How to freeze and store COVID-19 convalescent plasma

With the COVID-19 pandemic affecting lives across the world, clinical trials have been steadily on the rise. One of the forerunners in these trials is the convalescent plasma (CP) therapy, involving transfusion of plasma from the COVID-19 recovered patients. As this therapy involves the use of a temperature sensitive product human plasma, the ability to store it at the mandated temperature is critical to serve the therapeutic purpose.

This paper delves into the history of CP, some of its storage protocols, and highlights freezing and storage solutions that preserve the best quality of plasma.