Cell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.
BlueScreen HC uses a single cell strain, which permits 8 compounds to be tested across 8 dilutions (2-fold serial), together with untreated and positive controls, in one 96-well microplate. After arraying test compounds and dilutions, growing cells are added to each well. For studies without S9 metabolic activation data are collected after incubation (48h) using a multimode microplate reader. For studies incorporating S9 metab…
Sensitive DNA damage assessment Very low compound requirement Rapid turnaround, ideal for screening Reliable testing by genetic toxicology experts Assay Principles The Comet assay, also called single cell gel electrophoresis, is a technique used for the sensitive detection of DNA damage in individual cells following exposure to a test compound. Electrophoresis is performed on exposed cells that have been embedded i…
Nano BioDiscovery provides a comprehensive line of services for a wide range of proteins, including: • Custom protein array printing • Complete assay development and analysis • Protein profiling services • Technology transfer Each contract service project begins with the client specifying their proteins of interest. NanoInk’s dedicated Contract Research Organization then works in close consultation with the customer to design…
Blue Sky Biotech's TDA 2.0™ is a stable lipid-based nanoparticle with nickel-chelating moieties for use in assembling purified histidine-tagged proteins which are normally membrane associated. TDA 2.0™ allows scientists to study membrane-associated proteins in a way that restores the essential biological environment created by the cell membrane. This synthetic template restores the organizing features of the membrane without t…
Components of the Upstate (Millipore) Casein Kinase 2 Assay Kit:• Casein Kinase 2 Substrate Peptide (Cat.# 12-330) • Assay Dilution Buffer I (ADBI) (Cat.# 20-108) • PKA Inhibitor Cocktail (Cat.# 20-114) • Magnesium/ATP Cocktail (Cat.# 20-113) • P81 Phosphocellulose Squares (Cat.# 20-134) For use to measure the phosphotransferase activity of Casein Kinase 2 (CK-2) in immunoprecipitates and column fractions based on phosphorylat…
R & D Systems Active STAT3 DuoSet IC® Kit - For the development of transcription factor assays to measure human and mouse active STAT1 p91. The R & D DuoSet IC Phospho-specific ELISA format is a sensitive and convenient phosphorylation assay for use with cell lysates. The DuoSet IC signal transduction assays are an excellent alternative to Western blot, especially when used in combination with DuoSet IC ELISAs designed to mea…
Assays for methylases, acetylases, phosphorylases and other modifying enzymes involved in histone and chromatin modulation are developed and optimized by RapidFire scientists for primary and secondary screens. Although histone modifying enzymes can be difficult to analyze by traditional methods, label-free RapidFire technology is well suited to this novel and emerging class of targets.
