NCI-H295R
Human Adrenal gland carcinoma cell line. Frozen cryovial. 2 Mio. cells/ml.
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Human Adrenal gland carcinoma cell line NCI-H295R
Organism: Homo sapiens (human)
Ethnicity: Black
Age: 48 years
Gender: Female
Tissue: Adrenal gland
Morphology: Epithelial
Cell type: Adrenocortical carcinoma
Growth Properties: Monolayer, adherent
Description: NCI-H295R was adapted from the NCI-H295 pluripotent adrenocortical carcinoma cell line established by A.F. Gazdar and associates (1990) from a carcinoma of the adrenal cortex. The original cells were adapted to a culture medium which decreased the population doubling time from 5 days to 2 days. While the original cells grew in suspension, the adapted cells were selected to grow in a monolayer. This cell line retains the ability to produce adrenal androgens. It is responsive to angiotensin II and potassium ions.
Subclone: This NCI-H295R cells belong the the sub-group S1, see the publication by Wang et al. 2012.
