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Products, services, reviews and techniques used in the preliminary investigations of the disease; the cell biology, genetics and protein pathways using tissue culture, cloning and imaging.

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KAPA3G Plant PCR Kits

Kapa Biosystems, Inc.

KAPA3G Plant PCR Kits are designed for PCR of plant-derived DNA, using either purified DNA or DNA prepared by crude extraction methods (crude sample PCR). In addition, the KAPA3G Plant PCR Kit can be used to amplify DNA from plant material added directly to the PCR (direct PCR). The KAPA3G Plant PCR Kit contains KAPA3G DNA Polymerase, a novel, third-generation (3G) enzyme which was engineered via a process of directed evolu…

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KAPA2G Fast PCR Kits

Kapa Biosystems, Inc.

KAPA2G Fast DNA Polymerase is a second-generation (2G) enzyme engineered for higher processivity and speed, offering significantly faster extension rates than wild-type Taq polymerase. In addition to speed, KAPA2G Fast provides higher yields and sensitivity than competitor enzymes across a broad range of targets.   Features: Reduce cycling times up to 75% Extension times as low as 1 sec per kilobase Broad c…

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KAPA Mouse Genotyping Kits

Kapa Biosystems, Inc.

From tail to type in 1 hour! KAPA Mouse Genotyping Kits include KAPA Express Extract, a novel thermostable protease and buffer system that allows for the extraction of PCR-ready DNA from mouse tissue in as little as 15 minutes, and KAPA2G Fast Genotyping Mix with dye, containing a DNA polymerase engineered via directed evolution for high processivity and extreme speed. The combination of KAPA Express Extract and KAPA2G Fast…

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KAPA Long Range PCR Kits

Kapa Biosystems, Inc.

The KAPA Long Range PCR system is a blend of Taq DNA polymerase and an engineered archaeal (B-family) DNA polymerase possessing proofreading capability. This two-enzyme system is designed specifically to support long-range and/or sensitive PCR, and possess 3 – 4X higher fidelity than Taq polymerase. In the hot-start formulation, KAPA Long Range is combined with a proprietary antibody that inactivates the enzyme until the fi…

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KAPA Blood PCR Kits

Kapa Biosystems, Inc.

KAPA Blood DNA Polymerase is a second-generation enzyme derived through a process of directed evolution, and is the first DNA polymerase engineered specifically for the amplification of DNA directly from whole blood. DNA fragments may be amplified directly from reactions containing 1%-20% (v/v) whole human blood without pretreatment of blood samples or DNA isolation, significantly reducing contamination risk, turnaround tim…

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KAPA Taq PCR Kits

Kapa Biosystems, Inc.

KAPA Taq DNA Polymerase is based on the single-subunit, wild-type Taq DNA polymerase of the thermophilic bacterium Thermus aquaticus. KAPA Taq and KAPA Taq HotStart DNA Polymerase have 5′-3′ polymerase and 5′-3′ exonuclease activities, but no 3′ to 5′ exonuclease (proofreading) activity. The enzyme has an error rate of approximately 1 error per 2.2 x 105 nucleotides incorporated. In the hot start formulation, the KAPA Taq i…

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KAPA dNTPs

Kapa Biosystems, Inc.

High-quality, molecular-grade dNTPs. Kapa offers premium grade dNTPs for PCR. KAPA dNTP Mix contains dATP, dCTP, dGTP, and dTTP supplied at a concentration of 10 mM each.   Applications: Standard PCR qPCR cDNA synthesis DNA sequencing DNA labeling Microarrays

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LOBSTR E. coli Expression Strain for One-step Purification

Kerafast

Ideal for low-expressing protein targets, the LOBSTR E. coli expression strain allows for one-step polyhistidine-tag affinity purification by eliminating the two major E. coli contaminants. Traditionally, a major drawback to using polyhistidine-tag affinity purification for proteins expressed in E. coli is contamination resulting from the presence of two naturally histidine-rich proteins in E. coli, ArnA and SlyD. LOBSTR (l…

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IRT-7000 FT-IR Microscope

JASCO (USA)

JASCO also offers the IRT-7000, an innovative FT-IR multi-channel microscope accessory with advanced functionality which drastically improves the ability to obtain microspectroscopic data.The IRT-7000 offers two detectors as standard; a 16-channel linear array detector for infrared sample imaging and a single-point MCT detector. The combination of the standard automatic sample stage and "IQ Mapping" function allows mapping ana…

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LC-4000 Series PDA Detectors

JASCO (USA)

The LC-4000 Series includes three PDA detectors.The MD - 4 017 is a useful replacement for a single wavelength detector, the MD-4015 is the workhor se for UV- visible detection in the range 200 to 600nm and the MD-4010 is designed for high sensitivity and high spectral and time resolution. The MD-4010 PDA detector offers the highest detection sensitivity, equivalent to a single wavelength detec tor. Making use of a 1024 eleme…

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LC-4000 Circular Dichroism Detector

JASCO (USA)

The CD-4095 is a unique HPLC detector for measuring circular dichroism developed from the market leading J-Series circular dichroism spectropolarimeter.Optically active compounds with a chromophore close to a chiral center may absorb circularly polarized light, which can be detected with excellent sensitivity and selectivity. When chiral compounds are measured using a UV-Visible detector, the d- and l- enantiomers cannot be di…

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V-730 UV-Vis Spectrophotometer

JASCO (USA)

User friendly features include the IQ Accessory function for automatic accessory recognition and IQ Start for immediate start of registered data collection applications when conducting routine measurements.Two graphical user interfaces are available including a newly redesigned intelligent remote module (iRM) with a color LCD touch screen or Spectra Manager II software, the latest version of JASCO's innovative, cross-platform…

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V-760 UV-Vis Spectrophotometer

JASCO (USA)

The optical bench in the V-760 UV-visible spectrophotometer utilizes a double monochromator to provide exceptional resolution with extremely low stray light (0.00008%) to assure more precise measurement over the widest photometric range.The V-760 provides excellent sensitivity for diffuse reflectance or transmittance of solid and liquid samples using an integrating sphere. The spectral bandwidth can be set as narrow as 0.1 nm…

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V-750 UV-Vis Spectrophotometer

JASCO (USA)

The optical design employs ‘true double beam optics’ with a chopper providing timed sample, reference and dark current measurements.A high sensitivity PMT (photomultiplier tube) provides accurate and reproducible measurements of both low (and high) concentration samples. By controlling the high voltage applied to the PMT, the dynode feedback circuit allows a wider dynamic range. It also provides excellent sensitivity for diffu…

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V-770 UV-Visible/NIR Spectrophotometer

JASCO (USA)

The V-770 UV-Visible-Near Infrared (UV-Vis/NIR) spectrophotometer features a monochromator with automatically exchanged dual gratings: 1200 lines/mm for the UV/VIS region; 300 lines/mm for the NIR region. A PMT detector is provided for the UV-visible region and a Peltier-cooled PbS detector is employed for the NIR region. Both gratings and detectors are automatically exchanged within the user selectable 800 to 900 nm range.

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V-780 UV-Visible/NIR Spectrophotometer

JASCO (USA)

The V-780 UV-Visible-Near Infrared (UV-Vis/NIR) spectrophotometer features a monochromator with automatically exchanged dual gratings: 1200 lines/mm for the UV/VIS region; 600 lines/mm for the NIR region. A PMT detector is provided for the UV-visible region and a high sensitivity InGaAs photodiode detector is employed for the NIR region. Both gratings and detectors are automatically exchanged within the user selectable 800 to…

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Epigenetics-grade antibodies for ChIP and ChIP-seq

Diagenode

ChIP, ChIP-seq, and methyl antibodies for stem cell studies. In recent years, studies suggest that the mammalian genome undergoes various epigenetic modifications during development and embryonic stem cell (ESC) differentiation. Understanding the mechanisms that control these epigenetic signals is essential in deciphering stem cell biology and the patterns of gene expression during cellular differentiation. ESC gene express…

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