude lysates, column eluates, cell lysates and cell culture supernatants. The Gator ® AAV9 probe uses proven CaptureSelect™ (Thermo Fisher Scientific) high affinity and high specificity anti-AAV9 nanobody.

HFCII probes are high-performance nanobody-based biosensors that can detect and quantitate human IgG and its isotypes in different buffers (Q, K), cell culture supernatant, cell media, and other crude samples. Dynamic range: 0.3-6000 µg/mL in Q buffer; 1-2000 µg/mL (in diluted cell culture media).

BLI 96-Flat Plate, Polypropylene (10 plates/pack, 10 packs/case)

The Gator ® High Sensitivity (HS) AAV9 Kit enable high sensitivity quantification of AAV9 in crude and purified samples. The HS AAV9 Kit includes: HS AAV9 probes (96 probes/tray) HS AAV9 Detection Solution AAV Amplification Solution AAV Substrate Solution AAV Substrate Diluent Q Buffer ** Contains temperature sensitive components. Must be shipped overnight. ** *Not compatible with Gator ® AAV9 probe (Part No. 160021)

Streptavidin probes for kinetic analysis of a wide range of biomolecules such as peptides, proteins, and large lipid nanoparticles.

Extending walk-away time while delivering fast, reproducible and high-quality data The Gator ®  Pro instrument is designed for fast, automated, high-throughput analysis. 32 spectrometers enable high frequency parallel measurement of up to 32 samples. 3 sample plates enable automated data acquisition of 1152 samples per batch.   

Binds biotinylated proteins with near covalent linkage. Sensor can be fully reactivated over 20+ times. Kit includes: 24 Flex SA probes 3 bottles of priming reagent (50mL/bottle) 1 bottle of Capture reagent (20mL/bottle) 1 bottle of reactivation reagent (20mL/bottle) 1 bottle of K buffer (30mL/bottle) Plate foil

High-capacity streptavidin biosensors to be used for measuring small molecules and peptides binding to protein targets. Intended for affinity measurements of small molecule or peptide binding to a biotinylated (or AviTag containing) biomolecule.  

Containing agents to decrease nonspecific binding and background signal of crude samples, this buffer was specially formulated for quantitation measurements using the Gator system and comes ready to use with any of our biosensors.

Containing agents to decrease nonspecific binding and stabilize the baseline, this buffer was specially formulated for kinetics analysis using the Gator system and comes ready to use with any of our biosensors.

Ni-NTA Regen and Ni-NTA Neutral Buffers allow for continuous regeneration of the Ni-NTA (i.e., Tris-NTA and charged with Ni2+ ions binding to His-tagged proteins) probes, without the need for an additional Ni2+ recharging step. Is used for regeneration up to 20 times, with no loss in biding rate.

High-purity buffer for kinetics applications. Proprietary ingredients allow for analysis of pM affinity interactions. Perfect for your most difficult-to-work-with biomolecules. Compatible with SA and amine-reactive biosensors.

96-well plates designed for Gator ® probes holder. 250 µL solution amount but goes up to 280 µL. For probes, reagents. Pack of 10 per quantity.

96-well plates designed for Gator ® probes holder. 250 µL solution amount but goes up to 280 µL. For probes, reagents. The lids offer storage of/a cover for probes. Pack of 10 per quantity.

Includes reagent set for reactivating the Flex SA probe. Kit includes: 3 bottles of priming reagent (50mL/bottle) 1 bottle of Capture reagent (20mL/bottle) 1 bottle of reactivation reagent (20mL/bottle) 1 bottle of K buffer (30mL/bottle) Reactivate probes over 20+ times