Improved Throughput and Performance for the USP Propranolol Hydrochloride Assay using a KinetexR 2.6 µm C8 Core-Shell Column

The benefits of the new Kinetex core-shell C8 phase column are demonstrated in this note by applying it to methods requiring the use of a C8 (USP L7) column. The application of this technology to the USP assay for propranolol hydrochloride is shown to reduce analysis time while meeting the system suitability requirements for this USP monograph.