CHO Cells Stably Expressing Voltage Gated Potassium Channels Tested on the QPatch Platform

This application data shows data from CHO cells stably expressing K_V1.5 tested on the QPatch platform. The voltage gated potassium channel K_V1.5 is a homotetrameric protein present in the heart. It is a delayed rectifier, participating in the early phase of the heart action potential. Experiments were conducted to evaluate the IV-relationship of K_V1.5 as well as dose-response for inhibitors. The response of K_V1.5 to a known blocker was also tested.