Characterizing of the Natural Product Goldenseal Using CORTECS 2.7 µm Columns and ACQUITY QDa Detection

In this application note, five different sources of Goldenseal, which span four different manufacturers, two different parts of the plant, and two different formulation matrices are analyzed. This variety of sources was tested to determine the differences between each sample and if there were any compounds common to all the tested sources. Each sample was analyzed using a CORTECS C18+, 2.7 µm, 3.0 x 50 mm Column on an Alliance HPLC System with both UV and an ACQUITY QDa Detector in order to get fast and reliable mass data for peaks present in the sample, providing additional and crucial information for the characterization of the natural products.