Chiral Purification of Volatile Flavors and Fragrances by SFC

In this application note, linalool and terpinen-4-ol were used to demonstrate the chiral purification capabilities of SFC for volatile flavor and fragrance compounds. First, a recovery study was performed by collecting the enantiomers from (±)-terpinen-4-ol and (±)-linalool standards. These compounds were then enantiomerically purified from lavender and tea tree essential oils. Stacked injections and fast chiral separations reduced the time required for the enantiomeric purification of flavor and fragrance compounds.