Sigma-Aldrich® Cas9 proteins
MerckWith the largest portfolio of Cas9 proteins available, Merck make it easy to find the perfect nuclease for your gene editing experiment.
Gene Expression and Molecular Cloning Products & Reviews
Molecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
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Synthetic guide RNA for CRISPRi applications
For transient gene repression with CRISPR-level specificity
Lentiviral guide RNA for CRISPRi applications
Horizon's CRISPRi guide RNA in an easy to deliver lentiviral format
CRISPRi dCas9 lentiviral particles
Horizon's proprietary dCas9-SALL1-SDS3 CRISPRi repressor in lentiviral particle format
CRISPRi for Transcriptional Interference
A direct and efficient set of tools to study a gene’s function by transcriptional interference in its native context
Single Cellome™ Unit SU10
Yokogawa Electric CorporationSU10 is a nanopipette-based tool for efficient and controlled delivery of material (such as CRISPR Cas9 complex, RNA, proteins) into the nucleus or cytoplasm of single cells in a highly automated manner. The CRISPR Cas9 complex can be delivered directly into the nucleus of a specific target cell in a minimally invasive manner through the utilized glass pipette in nanometer range (approx.100 nm).
CRISPRi Libraries, Pools, and gRNAs
MerckNuclease-independent applications of CRISPR provide equal targeting specificity but instead of cutting, CRISPRi allows for targeted interference of gene function by delivering transcriptional repressor domains to a specific target sequence using modified dCas9 + gRNA complexes. Gene knockdown is complementary to CRISPR-KO and CRISPRa (activation) and has distinct advantages over existing loss-of-function strategies like RNAi.…
Gibco™ CTS™ TrueCut™ Cas9 Protein
Thermo Fisher ScientificGMP-manufactured Cas9 protein for clinical research