Circular RNAs (circRNAs) Services
Comprehensive circRNA services including design, circularization (e.g., ribozyme/intron-mediated), purification, and analytics to deliver stable, translation-competent RNA with improved durability—supported by process development for research and translational programs.
Circular RNAs (circRNAs) Services
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Creative Biolabs supports circular RNA (circRNA) design, synthesis, and characterization to enable stable, translation-competent constructs with improved durability over linear RNA for research and therapeutic use.
Services cover intron-mediated or Ribozyme-assisted circularization, sequence/UTR optimization, purification, and performance analytics including expression, stability, and innate immune activation profiling.
Key Features / Benefits
- Multiple circularization strategies (IVT/Ribozyme/IMC) and sequence optimization
- Analytical testing for expression, stability and innate immunity
- Optional chemical/base modifications and capping/UTR tuning
- Process development and documentation for scale-up
Relevant Applications
- Durable expression studies vs linear mRNA
- In vitro/in vivo evaluation of circRNA payloads
- Platform assessment for therapeutic research programs
