Drug discovery > Basic Research Products & Reviews

The Agilent Seahorse XF Plasma Membrane Permeabilizer (PMP) is a proprietary reagent that permeabilizes intact cells in culture. It selectively targets the cellular plasma membrane while leaving the mitochondrial membrane intact. This selectivity enables the detailed characterization of key components in mitochondrial function including transporters, enzymes, and electron transport chain complexes.

Agilent Seahorse XF Hu T Cell Activation Assay Kit measures human (Hu) T cell activation response within several minutes of stimulation using Seahorse XF Analyzers. This is accomplished via measuring proton efflux rates (PER) associated with glycolytic pathway-dependent energy production, and is built on the principle that T cell activation is accompanied by a rapid switch in cellular energy production and intermediate demand…

The Agilent Seahorse XF Palmitate Oxidation Stress Test Kit provides validated reagents to measure long chain fatty acid oxidation (FAO) via assessing changes in oxygen consumption (OCR) in intact cells. The kit includes the XF Palmitate-BSA FAO Substrate, L-carnitine, etomoxir, as well as oligomycin, FCCP, and rotenone/antimycin A to determine the intrinsic rate and capacity of a cell to oxidize palmitate in the absence or l…

Agilent offers a new microplate product line to support cell culture and imaging. These high-quality polystyrene products provide superb optical clarity and comply with ANSI standards for compatibility with automated processing systems. TC surface treatment enhances cell attachment while the included lid maintains a sterile growth environment with low risk of cross-contamination. The product designs feature easy stacking, alp…

SureSelect Cancer CGP assay offers comprehensive genomic profiling for solid tumors. This pan-cancer NGS panel enables detection of somatic variants, including single nucleotide variants (SNVs), copy number variants (CNVs), insertions/deletions (indels), translocations (TLs), gene fusions, and the immuno-oncology biomarkers TMB (tumor mutational burden) and MSI (microsatellite instability).

The Cary 3500 Compact UV-Vis is a double beam spectrophotometer featuring new and unique measurement capabilities that can be deployed in regulated environments. The system performs ambient and temperature-controlled experiments with air-cooled Peltier temperature control, and it accurately analyzes low volume samples—providing in-depth analysis by collecting up to 250 data points per second. The xenon flash lamp—complete with…

Integration of the xCELLigence Real Time Cell Analyzer (RTCA) HT instrument with the BioTek BioSpa 8 automated incubator expands the screening throughput of your RTCA HT instrument to eight 384-well plates. Label-free high-throughput xCELLigence Real-Time Cell Analysis is ideal for screening viral mediated cytopathic effects (CPE), neutralizing antibodies, antibody-dependent cytotoxicity (ADCC), and compound mediated cytotoxi…

Designed for smaller studies, the SureSelect DNA Capture Arrays complement Agilent's in-solution SureSelect Target Enrichment System, which is designed for medium to large-scale NGS studies of tens through thousands of samples, including automated high-throughput workflows.

Agilent’s market leading SureSelect platform provides a complete portfolio of catalog and custom products, providing the flexibility you need from discovery to follow-up studies. Agilent’s custom solutions offer the only available method for target enrichment of RNA, allowing you to target your regions of interest using our free web portal SureDesign. Custom solutions are available for DNA and RNA target enrichment. • The only…

eArray is a web-based application that enables you to harness the flexibility of Agilents SurePrint oligo manufacturing technology in the creation of custom microarray designs and oligo libraries.  eArray, free to all registered users, allows you to create assays that are specific to your research needs. Create custom microarray designs for Gene Expression, microRNA, Model Organisms, CGH, ChiP-on-chip, and DNA Methylation.Crea…

The Agilent SurePrint G3 Human GE 8x60K Microarrays offer the same high sensitivity and accuracy provided by the earlier generation arrays but adds the benefits of extended coverage, greater throughput, and increased cost savings. The new SurePrint G3 Human GE 8x60K Microarrays and Human GE 4x44K v2 Microarrays are based on updated transcriptome databases for mRNA targets, while the SurePrint G3 arrays also include probes for…

The AllerGard™ ES (Energy Saver) NU-620 Animal Transfer Station is modeled after the Class II Biological Safety Cabinet design offering you the highest vivarium standard in the environmental, personnel and product protection for small animal cage changing procedures. Model NU-620 is an entirely mobile unit that can be outfitted with various ergonomic accessories to the meet the need of your facility's workflow. Uncompromise…

The AllerGard™ NU-621 is a singled-side Animal Transfer Station (ATS) that offers improved allergen protection through a dynamic air barrier of 75 fpm (0.38 m/s) through the front of the cabinet.

The NU-620M uses an impeller and HEPA filter in both the supply module at the top of the unit as well as in the exhaust module at the bottom to turn the work zone in between into a vertical “piston of air.”

The NU-620R uses an impeller and HEPA filter in both the supply module at the top of the unit as well as in the exhaust module at the bottom to turn the work zone in between into a vertical “piston of air.”

Cage changing is not the most glamorous of tasks, but it is an essential part of maintaining the integrity of your lab animals' results. The AllerGard™ ES (Energy Saver) NU-608 Class I Animal Waste Station minimizes the risk of exposure to allergens and animal infections for the technician handling low to moderate risk materials through HEPA filtration and an air barrier. HEPEX™ Zero Leak Airflow System NuAire’s propriet…

Consistent, Traceable Sample Card Processing. The easyPunch STARlet provides everything needed for hands-free sample card punching and extraction, along with sample traceability.

The AD6020 combines BioDot’s precision low volume dispensing technologies and a large customizable nest to create a high throughput, multi-channel automated liquid handling workstation. Nests for MTPs and slides are available or the system can be customized for unique spotting surfaces and/or labware. Manufacturing throughput can be optimized through single/dual shuttle nest designs.

Features:Cost Efficient - Friction-fed mini rollers eliminate unnecessary waste of the master stripUser FriendlySimple handheld operationSafety interlock deviceEasy blade cleaningFlexibleAdjustable material guidesVarious blade speedsProduct OptionsLeading Edge SensorTarget Sensor (requires Leading Edge Sensor)Anti-StaticCustom OptionsReel FeedBottle Collection

The Automated Laminating system is a modular design to accommodate various numbers and types of materials. Each material is fed from adjustable spindles through guides and under a pressure roller to assure complete adhesion to the plastic support backing. The system provides the ability to individually remove kiss cut adhesive liners for individual laminate materials. For fragile materials like nitrocellulose, alignment is con…

Recombinant Rubella (strain F-Therien) virus-like particles consisting of spike glycoprotein E1, spike glycoprotein E2 and Capsid protein, produced in mammalian HEK293 cells.

Novel Coronavirus 2019-nCoV (SARS-CoV-2) Spike Glycoprotein (S1) is a recombinant antigen which contains the Spike protein amino acids 1-674. Spike S1 protein is manufactured in HEK293 mammalian cells, ensuring the most authentic post-translational modifications.

Novel Coronavirus 2019-nCoV (SARS-CoV-2) Spike Glycoprotein (S2) is a recombinant antigen which contains the Spike S2 protein, amino acids 685-1211. Spike S2 is manufactured in mammalian HEK293 cells to ensure the most authentic post-translational modifications.

The Native Antigen Company offers a selection of complementary easy-to-use antibody conjugation formats, with a wide range of labels suitable for use in most applications. On request we can also undertake custom conjugation of proteins and antibodies.

With decades of experience in the field of native antigen and recombinant protein production, and assay development, The Native Antigen Company is able to undertake a wide range of custom projects on your behalf.