Preparative Chromatography Products & Reviews

Highly flexible chromatography system for process scale-up and large-scale manufacturing

This new strong anion exchange resin offers an optimised macro-porous structure that ensures an efficient purification of large biomolecules, such as adeno-associated viruses (AAVs) and plasmid DNA (pDNA). With its high binding capacity for such molecules and high separation efficiency even at elevated flow rates, MacroSep IEX Q is a perfect addition to DSP platforms.

YMC HT Glass Columns are specially designed to accommodate the stringent requirements of high-temperature liquid chromatography applications. Capable of performing efficiently at temperatures up to 70 °C, these columns are perfectly suited for a broad spectrum of purification tasks, particularly in biochemical liquid chromatography (BioLC), where high temperatures are pivotal.

BioPro IEX, YMC's strong ion exchange material are based on a hydrophilic polymer which provides low non-specific adsorption and high recoveries. Porous and non-porous polymer beads are available for high loadability and throughput.  

Rugged, Reliable SFC Purification of Compounds

With YMC-Triart Prep, pH stable preparative HPLC stationary phases are available for industrial-scale applications. This hybrid silica-based material can be used in a pH range of 2.0 - 10.0 and allows more efficient cleaning procedures. The innovative YMC-Triart Prep combines mechanical strength and pH stability.

From laboratory to pilot scale, YMC offers reliable, high quality glass columns for all kind of application areas.

YMC PilotPLUS columns are completely biocompatible and characterised by safe and easy handling.

Does your application require customised pilot columns? With YMC Pilot columns, customised versions can be constructed to address your needs. Of course standard dimensions are available, too!

BioPro IEX and BioPro IEX SmartSep resins are specifically designed for biochromatography. They are available as a strong anion exchanger (BioPro IEX Q) and a strong cation exchanger (BioPro IEX S). The resins are based on a hydrophilic polymer matrix, with a particle size of 10 µm, 20 µm, 30 µm and 75 µm.

Highly robust hybrid silica material for the purification of proteins, peptides and oligonucleotides, which combines mechanical strength and pH stability. The larger pore size makes YMC Triart-Prep Bio200 C8 the ideal choice for the purification of mid-size to large biomolecules.

The Prep 150 LC System is a fit for purpose solution designed for scientists requiring robust system performance with intuitive software for dedicated personal purification or quick adoption in centralized labs. Systems are designed to satisfy your application requirements, whether you are processing a few samples a day, or your workload demands greater through-put with unattended automation. The Prep 150 LC System allows you…

Waters offers PoraPak™ Rxn, a family of polymer-based chromatography products for superior cleanup of synthetic reactions. PoraPak Rxn products are available in two chemistries: PoraPak Rxn CX, a strong cation-exchange sorbent and PoraPak Rxn RP, a reversed-phase sorbent.PoraPak Rxn sorbents are based on copolymers that exhibit the following properties:Hard material that does not develop increasing back pressure with flowLitt…

The VERITY Compact CPC System combines a PLC Purification System with a centrifugal partition chromatography (CPC) system for high-level target compound purification.

Validated high performance prepacked columns for scale-up and GMP biomanufacturing

TSKgel Phenyl-3PW (20) process resin provides a novel solution for the purification of oligonucleotides. This resin is capable of cleaving DMT protective groups on-column in order to streamline downstream bioprocessing of complex oligo species.

TOYOPEARL Super A is a novel, robust protein A resin designed to efficiently purify mAbs and other antibody species like ADCs and bispecifics. This resin offers high alkaline stability, exceptional dynamic binding capacity, and a polymer base bead able to withstand high linear velocities.

TOYOPEARL MX-Trp-650M is a high capacity mixed-mode resin used for the purification of monoclonal antibodies and other proteins.

MAGic™ Beads Ultra-Speed Streptavidin are super-paramagnetic porous beads optimized for streamlined extraction of biotinylated proteins for your customs laboratory needs in an automated robotic set up, eliminating the need for extensive processing time and low-quality results. The exceptional magnetization, low magnetic reminiscence and high binding capacity enables fast capture in a magnetic field and rapid resuspension with…

MAGic™ Beads Protein G offer one-step clarification and capture of monoclonal antibodies, which do not have an affinity towards Protein A. It eliminates the need for centrifugation, depth filtration and Protein G affinity column-chromatography. Super-paramagnetic porous beads coupled with a Protein G ligand.

MAGic™ Beads Protein A offer one-step clarification and capture of monoclonal antibodies, eliminating the need for centrifugation, depth filtration and Protein A affinity column-chromatography. Super-paramagnetic porous beads coupled with an alkali resistant Protein A ligand.

The MAGic™ Beads Ultra-Speed Oligo(dT) are super-paramagnetic porous beads optimized for streamlined extraction of mRNAs in an automated robotic set up, eliminating the need for extensive processing time and low-quality results. The exceptional magnetization, low magnetic reminiscence and high binding capacity enables fast capture in a magnetic field and rapid resuspension with minimized power input. The magnetic beads are com…

Our pre manufactured custom ACT beads for your in-house coupling of ligands. Any ligand containing amino groups or thiols, e.g. proteins and peptides can be covalently bound to the beads using a simple process. All steps are performed at physiological conditions and room temperature, without using any hazardous reagents or organic solvents. After coupling of the ligand, the magnetic beads can be used for affinity purification…

Custom-design for your application. MAGic Bioprocessing are specialized in the development and production of tailor-made magnetic bead products for a variety of different applications.

MAGic™Accio PILOT perfectly supports the development phase, medium-scale processing of nucleic acids, peptides, proteins, such as antibodies and viruses from clarified- or unclarified cell-culture mixtures. The separation is performed in sample volumes from 5 ml up to a couple of liters. The use of the MAGic™Accio PILOT 50, MAGic™Accio PILOT 500 and MAGic™Accio PILOT 2000 together with 20µl – 250ml of settled MAGic™Beads offer…