Thermo Scientific™ SMART Digest™ Kits
Obtain high quality analytical results from protein digests by using Thermo Scientific™ SMART Digest™ Kits. A significant advance in sample preparation for biopharmaceutical and protein research, the kits provide fast and simple protein digestion with high reproducibility, high sensitivity, and high levels of data quality in a format that's compatible with automation. The SMART Digest Kits are a significant improvement over cu…
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Provide quick, robust and convenient application
Peptide map analysis using tryptic digests
The Smart Digest using immobilized trypsin provides a quick and convenient digestion tool for monoclonal antibodies (in 15-30 min). If full coverage is not a goal, no need for additional reduction/alkylation. Resulting peptide mixture can be used for peptide map analysis or glycosylation analysis focusing on glycopeptides. With post-digestion reduction/alkylation full coverage can be achieved.
Review Date: 31 May 2016 | Thermo Fisher Scientific
quick digestion of proteins
Ideal when looking at PTM's in the target proteins. Longer peptide generation protocols, that can be cheaper per sample, will inevitably introduce unwanted PTM's, especially oxidation of methionine that can interfere with downstream analysis. Not ideal for phosphopeptide analysis as the buffers lack phosphatase inhibitors.
Review Date: 29 Sept 2015 | Thermo Fisher Scientific
Obtain high quality analytical results from protein digests by using Thermo Scientific™ SMART Digest™ Kits.
A significant advance in sample preparation for biopharmaceutical and protein research, the kits provide fast and simple protein digestion with high reproducibility, high sensitivity, and high levels of data quality in a format that's compatible with automation. The SMART Digest Kits are a significant improvement over current in-solution protein digestion technologies, which are not reproducible, have poor sensitivity, and employ protracted methodologies not amenable to automation.
Features:
Easy and simple
- Significantly increased speed of sample processing.
- 3-step sample preparation.
- Easily automate entire protocol for high-throughput processing.
Reliable results
- Increased reproducibility over existing protocols.
- Higher sensitivity.
- Higher data confidence.
