Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Digitonin

Promega Corp.

Digitonin can be used in cell viability and cytotoxicity assays. It is a detergent solution useful for permeabilizing cells and for creating a cytotoxicity chemistry positive control. Supplied at 20mg/ml in DMSO

5.0/5.0
|1 Review



CFSE Cell Division Tracker Kit

BioLegend

CFSE Cell Division Tracker Kit is composed of 5 vials, 100 µg per vial of CFSE (formally known as 5-(and 6)-Carboxyfluorescein diacetate succinimidyl ester of CFDA SE), and 500 µl of anhydrous DMSO. CFSE is able to passively diffuse into cells. Inside the cell, its acetate groups are cleaved by intracellular esterases, and the molecules are converted to fluorescent esters. CFSE is retained within the cell and covalently couple…

4.5/5.0
|2 Reviews



Toluene-d8

Restek Corp.

Certified reference materials (CRMs) manufactured and QC tested in ISO-accredited labs satisfy your ISO requirements. 

5.0/5.0
|1 Review


The PhysioMimix™ OOC Range of Single and Multi-organ Microphysiological Systems (MPS) by CN Bio

CN Bio

PhysioMimix™ microphysiological systems generate in vitro microtissues that mimic the structure and function of human tissues and organs. Through the simulation of human biological conditions, they bridge the gap between traditional cell culture and human studies, reliably predicting drug effects to facilitate the accelerated development of safe and efficacious therapeutics. 

4.9/5.0
|3 Reviews

Elevated Plus Maze

Kinder Scientific

Kinder Scientific’s Elevated Plus Maze has higher resolution and specially created measures that enhance your ability to quantify anxiety. For example, with beams mounted on the edge of the open arms, we capture the animal hanging its head over the edge. Going out on the cliff is one thing, hanging over the edge of it is another! And the Elevated Plus Maze’s high resolution can separate arms into multiple zones. These multiple…

4.7/5.0
|1 Review

Hana Single Cell Dispenser

Bio-Techne

The Namocell Hana Single Cell Dispenser makes single cell isolation and sorting effortless with 1 laser and 2 fluorescent channels. Hana offers 3 sorting modes for versatile cell isolation: Single Cell Dispensing, Rare Cell Enrichment and Bulk Cell Sorting. This benchtop instrument uses microfluidics technology that combines flow cytometry and liquid dispensing to sort and dispense single cells directly into 96-well or 384-we…

4.8/5.0
|12 Reviews

PatentSafe

Amphora

The most popular replacement for the bound lab notebook PatentSafe is Amphora’s direct replacement for the bound paper notebook. As you might expect from the name, one of its key drivers is to create evidence which can be used in the defense of patents. PatentSafe is a flexible, cost effective solution which can be used standalone or in conjunction with one or more ELNs from Amphora or other suppliers. At Amphora we beli…

4.7/5.0
|1 Review


Model 2500 Water Bath Dissolution Instrument

Distek, Inc.

The Distek Model 2500 Dissolution System offers great flexibility and configurability. It can be configured as USP Apparatus 1, 2, 5, and 6 plus intrinsic dissolution. The extensive users, method, and reporting storage capabilities are enabled by a brilliant touch screen.   

5.0/5.0
|1 Review

LIVE/DEAD™ Sperm Viability Kit

Thermo Fisher Scientific

The LIVE/DEAD Sperm Viability Kit provides a novel fluorescence-based assay for analyzing the viability and fertilizing potential of sperm by fluorescence microscopy or flow cytometry. Membrane-permeant SYBR® 14 nucleic acid stain labels live sperm with green fluorescence, and membrane-impermeant propidium iodide labels the nucleic acids of membrane-compromised sperm with red fluorescence.

5.0/5.0
|1 Review

Heidelberg Retina Tomograph

Heidelberg Engineering Ltd.

The Heidelberg Retina Tomograph (HRT) is based on fast and reproducable topographic measurements. The glaucoma module premium edition provides high-resolution two- and three-dimensional images of the optic nerve head, the retina module of the retina and the rostock cornea module of the cornea.  Rostock Cornea Module With the Rostock Cornea Module (RCM) the HRT becomes a high-resolution confocal cornea microscope to recei…

5.0/5.0
|1 Review




CELL HANDLERTM, Cell picking and imaging system

Yamaha Motor Co.

The CELL HANDLER is an automated, damageless system for isolating a single cell or a single organoid/spheroid through imaging, picking and transfer of the cells individually to microtiter plates or PCR tubes, 3D-cells grown in hydrogel medium can also be isolated. This morphological/phenotypic image-based isolation system is applicable for various uses, e.g. cell-based assays, omics studies and cell line development.

4.8/5.0
|5 Reviews



CERTUS FLEX

Fritz Gyger AG

The CERTUS FLEX is one of the most flexible solutions to precisely dispense a wide range of liquids, reagents and cells at high speed saving valuable time and costs.

4.8/5.0
|6 Reviews


NovaFluor Conjugation Kit

Phitonex

The NovaFluor Conjugation Kit provides a simple workflow to conjugate each of our 3 NovaBlue and 3 NovaYellow labels to your antibodies with just 3 pipetting steps.

5.0/5.0
|2 Reviews