The cost of drug discovery continues to rise while the output of new NDAs continues to fall. Consequently it has never been more important to address attrition rates in drug discovery and development. Early indication of toxicity in a molecule or lead family means that discovery resources can be directed either at other chemical series if these are available or towards ‘breeding’ out undesirable properties. Gentronix and Apred…
R&D Human IL-1 beta/IL-1F2 Quantikine ELISA Kit - Human IL-1 beta/IL-1F2 Immunoassay for the quantitative determination of human interleukin 1 beta (IL-1 beta) concentrations in cell culture supernates, serum, and plasma. The Quantikine Human IL-1 beta ELISA is a 3.5 - 4.5 hour solid phase ELISA designed to measure IL-1 beta in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human IL-1 be…
R&D Human IFN-gamma Quantikine ELISA Kit - Human IFN-gamma Immunoassay for the quantitative determination of human interferon gamma (IFN-gamma) concentrations in cell culture supernates, serum, and plasma. The R&D Quantikine Human IFN-gamma Immunoassay is a 4.5 hour solid phase ELISA designed to measure IFN-gamma levels in cell culture supernates, serum, and plasma. The Quantikine ELISA contains E. coli-expressed recombinant…
World's First Product Containing a Metabolite MRM Database to Support Triple Quadrupole Gas Chromatograph Mass Spectrometers. Metabolite analysis uses exhaustive measurements of the metabolites in living organisms to comprehensively investigate the phenomena of life based on changes in metabolite components. This product was developed to support more accurate and efficient metabolomic analysis by GC/MS and GC/MS/MS. GC/MS Me…
iCell® Neurons, derived from human induced pluripotent stem (iPS) cells, provide a unique in vitro system for preclinical drug discovery, neurotoxicity testing, predictive disease modeling, and basic cellular research. A better and more biologically relevant alternative to current cell models, iCell Neurons offer researchers access to commercial quantities of high quality, highly pure human neurons that possess typical phenoty…
R&D Human G-CSF Quantikine ELISA Kit - Human G-CSF Immunoassay for the quantitative determination of human granulocyte colony stimulating factor (G-CSF) concentrations in cell culture supernates, serum, and plasma. The R&D Quantikine G-CSF ELISA is a 3.5 - 4.5 hour solid phase ELISA designed to measure G-CSF in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant human G-CSF and antibodies rai…
R&D Human IGF-I Quantikine ELISA Kit - Human IGF-I Immunoassay for the quantitative determination of human insulin-like growth factor I (IGF-I) concentrations in cell culture supernates, serum, and plasma. R&D Systems Quantikine ELISA Kits are complete and ready-to-use. Immunoassays are available for measuring a range of molecules including cytokines, chemokines, growth factors, proteases, and more. The R&D Quantikine Human I…
Extract and label proteins from extremely limited sample sizes The first commercially available nanoscale buffer kit for antibody arrays Minimal background for high signal-to-noise ratios Optimized for use with the Clontech™ Ab Microarray 500 Kimberly Milner and Dmitry Bochkariov, Ph.D. The Clontech™ Antibody Array Nanoscale Buffer Kits designed for those who have limited amounts of sample and want to assay hundreds…
Your busy life science laboratory demands performance and flexibility — count on the Thermo Scientific™ BioMate 3S UV-Visible spectrophotometer to deliver. With stray light and noise specifications comparable to instruments two or three times the price, the new, compact Thermo Scientific BioMate 3S saves you valuable bench space. The BioMate 3S offers pre-programmed assay methods for nucleic acid and protein concentration as…
R&D VEGF -Recombinant Human VEGF 165R Protein Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. Specifications and Use for R&D VEGF 165RSource of R&D VEGF• A DNA sequence encoding the 165 amino acid residue variant of human VEGF (Leung, D.W. et al., 1989, Science 246:1306) was expressed in…
R&D Systems - Recombinant Human HGF (NS0-expressed)HGF, also known as Hepatopoietin A, was initially identified as a potent mitogen for hepatocytes in primary culture. Subsequently, HGF was also shown to be mitogenic for a variety of cell types including endothelial and epithelial cells, melanocytes, and keratinocytes. Specifications and Use of R&D HGFSource of R&D human HGF • A DNA sequence encoding the 728 amino acid residu…
The Gass-less GC is an Educators best friend. It needs no gases thanks to it's CCD detector. It come with free software and classroom experiments all for under 5K. Our 310 Gas-less Educational GC system is ideal for undergraduate chemistry classes where the principles of gas chromatography are demonstrated on the same equipement students will encounter in industry. The Gas-less Educational GC includes a built-in "whisper quie…
The Gass-less GC is an Educators best friend. It needs no gases thanks to it's CCD detector. It come with free software and classroom experiments all for under 5K. Our 310 Gas-less Educational GC system is ideal for undergraduate chemistry classes where the principles of gas chromatography are demonstrated on the same equipement students will encounter in industry. The Gas-less Educational GC includes a built-in "whisper quie…
Transform your laboratory Ensure your lab remains competitive by choosing and using a future-proof lab solution, designed for the cloud and ready for artificial intelligence. Clinisys Laboratory Solutions™ speed up workflow and simplify processes across end-to-end lab operations within a wide range of industries and sectors. Stay ahead of the competition: Work intuitively and increase team productivity. Make better…
iCell® Endothelial Cells, interior surface blood vessel cells derived from human induced pluripotent stem (iPS) cells facilitate vascular-targeted drug discovery, tissue regeneration, and other life science research. iCell® Endothelial Cells exhibit characteristic endothelial gene and protein expression (e.g., CD31, CD105, CD144, ZO-1, and von Willebrand Factor) and endothelial cell functions (e.g., tubular formation, acetylat…
Adaptable Microplate Solution for Custom ELISA Applications. BRANDplates® Strip Plates are especially suited for laboratories designing custom ELISA applications, or desiring increased flexibility in their ELISA application. To ensure the effective binding of a wide range of antigens or antibodies to the microplate surface, the strip plates are available in two treatment types: pureGrade™ or immunoGrade™. The pureGrade™ plate…
KAPA Library Quantification Kits contain all the reagents needed for the accurate, reliable and reproducible qPCR-based quantification of NGS libraries prior to pooling for capture or flow cell amplification. Kits contain KAPA SYBR® FAST qPCR Master Mix, optimized for high-performance SYBR Green I-based qPCR. The engineered KAPA SYBR FAST DNA Polymerase contained in the Master Mix amplifies GC- and AT-rich DNA fragments of…
Making a dedicated and expensive GC-TOF-MS used infrequently for just a few samples a thing of the past. The GC-APCI II source enables GC coupling to any Bruker TOF or QTOF, trap or FTMS system originally designed for LC coupling.With its second generation GC-APCI source, Bruker offers the greatest flexibility and highest performance with a combined GC frontend and high-resolution MS system for confident ID of unknown compoun…
ToxCount™ provides a two wavelength cell viability assay based on determination of live and dead cells. The assay uses fluorescent dyes that measure permeability of the plasma membrane of dying cells and the ability of living cells to retain intracellular esterases, respectively. Live cells are distinguished by the presence of ubiquitous intracellular esterase activity, determined by the enzymatic conversion of the non fluores…
The quartz crystal microbalance (QCM) is a variant of acoustic wave microsensors that are capable of ultrasensitive mass measurements. Under favorable conditions, a typical QCM can measure a mass change of 0.1-1 ng/cm2. QCM oscillates in a mechanically resonant shear mode under the influence of a high frequency AC electric field which is applied across the thickness of the crystal. Figure 1b shows an edge view of a QCM crystal…
Innovative cell culture plates and inserts for co-culture, migration/invasion assays, 3D tissue preparation and more. The BRANDplates Insert System, co-developed with the Fraunhofer Society, offers an innovative expansion of the BRAND cell culture product line. The new Insert system consists of 24-well standard and 6-well specialized plates and strips of hanging cell culture inserts for applications such as co-culture,…
R&D Stem Cell Kits and Panels Research in developmental biology has led to the discovery of several types of stem cells, including embryonic stem (ES) cells, embryonic germ cells, and adult stem cells. Techniques and reagents developed for the in vitro culture, manipulation and characterization of stem cells provide unprecedented opportunities to study embryology and develop disease treatments. R&D Systems offers the follow…
DATAN 3.0OverviewWith DATAN 3.0 characterization of chemical equilibria and chemical reactions becomes easy. DATAN exploits the great advantage of collecting entire spectra and even higher order experimental data when studying chemical samples. Behind a user friendly interface state of the art algorithms, several of which are proprietary to MultiD, are used to extract chemical information about the samples with minimum assumpt…
SimGlycan™ Software (a product of PREMIER Biosoft International) predicts the structure of a glycan from the MS/MS data acquired by AB SCIEX mass spectrometers. It facilitates the study of glycosylation and post translational modifications. The software works directly with *.t2d and *.wiff data generated from AB SCIEX instruments, including the 4800 Plus MALDI TOF/TOF™ Analyzer, 4000 QTRAP® System, and QSTAR® Elite System. * M…
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