Derivitization Reagents Products & Reviews

SELECTRA-SIL® Derivatizing Reagents SELECTRA-SIL® is an extensive line of derivatizing reagents manufactured by UCT at its facility in Bristol, PA. Our reagents are designed to increase molecular weight, lower boiling points, and create a more specific ion for compounds intended for gas chromatography and GC/MS. SELECTRA-SIL® Derivatizing Reagents Benefits: Improved chromatographic resolution - increased volatility - red…

Supelco provides high quality derivatization reagents for silylation.Silylation is the most widely used derivatization technique. Functional groups that present a problem with gas chromatogaphy detection - hydroxyl, carboxylic acid, amine, thiol, phosphate - can be derivatized by silylation reagents. Silylation involves replacement of the acidic hydrogen with an alkylsilyl group, for example, -SiMe3.Silylation derivatives are…

Supelco provides high quality derivatization reagents for acylation.Acylation, an alternative to silylation, allows the conversion of compounds with active hydrogen such as -OH, -SH, and -NH into esters, thioesters and amines, respectively. A very popular example of this method is the insertion of perfluoracyl groups to enable electron capture detection (ECD). Carbonyl groups adjacent to halogenated carbons enhance the ECD res…

Supelco provides high quality derivatization reagents for akylation and esterification.Alkylation is the replacement of the active hydrogen in R-COOH, R-OH, R-SH, R-NH, R-NH2, R-CONH2, R-CONH-R′ with an alkyl group, or sometimes an aryl group.Esterification is the first choice for derivatization of carboxylic acids and other acidic functional groups. Acids are reactive compounds, and are too polar to be well separated by gas c…