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PhenoCode Signature Immune Profile Human Protein Panel

Akoya Biosciences

The composition of immune cells within the tumor microenvironment, such as T cells, B cells, and macrophages, varies between tumors and is strongly associated with outcomes to combination therapies. PhenoCode Signature Immune Profile panel enables profiling of the tumor microenvironment using 4 key immune cell markers (CD8, CD68, CD3e, CD20) and a tumor marker (PanCK). Map additional phenotypes by adding a 6th marker to the pa…

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PhenoCode Signature Activated TIL Status Human Protein Panel

Akoya Biosciences

The ability to determine whether tumor cells are proliferating and T cells are activated could provide important information about the anti-tumor response and be an indicator of prognosis. PhenoCode Signature Activated TIL Status panel (CD8, CD3e, Ki67, Granzyme B, PanCK) enables determination of Ki67 positivity in addition to profiling of the tumor microenvironment for CD8+ T lymphocytes that are activated. Map additional phe…

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PhenoCode Signature M1/M2 Polarization Human Protein Panel

Akoya Biosciences

Tumor associated macrophages (TAMs) play a key role in regulating the inflammatory or immunosuppressive state of the tumor microenvironemnt (TME). Distinguish between M1 (pro-inflammatory) and M2 (anti-inflammatory) TAMs using the PhenoCode™ Signature M1/M2 Polarization panel (CD8, CD68, CD163, PD-1, PD-L1) to evaluate polarization profiles in the TME. Map additional phenotypes by adding a 6th marker to the panel from the anti…

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PhenoCode Signature T Cell Status Human Protein Panel

Akoya Biosciences

As the major population of immune cells within the tumor microenvironment (TME), T cells are a driver of anti-tumor immunity. T cell exhaustion and the presence of immunosuppressive cells can contribute to an immunosuppressive TME. PhenoCode™ Signature T Cell Status Panel (CD8, CD4, CD20, FoxP3, PD-1) allows for identification of distinct T Cell subsets and effector functionality status. Map additional phenotypes by adding a 6…

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