Scherzo SS-C18 Column
World’s first ODS column with anion and cation exchange.
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A great find for separating complex heterogenous mixes!
Chromatography
I found this mixed mode column to be INVALUABLE for the separation and analysis of compounds of mixes of heterogeneous nature. The combination of retention mechanisms [normal phase, reverse phase and strong anion and cation exchange] allows to vary several parameters [ionic strength, pH, % organic] to obtain the desired separation. Additionally, it is available in a broad range of lengths and diameters, enabling the user to apply it for preparative purposes. And as an added bonus, it comes in a beautiful wooden case, combining artsy presentation to its great separation performance!
Review Date: 8 Feb 2021 | Imtakt
The Scherzo family of columns is one of the most unique and versatile series of columns on the market today. These multi-mode columns utilize reversed-phase, cation, and anion exchange, as well as normal phase modes all on the same column, virtually eliminating the need for ion-pairing reagents. Ideal for the simultaneous analysis of polar and non-polar analytes from vitamins, to metabolomics saving time and resources.
- Polar and non-polar retention in reversed-phase conditions
- Multi-level retention without ion-pairing reagents
- Compatible with LC-MS
- Most unique selectivity of any HPLC column on the market today
- Wide range of method development possibilities
- Can simultaneous optimize organic, buffer, and pH gradients
- Anion exchange + cation exchange + reversed phase + normal phase
- Large amount of strong ionic ligands, effective for improved retention of zwitterions or weak ionic compounds
