ReadyToProcess WAVE™ 25 Rocker
The ReadyToProcess WAVE™ 25 rocker features integrated temperature sensors and load cells, designed for convenient handling and control of cell cultures up to 25 L. A filter heater is delivered with the system.
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A tool for cell culture that can be use for regenerative medicine.
A tool for cell culture that can be used in vaccines and monoclonal antibodies production
Cytiva WAVE bioreactor system is easy to use, reduces time for cell culturing, and gives the highest numbers of cell count.
Review Date: 29 Sept 2022 | Cytiva
Well worth purchasing.
Protein expression
The Wave is a very simple system to use. I've used it since the very beginning of it's existence and am still enamoured of it. Easy, simple, effective, Excellent oxygen transfer..
Review Date: 26 Jan 2018 | Cytiva
I like the Wave reactor and ease of use
I say, go for it. Get rid of the steel reactors and go to the efficiency of the Wave reactor. Various companies make the bags for them, so you aren't hampered by expensive pricing disposable bags.
Review Date: 20 Mar 2015 | Cytiva
Recombinant Protein Manufacturing
The WAVE bioreactor systems from GE represent an excellent option for bench-scale bioreactor systems when ease-of-entry and/or fast batch turnaround times are required. While not as automated and tuneable as many similarly priced glass/stainless systems, for routine culture of CHO or similar cell lines they are stable, robust and relatively trouble-free. They are an excellent choice for those looking for a disposable, easy to use and dependable platform for small-to-medium scale protein expression.
Review Date: 26 Jun 2014 | Cytiva
Cell Culture
It is very easy to use for insect , mammalian and Cho cell lines. The tech staff is not too quick to respond to troubles. I've used it since it was invented. Now the GE bought the company, I recommend buying the bags at different companies, like Charter Medical, for instance. GE has priced the bags very high.
Review Date: 15 Apr 2014 | Cytiva
The ReadyToProcess WAVE™ 25 rocker features integrated temperature sensors and load cells, designed for convenient handling and control of cell cultures up to 25 L. A filter heater is delivered with the system.
Mixing and gas transfer
The adjustable rocking parameters are speed, angle, and motion. The parameter settings, in combination with the cell culture volume, affect the mixing and gas transfer rate in the Cellbag™ bioreactor. The speed parameter determines the number of rocking cycles per minute, and the angle parameter relates to the tray’s degree of tilting at the turning points. The motion parameter determines the acceleration profile.
Temperature control
Reliable, efficient, and evenly distributed heating is provided by the tray heater plate. The temperature measurement is managed by sensors integrated in the rocker base unit. For an accurate, stable, and fast temperature control, the heater power output is automatically adjusted based on the Cellbag™ bioreactor size and the medium volume as measured by the internal scale. When used in dual mode, temperature is controlled independently in the two separate Cellbag™ bioreactors.
Weight measurement
Load cells integrated in the rocker provide accurate and continuous weight measurement of the culture and eliminate the need for external scales. The load cells communicate with the system control function for proper medium handling and for tailored regulation of pH and temperature. The weight measurement functionality is also used for automatic calibration of the pump when used in perfusion culturing. Adjustable feet enable equal weight distribution between the load cells also on non-level surfaces, for increased precision of the weight measurement.
Data storage and communication
All run data and control parameters are stored on two independent, mirrored solid state drives integrated in the rocker. After a run, data is stored in a UNICORN™ database on an external computer. For facilitated integration into a larger manufacturing operation, the rocker also contains software to enable direct communication with the system via an open platform communication (OPC) link.
Trays and lids
Trays are available in three different sizes for culturing of up to 5 L, 10 L, and 25 L. The trays are easily attached to the rocker when in the tilt position. A snap lock mechanism allows Cellbag™ bioreactors to be correctly installed and rapidly changed. To protect light-sensitive components of the culture medium and to prolong the life of the optical sensors, lids are available for all tray sizes. The ergonomic rocker design makes handling convenient and easy. The ability to handle the bioreactor in a tilt position facilitates sampling and harvest. The wide top opening facilitates for the user to interact with the culture without removing the lid.
- Ergonomic design makes handling convenient and easy
- Minimal footprint facilitates placement when space is limited
- Ability to handle the bioreactor in a tilt position facilitates sampling and harvest
- Operation in single or dual culture mode
- Reliable temperature measurement from integrated sensors
- Accurate weight measurement from integrated load cells
