Drug discovery > Pre-Clinical Development Products & Reviews

The PathDetect Signal Transduction Pathway cis-Reporting Systems are designed for simple, rapid, and convenient assessment of the in vivo activation of signal transduction pathways. There are a series of inducible reporter plasmids that contain the luciferase reporter gene driven by a basic promoter element (TATA box) plus a defined inducible cis-enhancer element.  Identify pathway-specific transcription activation  Easier,…

The Mitochondrial membrane potential detection kit uses a unique fluorescent cationic dye, JC-1, to signal the loss of mitochondrial membrane potential. In healthy non-apoptotic cells, the dye stains the mitochondria bright red.  Detect the loss in mitochondrial membrane potential - Early indicator of cellular apoptosis  Convenient kit format  Use with flow cytometer, fluorescence plate reader, fluorescence microscope

Agilent's GeneSpring provides powerful, accessible statistical tools for intuitive data analysis and visualization. 

SureCall is a research desktop application combining both novel and widely accepted opensource algorithms for end-to-end NGS data analysis from alignment to categorization and annotation of mutations, supporting Agilent Target Enrichment applications. 

The In Situ beta-Galactosidase Staining Kit provides an easy and rapid method to determine transfection efficiency by indicating beta-Galactosidase activity in individual intact cells.  In situ staining of cells directly in dishes without removing or manipulating cells  Rapid detection of Ÿ-gal activity in transfected cells  Results in 24 hours  Maximum signal with low background  Deep blue staining reaction  Kit in…

Agilent's GeneSpring Workgroup provides a robust data management and analysis environment for GeneSpring data and analysis results. It combines a highly scalable architecture, a rich set of analysis tools, and a series of programmatic interfaces that enable multi-campus enterprises to maximize the value of their research.  Store and protect GeneSpring multi-omics data and analysis results  Publish static images  Secure ac…

The MxPro ET qPCR Software component is an optional upgrade for the Mx3005P and Mx3000P qPCR systems. Please note that these instruments have now been replaced by the AriaMx PCR System, and support is available until December 31, 2020.

The 2100 Expert Software for the Agilent 2100 Bioanalyzer provides easy instrument set-up and run control, and offers powerful data evaluation tools for all available assays, automatic and manual integration, smear analysis and many assay-specific tools.     Revision B.02.08 for Windows 7 compatibility    - runs on Windows 7 and Windows XP PC€™s     Supports all current Bioanalyzer assays    - analysis of RNA, DNA, Protein…

The Agilent 280-DS mechanical qualification system (MQS) enables the physical qualification of any dissolution apparatus per enhanced Mechanical Qualification (eMQ) guidelines. Once positioned, the innovative sensing technology allows hands-free measurements to be performed in seconds while measuring and recording critical physical parameters.

Agilent Solutions for Automated NGS Sample Prep provide: Flexibility to automate virtually any NGS reagent Performance to dramatically increase throughput and walk-away time Optimized SureSelectXT protocols to rapidly automate your NGS Sample Prep Agilent NGS Option A and Option B Both Deliver Higher Throughput with Less Hands-On Time Automating your NGS sample preparation with either Agilent NGS Option A or Option B…

Using the same platform as the 708-DS, the 709-DS Dissolution Apparatus ensures productivity, reproducibility and ease of use combined with the convenience of a bath-free design. The 709-DS reduces media heating time with Direct Vessel Heating (DVH) capabilities while insulating the vessel from environmental factors and eliminating water bath cleaning. The exclusive design of the chemically resistant, DVH TruAlign vessel incor…

Build Outstanding Analytical Performance on a Strong Foundation of Sample Prep

Agilent's LC Dissolution Software is an add-on module to the ChemStation Edition of the OpenLAB Chromatography Data Systems. The software controls the analysis of dissolution samples and calculates final dissolution results. In combination with OpenLAB ECM or OpenLAB Data Store, all tools for 21 CFR Part 11 compliance such as access control, data security, data integrity, electronic signatures and archival are provided. Feat…

The 850-DS Dissolution Sampling Station offers the latest capabilities for centralizing laboratory workflow of sample transfer, filtration and collection.

Cartagenia Bench is variant assessment support software for clinical genetics and pathology labs. 

The Agilent Thermal Separation Probe (TSP) provides fast analysis of solid, liquid, and slurry samples. The process is simple, clean, and requires limited or zero sample preparation. Non-vaporized high boiling point ‘dirty sample matrix’– compounds, which can contaminate the GC liner and column, remain inside the micro-vial, and can be discarded after each injection. Use the TSP when testing complex samples in food, forensics,…

Reliable and Intuitive Automated Metabolomics Sample Prep for Increased Throughput, Consistency, and Reproducibility

The NovoCyte Penteon flow cytometer builds on its successful predecessor, the NovoCyte, and provides an expanded set of capabilities that accommodate today’s high-end and increasingly sophisticated multi-color flow cytometry assays. You now have the flexibility to choose from up to 30 fluorescence channels utilizing up to 5 lasers with up to 30 independent detectors. The NovoSampler Q can be integrated into different laborator…

The 708-DS dissolution apparatus is a modular system designed for manual or automated dissolution testing. The instrument can be configured for use with baskets (Apparatus 1), paddles (Apparatus 2), paddle over disk assemblies (Apparatus 5), and rotating cylinders (Apparatus 6), and can accommodate vessel sizes from 100 mL to 2 L.

The Agilent BIO-DIS reciprocating cylinder apparatus (Apparatus 3) is designed to meet current USP Apparatus 3 and EP Reciprocating Cylinder specifications. It is typically used for testing dosage forms in an environment where the the pH/gastrointestinal changes that occur in the body are simulated.

The Agilent reciprocating holder apparatus (USP Apparatus 7) is ideal for automatic dissolution testing of dosage forms requiring a change of media, smaller volume or more vigorous agitation. Typical products tested include extended release tablets, capsules, transdermals, osmotic pumps, and arterial stents.  

The Agilent 400-DS apparatus 7 enables simultaneous, small-volume drug-release testing of up to 13 samples. The 400-DS is designed for testing novel dosage forms such as combination drug products. The innovative design incorporates both the dissolution apparatus and the autosampler.

The NanoDis System provides formulation scientists with accurate release profiles of APIs using conventional dissolution apparatus in an automated, compliant manner. This functionality enables analysts to uncover the best nanoparticle formulation faster and get new drug formulations to market more quickly.  

The intrinsic dissolution apparatus provides the dissolution rate of a pure active pharmaceutical ingredient (API) by exposing the API to a constant surface area of dissolution medium.

The Enhancer (immersion) Cell is a PTFE cell with adjustable volume and a retaining cap to eliminate air pockets trapped against the skin or artificial membrane that provide the diffusion barrier.