LC-MS Products & Reviews

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LC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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EXP® Ti-lok™ Fitting

Optimize Technologies, Inc.

The EXP Ti-lok Fitting features a two-stage locking mechanism ideal for PEEK-clad or sleeved fused silica, such as PEEKsil™ tubing. The two-stage fitting features a patented auto-adjusting titanium hybrid ferrule that seats in any port. The titanium collet locking mechanism provides a second grip point to even the pressure load over the tubing and not crush the silica. The incorporated rear collet locking mechanism is not remo…

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Metabolite Identification (Met ID) for Oligonucleotides

ChemPartner

Our Metabolite Identification service employs HRMS /LC-MS/MS to decode degradation pathways of antisense oligonucleotides (ASOs), siRNAs, and modified variants, identifying chain-shortened metabolites (5’/3’ cleavage), phosphorothioate changes (desulfurization, inversion) and base/nucleotide alterations (deamination/depurination). Through plasma/tissue/cell analysis, we reveal metabolic stability, biodistribution, and exonucle…

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timsMetabo™

Bruker Applied Mass Spectrometry

The timsMetabo™ is uniquely designed to deliver unprecedented sensitivity, separation power and annotation confidence for small molecules. Bruker’s technology and workflow innovations combine depth and selectivity for the ultimate in profiling and targeted applications.

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AccuTOF™ LC-Express Time-of-Flight Mass Spectrometer

JEOL USA

The JMS-T100LP AccuTOF™ LC-Express 4G Time-of-Flight Mass Spectrometer is based on our award-winning AccuTOF time-of-flight analyzer platform. The AccuTOF analyzer design employs elegant ion optics and an ADC-based digitizer to deliver a dynamic range exceeding 4 orders of magnitude, without compromising sensitivity, resolution or mass accuracy.

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SEQUEST® Cluster

Thermo Fisher Scientific

SEQUEST Cluster is a complete, preconfigured proteomics solution that enables accelerated throughput of increasingly complex, multidimensional informatics.Product detail:The SEQUEST Cluster offers a scalable solution for computing the large volumes of data typical in most proteomics analyses using LC/MS. Protein database search times are dramatically reduced by harnessing the power of several processing units in one, increasin…

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DigestPro MSi

Intavis Inc.

Enzymatic digestion of proteins in polyacrylamide gel slices and subsequent analysis of the peptides by mass spectrometry has become a routine procedure in protein analysis. In solution digestion protocols for bottom-up proteomics complement it. The DigestPro MSi automates all those procedures to achieve high throughput under controlled and reproducible conditions.

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Channeltron® Electron Multipliers

Photonis

PHOTONIS Channeltron detectors provide the highest sensitivity due to superior signal collection and noise reduction, effectively improving the efficiency of your mass spectrometer. With over 150 replacement detectors to choose from, we can supply the replacement detector in a wide range of mass spectrometers, even if the instrument is no longer manufactured. Additionally, many of our detectors can be bought as complete repl…

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Advanced Performance Detectors

Photonis

PHOTONIS’ Advanced Performance Detectors (APDs) are plug-and-play electo-optic assemblies which provide a complete housing, facilitating manufacturing assembly, repair or replacement to mass spectrometers and other machines. Available for new machines or as replacement cartridges for existing models, over 200 types, with cartridge-mounted MCP, further simplifying additional repairs. ¶PHOTONIS Advanced Performance Detectors (AP…

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Gen2 UltraFast™ TOF Detectors

Photonis

PHOTONIS offers the widest and most technologically advanced variety of Time-of-Flight Detectors available. These patented detectors offer previously unobtainable levels of temporal resolution, dynamic range, and high mass detection sensitivity for TOF Mass Spectrometry. PHOTONIS' unique 2-Micron pore MCP provide the highest channel density of any MCP providing gains in excess of 5x106. PHOTONIS manufactures Time-of-Flight Det…

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Microchannel Plates

Photonis

PHOTONIS is the industry leader in technology advancements for Microchannel Plates (MCPs). We offer a broad range of sizes, shapes and options to support a number of imaging applications. Our expertise across two production locations ensures continual research and development while ensuring our customers receive the customization and service for which we are known. For over thirty years, PHOTONIS has consistently set the stand…

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Finnigan™ vMALDI™

Thermo Fisher Scientific

The Finnigan vMALDI Ion Source system provides fast, automated MS and Data Dependent MS/MS analysis of digested protein mixtures in a single, rapid experiment. While LC/MS analysis times are typically 30 to 60 minutes, using the Finnigan LTQ with the vMALDI ion source generally requires less than a minute per sample enabling high throughput protein identification. Production: The Finnigan vMALDI Ion Source Thermo's new F…

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LC/MS LaChrom Elite HPLC with 3100 Mass Detector

Hitachi High Technologies America, Inc.

With the addition of the highly flexible and versatile 3100 Mass Detector, Hitachi’s LaChrom Elite ® HPLC System further solidifies its position as the leader in chromatographic analysis for a wide range of applications. The LaChrom Elite® HPLC system, in combination with the Waters® 3100 Mass Detector, provides unmatched selectivity, sensitivity and throughput for improved laboratory productivity. Features Seamless inte…

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compact - Instant Expertise™ in Accurate Mass LC-MS/MS

You expect the fullest possible insight into your sample. compact delivers the highest quality of results without compromise. All specified performance parameters simultaneously delivered in a single run with no need for tuning or optimization is what makes compact unique. Full Sensitivity Resolution Having to choose between resolution and sensitivity on other instruments restricts depth to which you can understand your sample…

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