Drug discovery > Lead Discovery Products & Reviews

Optimize your workflow with the Agilent GlykoPrep (formerly ProZyme) N-glycan sample preparation platform.

The Agilent GlykoPrep (formerly ProZyme) platform streamlines N-glycan sample preparation.

Remove contaminants from glycan samples with simple protocols

Choose from a variety of tools with Agilent AdvanceBio Sialic Acid kits (formerly ProZyme) for sialic acid profiling and quantitation applications

The Agilent AdvanceBio Gly-X (formerly ProZyme) technology is a new generation of N-glycan sample preparation

Introducing RNAscope HiPlex assay to expand your in situ hybridization potential.

The FROG-5000™ can detect volatile organic compounds (VOCs) in  air ,  water , and  soil , delivering lab-quality results in less than 10 minutes. It is the only portable gas chromatograph that weighs less than 5lbs (2.2kgs).

A revolution in GPC Cleanup system design, the AccuPrep MPSTM combines flexibility and cutting-edge features in a smaller package.

The Affinity Removal LC Column - Human Albumin is designed to chromatographically remove the most interfering high-abundance protein (albumin) from human samples (e.g., plasma, serum, urine, or cerebrospinal fluid). They are compatible with most FPLC or HPLC pumps or instruments, including Agilent 1200/1100 instruments.

Agilent AdvanceBio SEC columns ensure easy, fast, and accurate quantitation for mAb aggregation and fragment analysis. AdvanceBio SEC offers two different particle sizes, 2.7 and 1.9 µm.

Agilent Bio SEC-3 HPLC columns are a breakthrough technology for size exclusion chromatography (SEC). They are packed with spherical, narrowly dispersed 3 µm silica particles coated with a proprietary hydrophilic layer.

Agilent Bio SEC-5 HPLC columns are packed with 5 µm silica particles coated with a proprietary, neutral, hydrophilic layer for maximum efficiency and stability. Our specially designed packing also promotes high pore volume, improving both peak capacity and resolution. 

Method validation is a critical step for biotherapeutic drug development. It ensures that the analytical method is suitable for its intended purpose, and that it meets regulatory requirements.

Agilent ZORBAX GF-250 and GF-450 size exclusion (gel filtration) columns are for size separations of proteins and other biomolecules. The separation range is 4,000-900,000 for globular proteins when using GF-250 and GF-450 columns in series.

Agilent AdvanceBio MS Spent Media columns are HILIC columns that deliver fast, sensitive, and reproducible separations of underivatized amino acids and other polar metabolites found in bioprocessor cell culture media for mass spectrometric detection.

Agilent Bio Ion-Exchange HPLC columns are packed with polymeric, nonporous, ion-exchange particles. Bio Ion-Exchange Columns are designed for high resolution, high recovery and highly efficient separations of peptides, oligonucleotides and proteins.

Thorough characterization of monoclonal antibodies includes the identification and monitoring of acidic and basic isoforms. The Agilent Bio MAb HPLC columns feature a unique resin specifically designed for high-resolution charge-based separations of monoclonal antibodies.

PL-SAX for Biomolecules is ideal for the anion-exchange HPLC separations of proteins and deprotected synthetic oligonucleotides under denaturing conditions.

PL-SCX is a macroporous PS/DVB matrix with a very hydrophilic coating and strong cation-exchange functionality. 

ZORBAX Ion Exchange columns are available as both Strong Anion-Exchange (SAX) and Strong Cation-Exchange (300SCX) columns. 

Agilent 2-AA (formerly ProZyme) labeled N-glycan standards and libraries are commonly used as qualitative standards for LC/FLD and LC/MS. 

Agilent 2-AB (formerly ProZyme) labeled N-glycan standards and libraries are commonly used as qualitative standards for LC/FLD and LC/MS. 

Agilent 2-AB (formerly ProZyme) labeled O-glycan standards are commonly used as qualitative standards for LC/FLD and LC/MS.

Agilent APTS (formerly ProZyme) labeled glycan standards are commonly used for qualitative N-glycan identification or as migration standards for capillary electrophoresis with laser-induced fluorescence (CE/LIF).

Agilent Blood Group Oligosaccharides (formerly ProZyme) standards are offered as disaccharide and trisaccharide forms.