ACQUITY UPC2 Trefoil and Torus Columns
ACQUITY UPC2 Column Technology for Chiral and Achiral Separations. ACQUITY UPC2 Trefoil™ 2.5 µm Columns are uniquely designed for the ACQUITY UPC2 System. Selectivity and speed for chiral separations Reduce method development time Based on modified polysaccharide-based stationary phases for broad-spectrum chiral selectivity. ACQUITY UPC2 Torus™ Columns simplify the method development process with four completely new…
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Clinical Applications
Very nice separation chromatography for both polar and non polar smaller molecules compared to both liquid and gas chromatography.
Review Date: 30 Nov 2021 | Waters
For separation of polar small-molecule analytes in complex matrices via SFC
We have been very pleased with the chromatographic performance of the Torus range of columns, and have so far evaluated all four (Diol, 2-Pic, DEA, 1-AA) for the separation of a range of polar and non-polar metabolites by SFC. These columns offer dramatically (upwards of 40% when compared to previously available SFC columns) improved peak capacities and resolution for polar compounds in particular, and show markedly less tailing for basic compounds in the presence of methanolic co-solvents. We have also observed substantial improvements in reproducibility and robustness for high-throughput applications. Waters has been very helpful in recommending these columns for our applications, and there is no question that these columns are a wise purchase for any laboratory moving into the area of SFC.
Review Date: 23 Apr 2015 | Waters
ACQUITY UPC2 Column Technology for Chiral and Achiral Separations.
ACQUITY UPC2 Trefoil™ 2.5 µm Columns are uniquely designed for the ACQUITY UPC2 System.
- Selectivity and speed for chiral separations
- Reduce method development time
- Based on modified polysaccharide-based stationary phases for broad-spectrum chiral selectivity.
ACQUITY UPC2 Torus™ Columns simplify the method development process with four completely new and innovative 1.7 µm chemistries for convergence chromatography.
- Excellent peak shape and robustness while reducing or eliminating the need for additives
- Four column chemistries provide added selectivity for a wide range of compounds
Column Specifications:
- Technology: Torus, Trefoil
- Chemistry: 1-AA, 2-PIC, DEA, DIOL, AMY1, CEL1, CEL2
- Particle Size: 1.7, 2.5 µm
- Pore Size: 130 Å
- Length: 50, 75, 100, 150 mm
- ID: 2.1, 3.0 mm
