Drug discovery > Pre-Clinical Development Products & Reviews

The ratio of Total to Intact IGFBP-4 concentration measured in individual subjects over time will help normalizes the IGFBP-4 variability between subjects and also increase the detection rate of increased PAPP-A activity in myocardial infarction subjects.

During pregnancy, PAPP-A is produced in high concentrations by the trophoblast and released into maternal circulation. In addition to trophoblasts, PAPP-A expression has been reported in various tissues, including endometrium, testis, atherosclerotic arteries, kidney, bone, colon, and other adult and fetal tissue.

Activin B exhibits a wide range of biological activities, including regulation of embryogenesis, osteogenesis, hematopoiesis, reproductive physiology and hormone secretion from the hypothalamic, pituitary and gonadal glands.

The Glucagon Enzyme Linked Immunosorbent Assay (ELISA) kit provides materials for the quantitative measurement of Glucagon in human plasma and other biological fluids.

The picoPAPP-A enzyme linked immunosorbent assay (ELISA) kit is useful in detection at low concentrations of Pregnancy Associated Plasma Protein A for studies of non-pregnant physiological states, pregnancy, dysfunctions of placental formation, certain cancers, and cardiovascular disease

The Total hCG enzyme linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of Total hCG in biological fluids

The AFP enzyme-linked immunosorbent assay (ELISA) kit provides materials for the quantitative measurement of AFP in serum

The myelin basic protein (MBP) enzyme linked immunuosorbent assay (ELISA) kit provides materials for the quantitative measurement of MBP in cerebrospinal fluid

Pregnancy associated plasma protein-A2 (PAPP-A2) is a novel metalloproteinase identified as a homolog of PAPP-A in the metzincin superfamily of pappalysins. PAPP-A2 shares 46% sequence identity with PAPP-A. PAPP-A2 is a noncovalently linked dimer of two 220-kDa subunits. It exhibits robust proteolytic activity against IGFBP-5 and possibly also IGFBP-3.  PAPP-A2 is expressed in a wide range of tissues and is abundant in placent…

The Ansh Labs' Equine Anti-Müllerian hormone (AMH) enzyme-linked immunosorbent assay (ELISA) kit is the only AMH assay designed specifically for use in horses. Multiple validation studies have shown excellent distinction between castrated geldings and intact stallions. AMH is also an excellent tool in the evaluation of equine granulosa cell tumors (GCT) and cryptochordism.