rCPC

Our engineers designed the rCPC platform for pilot-scale purification tasks within a laboratory environment. It is ideal for all batch sizes, smaller or larger, or campaign type of research work, and continuous-batch production. To accommodate a user-friendly operation, RotaChrom offers a turn-key solution package for semi-automated solvent handling (preparation and recovery) upon request.
rCPC can be utilized as an at-line purification platform besides our industrial-scale purification unit. This means your separation needs can be executed in an orthogonal manner. A category of its own, the rCPC offers outstanding throughput, purity and yield, and does all that while remaining cost-efficiency.

Going beyond the general requirements, RotaChrom offers tailor-made system modifications, and does it while fulfilling any regulatory requirements you have to meet.

Pricing is based on the extent of the unique configuration and specific expectations.

RotaChrom has developed a revolutionary preparative purification method called Industrial Scale Centrifugal Partition Chromatography (iCPC). This novel system does not utilize any solid stationary phase (such as silica gel) to achieve precision molecular separation and is demonstrably superior to conventional liquid chromatographic techniques in terms of yield and purity. In addition, the iCPC platform has radically reduced the costs and number of steps associated with downstream method development for a diverse array of purification challenges.

Solid-liquid chromatographic methods used for purification, separation and extraction processes are effective and widely used throughout the chemical manufacturing industry. However, these methods are limited in available solvents and stationary phases, incur high costs attributed to spent materials and quickly fall off in performance when scaling to industrial volumes. While other liquid-liquid techniques like countercurrent distribution (CCD) are quick and effective for small lab or pilot-scale applications, it exponentially increases production times when scaling to larger volumes.

Innovations in Centrifugal Partition Chromatographic (CPC) technologies have brought this previously overlooked method into the public eye as a viable alternative or supplement to legacy preparative chemistry techniques. We offer a wide range of solutions to meet your business needs and help you boost your performance with our one-of-a-kind CPC technology at the heart of our rCPC and iCPC platforms.

Designed for pilot-scale purification tasks within a laboratory environment, rCPC is ideal for small or mid-sized batches, research campaigns and continuous-batch production. When utilized as an at-line purification platform with our industrial-scale purification unit, you can execute separation tasks orthogonally. To fulfill any regulatory or application design requirements you may have, we offer custom modifications to tailor your rCPC system exactly as you need it. As a pilot-scale solution, rCPC offers outstanding throughput, purity and yield while remaining cost-efficient.