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Supel™ Swift HLB SPE Cartridges

Merck

Supel™ Swift HLB is a polymeric stationary phase for solid phase extraction (SPE) prior to instrumental analysis. It has both hydrophilic and lipophilic functional groups for the extraction of a broad range of compounds from aqueous samples. It retains analytes having diff erent polarities and Log P values due to its hydrophilic and lipophilic balance (HLB) property.

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Fetal Bovine Serum

Merck

Fetal Bovine Serum (FBS) is the most widely-used growth supplement for cell culture, containing a complex mixture of biomolecules that includes growth factors, proteins, trace elements, vitamins and hormones for cell growth. Our extensive portfolio of FBS enables you to easily select the right FBS for your culture and criteria.

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ECMatrix

Merck

ECMatrix™ laminin substrates for culturing pluripotent stem cells (iPSCs) to promote in vivo–like morphology and simulate a more physiologically relevant environment for better intercellular interactions and better predictive cell models.

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Supel™ BioSPME 96-Pin Devices

Merck

Supel™ BioSPME 96-Pin Devices were developed to greatly improve upon the speed and simplicity plasma protein binding studies and other free analyte analyses.  Our technology offers a 3x faster workflow compared to rapid equilibrium dialysis based methods, is amenable to both automation and manual operation, and is a convenient universal 96-pin format compatible with standard 96-well consumables.  

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Sigma-Aldrich® CRISPR synthetic gRNAs

Merck

Sigma-Aldrich ® one-part sgRNA and two-part crRNA:tracrRNA systems accelerate genome editing with Cas9 protein, mRNA, or established Cas9 expressing cell lines. Our guides are compatible with a variety of delivery methods including microinjection, electroporation, and lipofection.

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Immuno-Oncology Cell lines by Sigma-Aldrich®

Merck

Merck's immuno-oncology cell lines are innovative research tools for biologics discovery and clinical development. These are the perfect cell-based assay tools you need for the entire drug discovery and clinical development process. Whether you need screening tools for CAR/TCR therapies and mAB development, target cells for efficacy testing, or potency assays for clinical development, Merck provides functional biologically-re…

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MISSION® shRNA Clones

Merck

The largest and most validated shRNA collection from the RNAi consortium (TRC). Merck's unique shRNA formats leverage the discovery potential of the trusted and proven TRC shRNA collection. When you partner with them, you gain access to their world class lentiviral production expertise and the formats and specifications for RNAi knockdown experiments at any scale.

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CRISPRi Libraries, Pools, and gRNAs

Merck

Nuclease-independent applications of CRISPR provide equal targeting specificity but instead of cutting, CRISPRi allows for targeted interference of gene function by delivering transcriptional repressor domains to a specific target sequence using modified dCas9 + gRNA complexes. Gene knockdown is complementary to CRISPR-KO and CRISPRa (activation) and has distinct advantages over existing loss-of-function strategies like RNAi.…

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