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DNase I (RNase-free)

New England Biolabs Inc.M0303SAvailable: Worldwide

DNase I, (RNase-free) is an endonuclease that nonspecifically cleaves DNA to release di-, tri- and oligonucleotide products with 5´-phosphorylated and 3´-hydroxylated ends (1,2). DNase I acts on single- and double-stranded DNA, chromatin and RNA:DNA hybrids.

New England Biolabs Inc.

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Average Rating 5.0

Application Area:

Digests DNA in RNA purification

We found the NEB DNase I to be as effective at a lower price than our previous supplier.

Review Date: 14 Jan 2020 | New England Biolabs Inc.

DNase I, (RNase-free) is an endonuclease that nonspecifically cleaves DNA to release di-, tri- and oligonucleotide products with 5´-phosphorylated and 3´-hydroxylated ends (1,2). DNase I acts on single- and double-stranded DNA, chromatin and RNA:DNA hybrids.

  • Isolated from a recombinant source
  • Supplied with a 10X Reaction Buffer
  • Product source: An E. Coli strain that carries an MBP fusion clone of Bovine Pancreatic DNase I

DNase I (RNase-free) is ideal for:

  • Degradation of DNA template in transcription reactions
  • Removal of contaminating genomic DNA from RNA samples
  • DNase I footprinting
  • Nick Translation

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