Drug discovery > Lead Discovery Products & Reviews

This liquid handler offers a two-rack platform for large or small volume injection and automatic fraction collection using tubes, vials, or microplates. Its small footprint makes it an ideal choice for labs where bench space is limited.

This small footprint, medium capacity liquid handler and autosampler offers small-to-large volume injection, fraction collection, and liquid handling capabilities. Its dynamic syringeless pumping system is capable of delivering microliters to hundreds of milliliters, with no change in hardware.

This liquid handler provides a versatile, large capacity platform that can be configured for injection, fraction collection, and re-injection as part of a semi-preparative or preparative HPLC purification system. With optional accessories, it can also be used as a flexible liquid handler for performing a wide variety of automated, unattended liquid handling applications.

This VERITY® oligonucleotide purification system offers a single, automated HPLC system for the purification, analysis, and desalting of reagent-grade synthetic oligonucleotides in one continuous run. The system seamlessly changes between preparative and analytical scales, saving time and equipment space, while built-in error handling allows for unattended operation.

Cellpuri® is a disposable chip that enriches cells without the use of centrifugation method. Cells are being separated using the rheological phenomenon inside the microchannels where the cell suspension pass through to filter out waste medium and collect the enriched cells in the outlet.

The XcytoMatic® 40 (XM40™) is a high-throughput cell density and viability analyzer that can run 24 samples in under 14 minutes. The variation between cell counts for these samples is under 3%. If scale-out and scale-up is a concern, you can trust each XM40™ instrument in your production to deliver the same quality results.

Disruptive technology for the characterization of small molecules and fragments. With enhanced sensitivity, expanded thermal options, and advanced microfluidics, the Carterra Ultra™ platform is our most sensitive instrument for interrogating multiple proteins and off-target binding in parallel.

Disruptive Technology for Screening and Characterization. Enhanced sensitivity and fast data collection rate build upon unmatched capabilities in throughput and enable assays such as TPDs/PROTAC®s, kinase, cytokines, DELs, and protein:protein inhibitors.

The AptaFluor® SAH Methyltransferase Assay Kit enables ultra-sensitive, direct detection of SAH—the universal product of methyltransferase reactions—using a riboswitch-based TR-FRET format. With no coupling enzymes required, it delivers high signal-to-background, Z’ ≥ 0.7, and is fully HTS-compatible for drug discovery and inhibitor screening.

BellBrook Labs’ Lead Discovery Services deliver expert support for hit-to-lead efforts. From inhibitor screening and potency profiling to residence-time, mechanism-of-action, and selectivity studies, their team tailors efficient enzymatic assays to your program—accelerating lead advancement with precision and flexibility.

The Transcreener® cGAMP cGAS Assay Kit offers mix-and-read fluorescent detection of cGAMP—the product of cGAS activity—with no coupling enzymes required. Available in FP or TR‑FRET readouts (far-red tracers minimize interference), it’s HTS-ready (Z’ ≥ 0.7), automation-compatible, and validated on 96‑, 384‑, and 1536‑well formats for enzyme kinetics, SAR, and inhibitor screening.

The CD73 activity assay for HTS and hit-to-lead. Measure specific activity of CD73 in a simple mix-and-read format. The kit is designed for compound library screening and follow-up inhibitor discovery.

The Transcreener dAMP Exonuclease Assay directly measures dAMP produced by exonuclease enzymes as they cleave polynucleotides. 

Simplify your workflow and save valuable laboratory time with the fully automated MACS® Sampler, a perfect extension for the MACS® Matchmaker instrument, allowing you to fully integrate automatization solution for your interaction studies.

With the MACS® Matchmaker you can experience a robust platform that delivers quantitative data on binder affinity, kinetics, and specificity in complex samples. Unlock new possibilities in your research today – because every target deserves its perfect match!

PurePlus™ Deep Well Plates 96-well plates are designed for automation, high throughput screening (HTS), or heavy lab use. Each well holds either 1.2 mL or 2.2 mL and has smooth inside surfaces to ensure that all of your samples can be pipetted.

PCR Strip Capping Tool

Countable PCR is the only PCR-based method that directly counts your targets, giving you unprecedented and highly sensitive insights into your samples. Don't be limited by qPCR, dPCR, or even NGS. Find even the rarest targets when you experience single-molecule precision and ultra-high sensitivity in a familiar PCR workflow. Plus – quickly develop a new multiplex assay in 3 days.

In-depth understanding of complete genome in human, aninal, plant and microbe with end-to-end services.  

Sequencing only service for customer-premade libraries at different read lengths and capacities to suit any cost, project scale and turnaround with the world-leading, powerful, and sophisticated sequencing platforms (Illumina, Pacbio, and Oxford Nanopore). 

16S/18S/ITS rRNA amplicon metagenomic sequencing employs universal primers to target specific regions to identify the phylogeny and taxonomy from complex microbiomes.

Single cell RNA sequencing uncovers the complexity of cellular diversity to employ the study of unusual cell types, cell-lineage associations, and samples of heterogeneous nature with 10x Genomics technology.

Long Read Sequencing (LRS) service employs cutting-edge technologies such as Oxford Nanopore and PacBio platforms for decoding complex genomes, completing transcriptomes, exploring metagenomes, and investigating structural variations with unmatched precision.  

Whole exome sequencing allows for sequencing human and mouse exomes in an array of panel options, which facilitates research contexts and clinical contexts.

Flare™ is a ligand-based and structure-based drug design platform. Through high-resolution 3D visualization and in-depth analysis of target structures and potential ligands, Flare enables users to optimize and prioritize new molecules efficiently and effectively.