Kolliphor P 188 Geismar
A polymeric multi-talent non-ionic polymer suitable for various pharmaceutical applications
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Can be used as surfactant, pore former, solubility enhancer, etc.
Formulation development, surfactant
The product is very effective in making different formulations. It's very hygroscopic and thus need to ensure the weight of the product does not include the weight of water, which can significantly alter your results.
Review Date: 28 Jul 2021 | BASF Pharma
Kolliphor® P 188 is supplied as white to slightly yellowish, coarse grained powder with a waxy consistency. It is freely soluble in ethanol, freely soluble in water (opalescent solution), and is insoluble in diethyl ether, paraffin and fatty oils.
Benefits
- HLB value >24
- It used as wetting agents, as emulsifiers and solubilizers
- It improves the solubility, absorption and bioavailability of low-solubility actives
- Aqueous solution containing more than 20% concentration are themoreversible viscosity
- Also used for hot-melt and spray-drying processes
- Poloxamers are non-ionic and less irritating upon application
