Targeting protein-protein interactions (PPIs): Identifying PPI inhibitors for novel therapeutics
Dr. David Andrews, AstraZeneca, discusses the future of small-molecule drug discovery for PPIs
Dr. David Andrews, AstraZeneca, discusses the future of small-molecule drug discovery for PPIs
With this addition, researchers can more easily screen for small molecule modulators of cGAS
BIOTAQ™ is widely used by molecular biologists that have come to depend upon the robust performance of this reagent. BIOTAQ is a highly purified thermostable DNA polymerase offering very high yield over a wide range of PCR templates (Fig. 1), and is the ideal choice for most assays. BIOTAQ is a robust preparation and consistently delivers high yields with minimal background. BIOTAQ possesses 5´-3´ exonuclease activity and leav…
TEST PRESENTATION HYDRAGEL von WILLEBRAND MULTIMERS kit is designed for the detection of abnormalities in the VWF multimers distribution related to a hemorrhagic diathesis. The test allows to assess the overall size distribution of von Willebrand factor multimers in human plasma using agarose gel electrophoresis and immunofixation, with the semi-automated the HYDRASYS 2 instrument. HYDRAGEL von WILLEBRAND MULTIMERS assay pr…
The PAXgene® Blood RNA Tube is intended for immediate stabilization of intracellular RNA, thereby yielding accurate and reproducible gene expression data. It is part of the PAXgene Blood RNA System that integrates the key steps of whole blood collection, intracellular RNA stabilization, and RNA purification. The PAXgene Blood RNA Tube contains a proprietary reagent for stabilization of intracellular RNA immediately upon col…
The AltoStar® Automation System AM16 is a robotic pipetting workstation used for sample purification and PCR setup controlled by the AltoStar® Connect software. It is intended to be used in combination with the AltoStar® Purification Kit 1.5, the AltoStar® Internal Control 1.5 and altona Diagnostics PCR kits for automated purification of nucleic acids and automated assay setup for in vitro diagnostic purposes. The AltoSta…
Zebron ™ ZB-XLB-HT is a phenyl-si-arylene bonded phase that can withstand temperatures up to 400˚ C, enabling analyses of compounds with high molecular weights and boiling points. The Zebron Inferno non-metal columns are stable at high temperatures due to proprietary coating and binding technologies, providing long lifetime, low bleed and low activity. They are ideal for analyses in environmental, food and beverage, pharmaceut…
Charge detection mass spectrometry adds new value to traditional mass spectrometry in detecting larger molecules such as coronaviruses.
The ForceRobot ® 400 BioAFM incorporates a number of unique force spectroscopy innovations to measure forces at the single-molecule level. As forces play a crucial role in molecular mechanisms, such as recognition and signaling, this BioAFM is uniquely suited for emerging life science research. It enables the quantification of the mechanical strength of individual molecular bonds and the characterization of the force-dependen…
The Ceres Nanosciences Nanotrap® Protein particles utilize affinity capture and size exclusion to attract and bind low abundance proteins, while excluding unwanted high abundance and high molecular weight interfering molecules
The Ceres Nanosciences Nanotrap® Protein particles utilize affinity capture and size exclusion to attract and bind low abundance proteins, while excluding unwanted high abundance and high molecular weight interfering molecules.
The Ceres Nanosciences Nanotrap® Protein particles utilize affinity capture and size exclusion to attract and bind low abundance proteins, while excluding unwanted high abundance and high molecular weight interfering molecules.
Professor Joon Won Park is head of the lab at POSTECH aims to utilize the high sensitivity of AFM for applications in medical diagnostics
Growing menu of assays allow for rapid turnaround of results with a more efficient workflow
The collaboration aims to identify novel small molecule cMET inhibitors for non-small cell lung cancer
Guest editor Dr. R.P. Iyer looks at how the power of nucleic acid technology is being used to defeat cancers, viral infections and inflammatory diseases
Read how GSK’s Method Innovation team is evaluating new technologies to drive efficiency in biopharma molecule development, in this exclusive interview
Cresset and Elixir to preview Torx™ at key European events for medicinal chemists