Drug discovery > Basic Research Products & Reviews

Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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Baculo Expression Vector pAc-kappa-Fc

PROGEN

Baculovirus cassette vector pAc-kappa-Fc for the expression of human, humanized or chimeric IgG(kappa) in insect cells and secretion of assembled antibodies into the supernatant. The vector derived from pAcUW51 is suitable for cloning of heavy and light chain Fab antibody gene fragments.

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Baculo Expression Vector pAc-lambda-CH3

PROGEN

Baculovirus cassette vector pAc-lambda-CH3 for the expression of human, humanized or chimeric IgG(lambda) in insect cells and secretion of assembled antibodies into the supernatant. The vector derived from pAcUW51 is suitable for cloning of heavy and light chain scFv antibody gene fragments.

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Baculo Expression Vector pAc-lambda-Fc

PROGEN

Baculovirus cassette vector pAc-lambda-Fc for the expression of human, humanized or chimeric IgG(lambda) in insect cells and secretion of assembled antibodies into the supernatant. The vector derived from pAcUW51 is suitable for cloning of heavy and light chain Fab antibody gene fragments.

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Human IgG / IgM Library Primer Set

PROGEN

PCR oligonucleotide primer sets consisting of 16  primers  for amplification and 16 primers  for cloning of human IgG and IgM heavy and light chain variable domain coding regions for generating universal, patient or antibody-specific scFv phage-display libraries. 

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Mouse IgG Library Primer Set

PROGEN

PCR oligonucleotide primer sets consisting of 25 primers for amplification and 25 primers for cloning of mouse IgG heavy and light chain variable domain coding regions for generating universal or antibody-specific scFv phage-display libraries.

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pOPE 101 Expression Vector

PROGEN

Cassette vector for the expression of functional recombinant single-chain Fv antibody fragments in Escherichia coli. Cloning of heavy and light chain variable domain genes of Fv antibody fragments selected from hybridomas, single B-lymphocytes or phage display libraries. Discover more about the hyperphage system here.

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Anti-p62 / SQSTM1 (C-terminus) guinea pig polyclonal, serum

PROGEN

The anti-p62 antibody is useful for research in ubiquitin-associated degradation and autophagy and for detection of neurofibrillary tangles in the brain of Alzheimer disease patients, in Parkinson diseases and various chronic liver diseases. Human p62 protein, present in intracytoplasmic inclusions is found in many tissues and cells, serving probably a common cellular signal transduction mechanism. Human 62 kD (p62) protein…

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IHC antibodies

PROGEN

A broad portfolio of >400 IHC antibodies used for research and diagnostics of >40 pathologies in 25 different organs and tissues.

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