Oligonucleotides Products & Reviews

Licence-free MGB probes for any application

Our engineers designed the rCPC platform for pilot-scale purification tasks within a laboratory environment. It is ideal for all batch sizes, smaller or larger, or campaign type of research work, and continuous-batch production. To accommodate a user-friendly operation, RotaChrom offers a turn-key solution package for semi-automated solvent handling (preparation and recovery) upon request. rCPC can be utilized as an at-line p…

Glen Research CE (β-cyanoethyl) Phosphoramidites are produced and packaged to ensure the highest performance on DNA synthesizers. Every Glen Research product is accompanied by a Certificate of Analysis and HPLC trace, showing the results of our QC testing. Glen Research monomer vials are specially cleaned to eliminate particulate contamination, and each vial type is tested or inspected to ensure a tight fit on synthesizers.

All Glen Research CPG supports use the standard long chain alkylamino (lcaa) linker but differ in the glass pore size, 500Å, 1000Å or 2000Å.

From deblocking to oxidation, unlock the highest levels of performance at each step of the oligo synthesis cycle with ancillary reagents from Glen Research.

Glen-Pak™ cartridges utilize the 5’ DMT retained on an oligonucleotide to specifically bind full-length sequences to the support. During the purification process, the failure sequences are eliminated and the DMT is subsequently removed, allowing for elution of purified product.

Effective, stable, non-aqueous oxidizer for DNA synthesis

A Potent Modification with Many Applications

MGB Eclipse ® pairs a minor groove binding (MGB) tripeptide with a dark quencher. The MGB significantly enhances hybridization, while the Eclipse ® has a broad absorption range that quenches many of the most common fluorophores, including FAM, HEX, TET and Yakima Yellow ® .

Copper-free click chemistry phosphoramidites

Tools for fine-tuning protein function

Universal CPG solid support for oligonucleotide synthesis

Phosphoramidite for the incorporation of an abasic spacer internally or at the 5' end of an oligonucleotide.

Phosphoramidite used to incorporate a 5' biotin functionality, separated from the oligonucleotide by a photo-cleavable linker.

Phosphoramidite used to incorporate the cyanine-3 dye moiety into an oligonucleotide.

CPG for incorporation of an (otherwise unmodified) reverse (5' to 3') dT nucleobase at the 3' end of an oligonucleotide.  

CPG used to add the non-fluorescent quencher BHQ-1 dye to the 3' end of an oligonucleotide.

CPG for incorporation of unmodified DNA base at 3' end of an oligonucleotide.

CPG for incorporation of unmodified DNA base at 3' end of an oligonucleotide.

CPG for incorporation of unmodified RNA base at 3' end of an oligonucleotide.

CPG for incorporation of unmodified RNA base at 3' end of an oligonucleotide.

CPG for incorporation of unmodified DNA base at 3' end of an oligonucleotide.

CPG for incorporation of unmodified RNA base at 3' end of an oligonucleotide.

CPG for incorporation of unmodified RNA base at 3' end of an oligonucleotide.

CPG for the incorporation of a 2'-fluoro modified nucleobase at the 3' end of an oligonucleotide