SPE Sorbents Products & Reviews

Conversion of cartridge-based methods to an automation friendly 96-well format has never been easier or faster. The same trusted silica-based sorbents in Bond Elut cartridge products are now available in the streamlined Bond Elut 96-well plates. Bond Elut 96 components are specially formulated to offer superior cleanliness, flow reproducibility, and reliability.

Bond Elut PRS is a strong cation-exchange sorbent that is also relatively high in polarity. With no appreciable degree of hydrophobicity, in nonpolar solvents, PRS is capable of polar and hydrogen bonding interactions. Due to the very low pKa of PRS, it is recommended for weaker cationic species, such as pyridinium compounds.

Evolute WCX is a mixed-mode weak cation exchanger, developed for extraction of strongly basic analytes and quaternary amines from aqueous samples. These analytes are typically found in pesticides and provide analytical scientists with the ability to extract pesticides from diverse matrices ranging from ground water to blood samples.

These cartridges are designed to meet large volume, real world samples. The frits and sorbent bed resist plugging, the format fits several types of manual and automated extraction systems. Various bonded phases available including C18, C8, DVB, & graphitized carbon black.

Robust, Accurate Polymeric Solid Phase Extraction (SPE) Products

Graphitized Non-Porous Carbon  

Available retention mechanisms include reversed phase, ion exchange, normal phase and mixed mode

Strata-X Drug B and N Solid Phase Extraction (SPE) sorbents are designed and quality control tested for basic and neutral drugs of abuse analysis, respectively. The sorbents are QC tested using drug probes from urine samples so that you can have confidence in your results. The sorbents also do not require conditioning/equilibrating steps, saving both time and solvent.

Bond Elut C18 is the most hydrophobic, bonded silica sorbent available in the Bond Elut range. It is the most popular SPE sorbent because of its extreme retentive nature for nonpolar compounds. C18 is generally regarded as having the broadest spectrum of retention among bonded silica sorbents, since it retains most organic analytes from aqueous matrices. 

Bond Elut PSA is an alkylated amine sorbent that contains two different amino functionalities, one secondary and one primary. This gives a slightly higher pKa and ionic capacity compared to Bond Elut NH2. PSA has a significantly higher carbon load than most amino functional sorbents and thus is a better choice for polar compounds, which retain too strongly on Bond Elut NH2.

“QuEChERS” (Quick, Easy, Cheap, Effective, Rugged, and Safe) - Supel™ QuEPSA/C18 Tube, pack of 100, suitable for 2007.01 per AOACDispersive SPE (dSPE), often referred to as the "QuEChERS" method, is an emerging sample prep technique that is becoming increasingly popular in the area of multi-residue pesticide analysis in food and agricultural products. In dSPE, food/agricultural samples are first extracted with aqueous miscibl…

Bond Elut AccuCAT cartridges are mixed bed SPE cartridges consisting of a strong cation exchange (SCX) and a strong anion exchange (SAX) sorbent packed into one bed. AccuCAT is effective for the extraction of acidic, basic, and neutral analytes from urine and other biological samples. AccuCAT is particularly effective for catecholamine extraction from biofluids.

Alumina, like silica, is an extremely polar sorbent. The alumina surface tends to be slightly more stable under high pH conditions than unfunctionalized silica. The small particle size of the Bond Elut Alumina range ensures high extraction efficiency even when small bed masses are used.

Due to the methyl group and subsequent low carbon load, Bond Elut C1 is the least retentive of all alkyl group bonded phases for nonpolar compounds. However, due to the extensive endcapping of this sorbent to mask polar silanol activity, retention, and elution of polar and multifunctional analytes can still be achieved.

Bond Elut C18 OH is a nonendcapped version of the octadecyl bonded phases that enables the silanols on the silica surface to be more active. This low-load C18 has well-controlled silanol activity that permits the fractionation of metabolites and enhances retention of basic compounds compared to an endcapped C18. The pore size makes it a good choice for peptide extraction.

Bond Elut C2 is a fairly nonpolar sorbent because of the short chain length of the functional group. C2 is often used during the process of method development if analytes are retained too strongly on a C8 or C18 phase. The polarity of C2 is slightly lower than a cyano phase for polar interactions.

Bond Elut C8 is very similar in property to C18, but is not as retentive for nonpolar compounds due to its shorter hydrocarbon chain and therefore reduced carbon loading. C8 is an excellent replacement for C18 when analytes are too strongly retained for effective elution. 

CBA is a midpolarity sorbent and weak cation exchanger (pKa 4.8). It can be used with a wider range of counterions than lower pKa sorbents like SCX, and will demonstrate easier elution of quaternary amine functionalized analytes.

Bond Elut Cellulose columns utilize a pure microgranular cellulose powder that is packed between two, 20 µm polyethylene frits. The cellulose phase is very stable over a wide pH range and contains an extremely low metal content (Fe and CU content less than 5 ppm). 

The Bond Elut Certify extraction cartridge utilizes a packed bed consisting of a special, nonpolar C8 sorbent and a strong cation exchanger (SCX). Certify is most commonly used to extract basic (cationic) drugs from urine and blood, but it is also very effective for extracting a wide range of compounds from a diverse number of aqueous matrices.

Bond Elut Certify II was developed specifically for the rapid and effective extraction of acidic drugs and metabolites from urine and other biological matrices. Certify II is a mixed-mode cartridge packed with nonpolar C8 and strong anion-exchange (SAX) sorbent. It has been optimized for acidic drugs, such as 11-nor-delta-9-tetrahydrocannibinol-carboxylic acid, salicylic acid, ibuprofen, acetaminophen, and other compounds tha…

Bond Elut CH is a midpolarity sorbent that exhibits unique selectivities for certain analytes. When employed as a nonpolar sorbent, CH has the approximate polarity of a C2 sorbent. Bond Elut CH is often a good choice when nonpolar sorbents, such as C18, C8, or C2, do not provide the desired selectivity.

A medium polarity sorbent with many uses, Bond Elut Cyano (CN) is ideal for applications in which extremely nonpolar compounds would be irreversibly retained on high carbon load sorbents, such as C8 and C18. This endcapped version of the cyano sorbent is best utilized when extracting analytes from an aqueous matrix.

Bond Elut DEA bears some resemblance to Bond Elut NH2 in its properties, but with a slightly lower capacity as an anion-exchange sorbent. DEA has a moderately nonpolar character due to the alkyl side chains on the amino functionality. These groups still afford a medium level of polarity, higher than C8, but less polar than C2 or CN-E.