Custom Formulation & Conjugation Solutions
Tailored formulation and conjugation for nucleic acids and biologics, covering LNPs and alternative carriers, ligand-directed strategies (e.g., GalNAc), and full characterization and process development to enhance stability, targeting, and potency with documentation for scale-up and regulatory needs.
Custom Formulation & Conjugation Solutions
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Creative Biolabs provides custom formulation and conjugation solutions for nucleic acid and biologic therapeutics, including LNP systems, polymeric carriers, and ligand-directed conjugates to improve stability, targeting and potency.
Offerings include excipient screening, process development, characterization (size, PDI, zeta, EE), stress testing, and conjugation to antibodies/peptides (e.g., GalNAc, AOC/ARC concepts).
Key Features / Benefits
- LNP and alternative carriers with process development and scale-up
- Comprehensive characterization (size, PDI, zeta, loading, stability)
- Ligand-directed conjugation (GalNAc, antibody/peptide) and analytics
- Documentation for tech transfer and regulatory packages
Relevant Applications
- Delivery optimization for siRNA/ASO/mRNA/DNA payloads
- Targeted delivery via GalNAc, antibodies or peptides
- Preclinical formulation selection and comparability studies
