Determination of Drug-to-Antibody Ratio for Antibody-Drug Conjugates Purified from Serum

Antibody drug conjugates (ADCs) are used to create high local concentrations of cytotoxic drug at a specific target, with differing drug-to-antibody ratios (DARs). The DAR needs to be monitored closely, and this study demonstrates Agilent's complete ADC DAR determination solution.