Drug discovery > Lead Discovery Products & Reviews
Identification and optimization of the chemical, series of chemicals or bio-molecule that will interact with the target using impartial, expert opinion about the best equipment, services and the latest techniques
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Rotary Cone Sample Divider LABORETTE 27
Fritsch GmbH - Milling and SizingThe most precise way of sample division
Corning® 96-well Clear Flat Bottom Polypropylene Not Treated Microplate, 25 per Bag, without Lids, Nonsterile
Corning Life SciencesFeature uniform skirt heights for greater robotic gripping surface Solvent resistant polypropylene provides compatibility with many common organic solvents (e.g., DMSO, ethanol, methanol) DNase- and RNase-free Total volume is 360 µL; recommended working well volume is 75 to 200 µL Without lids; lids, sealing mats and tapes supplied separately
CBC’s Next-Gen Sequencing Services
febit holding GmbHThe introduction of NGS technologies into the market has changed the way we think about scientific approaches in basic, translational and clinical research. The development of NGS applications is a rapidly evolving field – making for exciting times in genomic studies. The ability to produce large numbers of readouts at low cost makes NGS platforms useful for many applications. Next-generation sequencing applications include:•…
AVANCE 1000
Bruker BioSpin launches a breakthrough one Gigahertz Ultra-High Field AVANCE 1000 MHz NMR spectrometer. Incorporating a record-breaking 23.5 Tesla standard-bore (54 mm) superconducting NMR magnet, the AVANCE 1000 MHz NMR spectrometer, brings one Gigahertz technology to NMR research. AVANCE 1000 MHz NMR Spectrometer with the first 1 GHz CryoProbe installedThe high field strength and high field stability in combination with the…
Control your Cells with CYTOOplates™
CYTOO Inc.CYTOOplates are optical grade, glass-bottom microplates in 96 or 384-well format with black-side upper structures for fluorescence applications offering reduced background and minimum scattered light. Each well holds an array of over 4,000 (96-well) or 1,000 (384-well) identical micropatterns. CYTOOplates are compatible with your High Content Screening equipment.
CYTOOchamber™
CYTOO Inc.The CYTOOchamber™ is a 35mm footprint device specially designed and manufactured for the 2x2cm² square CYTOOchip™ format which enables you to do high resolution timelapse microscopy. The CYTOOchamber uses a patented magnetic system for easy assembly. The CYTOOchamber has the same footprint as standard 35mm culture dishes and therefore will fit into all 35mm microscope stage adaptors. Components: • 1 bottom plate • 1 upper mai…
FMB210 - Fully automatic monobloc
Watson-Marlow Inc.SCOPE OF APPLICATION ASEPTIC FILLING • Pharmaceutical • Diagnostic • Biopharmaceutical • Disposable filling • Aseptic liquid filling • Peristaltic liquid filling • No cleaning validation • Easy product change-over • Ideal for small batch production • No cross contamination • High accuracy filling VERY COMPACT Machine dimensions are 1.13 x 2.05 m, i.e. FMB210 takes up very little space in a cleanroom. SHORT CHANGE OVER TIME Ide…
MS-3 Compact Laser Barcode Scanner
Microscan Systems, Inc.The MS-3 laser scanner offers the fastest read performance in embedded compact bar code scanners. The wide scan angle of 70 degrees is coupled with ultra-compact size and flexible mounting. • Decodes/second: up to 1000 • Read Range: 2 to 10” (51 to 254 mm) • Wide Scan Angle • IP54 Enclosure High performance and flexibility make the MS-3 the optimal choice for reliable reading in embedded instruments. Compact & Lightweight: The…
NorDiag Bullet
LTF Labortechnik GmbH & Co. KGThe NorDiag Bullet instrument is CE IVD ready and provides TRUE walk away automated sample preparation for molecular diagnostics. The NorDiag Bullet is compact yet flexible, designed to provied targetend solutions for the user's needs.
USP 4 / Apparatus 4
SOTAX AGUSP Apparatus 4 Product Details:• Cells designed for MR, CR and ER tablets, capsules, suppositories, powders, pellets, APIs, implants, medical devices, ophtalmic devices, drug eluting stents, creams, gels, suspensions, microspheres, liposomes and nanospheres • Suitable for R&D and QC, manual and automated sampling, firmware or software driven, linked to UV, UVFO (UV Fiber Optic) and fraction collector for HPLC • Evolution of t…
Optical Power and Energy Meters
Newport Corp.• One of the most advanced power meters in the market • Using state-of-the-art analog board for superb sensitivity, accuracy, and speed • Power measurement capable of 11 fW – 20 kW • Energy measurement capable of 7 µJ – 20 kJ • Measurement rep-rates up to 10 kHz • Sampling rate up to 250 kHz
Thermo Scientific Accela 1250 Pump
Thermo Fisher ScientificUHPLC quaternary solvent delivery system with operating pressure to 1250 barThe Thermo Scientific Accela high-speed chromatographic system provides fast, efficient HPLC and U-HPLC in One Efficient, Limitless System. The Accela™ 1250 High Speed LC pump provides accurate and precise flow and gradients under all operating conditions with minimum pulsation. Features of the UHPLC Accela 1250 pump: • Quaternary capabilities with f…
Evolution Array UV-Visible Spectrophotometer
Thermo Fisher ScientificFull Spectrum Data Acquisition Fast data acquisition and superb reliability make the Thermo Scientific Evolution Array spectrophotometer the cornerstone of your complete analytical environment. Instant full-spectrum analysis, room light immunity, and a complete line of accessories deliver simplicity and capability that is second to none. Photodiode array technology allows you to acquire full-spectrum UV-Visible data almost i…
Universal Caps
Heathrow ScientificUniversal Caps - Seal multiple size tubes with one size cap. Easy to use, polyethylene caps feature a universal fit. Seal caps with one handed use. Caps provide tight, leak-proof seal for standard glass or plastic tubes. The innovative design of the Heathrow Scientific Universal Caps fit larger tube sizes inverted and smaller tube sizes upright. Compatible with tube sizes 10 mm, 12/13 mm or 16 mm. Available in Blue, Green, Red…
Action Potential Duration (APD) Testing on hESC-Derived Cardiomyocytes
ChanTest CorporationEvaluate compounds in human stem cell-derived, ventricular-type cardiomyocytes. Effects on action potential parameters are evaluated in single human cardiomyocytes using patch-clamp recording Benefits: Human ion channels expressed in a native cardiac environment Detects AP Prolongation (QT risk) and EADs (Torsade trigger) Stable recordings at physiological temperature with minimal diffusion delays Cost-effective Ra…
InviGenius
STRATEC Molecular GmbHThe InviGenius provides advanced and reliable performance in automated nucleic acid sample preparation in combination with the well established magnetic bead based InviMag technology for DNA and RNA purification – especially for increased standardization and streamlined laboratory workflows. Innovative functions and optimized protocols enable reliable results of high quality. The InviGenius automated system, with built-in touc…
VLife QSARpro
VLife Sciences Technologies Pvt. Ltd.QSARpro software is designed for identifying the relationship activity with structural parameters and its analysis. What QSARpro offers:• It evaluates more than 1000 molecular descriptors* • It offers not only 2D QSAR, 3D QSAR and GQSAR but also comes with all advanced molecular operations from the VLife Engine • For medicinal chemist, QSARpro offers seamless integration to AutoQSAR*This includes: physicochemical, topological…
MicroSAM
Siemens AGMicroSAM - The new Dimension in Process Gas Chromatography MicroSAM , the newest on-line Process Gas Chromatograph from Siemens, brings a new dimension to the industry - small! Using modern silicon micro-machining techniques achieves miniature size while simultaneously increasing power and versatility. The explosion-proof enclosure contains everything you need for separation and detection of the measured sample integrated into…
Thermo Scientific™ Dionex™ AutoTrace™ 280 Solid-Phase Extraction Instrument
Thermo Fisher ScientificThe Thermo Scientific™ Dionex™ AutoTrace™ 280 Solid-Phase Extraction (SPE) instrument is a powerful, high-throughput workstation dedicated specifically for automating SPE. The Dionex AutoTrace 280 instrument automates the cartridge or disk conditioning, sample loading, rinsing, and eluting steps for large volume aqueous solution extractions (20 mL to 20 L).The unit can process up to six samples in parallel, automatically condi…
Fragment Library
ChemBridge CorporationChemBridge Fragment Library compounds for fragment-based drug discovery and screening.
HENDRIX SM100 system
Microsonic Systems Inc.HENDRIX SM100 - Programmable Ultrasonic Microplate Fluid ProcessorFeatures of the HENDRIX SM100 system: • Processes 24, 96, 384, 1536 and 3456-well polypropylene, polystyrene, and COC SBS format microplates • Compact, modular design - efficient for integration/stand-alone use - Fluid processor unit occupies about ½ sq. ft. of deck space (W: 8.25" D: 8.75" H: 4.25") - Base control unit easily sits underneath lab bench…
GPCR Cell Lines
CCS Cell Culture Service GmbHGPCR Cell Lines - Validated Cell Lines for High-Throughput-Screening In cooperation with Cisbio Bioassays CCS has developed a set of recombinant cell lines stably expressing G-Protein coupled recptors (GPCRs) of high pharmacological relevance. The cell lines have been generated by stable transfection of CHO-K1 cells and subsequent clonal selection. They have been specifically validated for a read-out in homogenous time-resolv…
Membrane Preparation
CCS Cell Culture Service GmbHCell Membranes - Custom Preparation of Cell Membranes from CCS Cell Culture Service Preparations membranes from cell which are expressing a target receptor, transporter or ion channel at a high density are a useful tool in drug research. Embedded in a membrane fragment or vesicle the proteins remain in a functional native confirmation. Ligand binding assay and functional GTP-gammaS assays can be performed with these preparati…
LTQ FT Ultra
Thermo Fisher ScientificThermo Scientific* LTQ FT Ultra combines the most advanced Ion Trap and Fourier Transform Ion Cyclotron Resonance technologies into a single instrument with unprecedented analytical power and versatility. Ultra-high resolution and sensitivity coupled with sub ppm mass accuracy, and MSn are universally available for the toughest applications demanding rigorous structural characterization.