Drug discovery > Pre-Clinical Development Products & Reviews

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Products, services, reviews and techniques used in lead molecule delivery, formulation and toxicology, using assays and animal models.

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Image Analysis

Hitachi Software Engineering Europe S.A.

The Image Analysis is a software program for the analysis and digital storage of data from 1-D, 2-D, 96 well, slot/dot blot and DNA sequencing electrophoretic gel images. Image Analysis combines the convenience and economy of a flatbed scanner with the ease and sophistication of Hitachi Software's programming capabilities. Image Analysis will analyze almost any TIFF gel image from a wide range of sources including, fluoresce…

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miVac Duo Concentrator

Genevac

The miVac Duo Concentrator is suitable for use with a wide range of solvents, from volatile organic solvents through to water and some of the higher boiling point solvents. The Duo is a centrifugal vacuum concentrator compatable for use with variety of sample formats including tubes, microplates, vials and round bottom flasks. Making it an ideal "work-horse" concentrator for the busy lab. Combined with a SpeedTrap and JetRo…

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Cellena®

Biomedal

Cellena® is a bioencapsulation portable platform able to encapsulate high molecular weight compounds, microorganisms and cells in homogeneus particles of predictable and controlable size. Designed by Ingeniatrics, it has been specifically developed for biotechnological research. Its performance is based on Flow Focusing® technology. By means of this technology, the elements to be encapsulated are immobilized within a semiperme…

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DX Tracked Specimen Delivery Service

DX

The DX Tracked Specimen Delivery Service CATEGORY B BIOLOGICAL SUBSTANCES Using our Tracked Specimen service, you can send your Category B biological substances through our dedicated pre 9 am delivery network and enjoy the benefits of safe and compliant packaging, bar-code tracking and confirmation that your items are out for delivery. CATEGORY A SPECIMENS – FOR CATEGORY A INFECTIOUS SAMPLES DX does not carry Category A spe…

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Parteck® SLC Excipients

Merck

Created specifically for solid dosage forms, Parteck® excipients are distinguished by outstanding functionalities and a unique particle structure. All Parteck® products are developed under our Functional Particle Engineering concept comprising advanced EMD Millipore technologies for quite extraordinary functionally relevant particle properties. These properties of Parteck® excipients offer decisive advantages to the formulato…

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SuperCool 75 Condenser

Genevac

The demand for a more powerful and colder condenser has naturally arisen as the boundaries of evaporation science are pushed further and further. Users increasingly regard as critical the importance of having the right condenser for the job, with the correct power and temperature profile matched to the characteristics of the evaporator. Genevac has developed the super-powerful and super-cold SuperCool 75, in collaboration wit…

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Solid Phase Extraction Products (SPE cartridges & Well Plates) – SiliaPrep™ & SiliaPrepX™

SiliCycle Inc.

Solid Phase Extraction (SPE) is the basis of analytical laboratories. A crucial step of this process is sample preparation. Therefore we know that a clean sample will yield better results. To achieve this goal SiliCycle has designed SiliaPrep, which is a silica based sorbent exempt of fines, and SiliaPrepX, polymeric based sorbent, that can be found in cartridges, well plates and SPME (Solid Phase Micro-Extraction) cartridges…

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The MiniBlock - SiliCycle

SiliCycle Inc.

The MiniBlock® is an easy-to-use reaction block designed for parallel synthesis and screening. Its unique valve body design enables processes where filtration is critical, including solid-phase organic synthesis, use of scavenger resins with solution phase synthesis and parallel purification via Solid-Phase Extraction (SPE).Make the choice many chemists have made to increase productivity, more so than any other similar tool.…

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Microm™ HM 525 Cryostat

Thermo Fisher Scientific

Achieve superior consistency and reliability of sectioning results with the The Thermo Scientific™ Microm™ HM 525 Cryostat. This semi-electronic cryostat with stepper motor advance allows for fast ,stress-free production of high-quality samples. Ergonomically designed, all settings can be set outside of the cryostat chamber.Microm™ HM 525 Cryostat Features: 7 total freezing stations Peltier with four freezing stations…

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Sample Preparation Devices

HORIBA Scientific

WIN IN EFFICIENCY, AUTOMATION, SPEED & SAFETY WITH OUR NEW SAMPLE PREPARATION DEVICES HORIBA Scientific offers a great range of possible solutions for our analyzers, to save time and ensure that the end results are as accurate as possible! Whatever your analytical solutions: ICP-OES, ICP-MS, AA, Fluorescence X, elemental analyzers, etc.… HORIBA Scientific can provide you with many sample preparation devices, such as: • Grinder…

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EMPROVE® api Portfolio

Merck

Registering an API is complex and thus very time-consuming. That’s why we’ve offer EMPROVE® api: high-quality raw materials for use as active pharmaceutical ingredients. EMPROVE® api raw materials are produced according to cGMP guideline ICH Q7. What’s more, all of our EMPROVE® API production plants are located in Western Europe and follow current environmental standards. And in order to support your products’ compliance with…

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EMPROVE® bio Portfolio

Merck

Raw material qualification is a key factor in assuring the quality and safety of biopharmaceuticals. Even still, performing tests and compiling required documentation on your own is costly and time-consuming. Enter EMPROVE® bio raw materials – your solution for getting products to market faster. EMPROVE® bio raw materials for use in biopharmaceutical production offer specifications adapted for use in upstream or downstream pr…

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EMPROVE® exp Portfolio

Merck

EMPROVE® exp for use as excipient As drug approval procedures grow stricter, regulatory requirements are becoming more demanding for excipients. Our high-quality EMPROVE® exp raw materials for use as excipients not only comply with relevant regulations, but also come with detailed documentation, facilitating lower costs of qualification, so you can get to market faster. EMPROVE® exp dossiers comprise information on the manuf…

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Parteck® Delta M

Merck

Excellent hardness and fast disintegration for wet granulation formulations Mannitol, a sugar alcohol that predominantly occurs in three crystalline forms (alpha, beta and delta polymorph), is especially suitable as an excipient for advanced, highly active APIs thanks to its non-hygroscopicity and low content of reducing sugars. However, standard mannitol (in beta quality) often lacks sufficient binding and compaction propert…

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Parteck® LUB

Merck

With today’s faster, leaner production requirements, the smooth integration of pharmaceutical excipients is essential. And since pharmacopeia now specify functionality in addition to chemical purity, Merck Millipore has adopted these challenges in a new addition to the Parteck® family. Parteck® LUB products are vegetable grades of Magnesium stearate, Calcium stearate and Stearic acid, the most effective excipients for lubrica…

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Parteck® M

Merck

Advanced technology for excellent tabletting properties Mannitol is a sugar alcohol that is especially suitable as an excipient for advanced, highly active APIs due to its non-hygroscopicity and low content of reducing sugars. Merck Millipore's outstanding, directly compressible mannitol Parteck® M is your best choice – especially if your tableting aims at rapid release of high-dose or low-dose actives.Parteck® M belongs to t…

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Parteck® Mg DC

Merck

Parteck® Mg DC – directly compressible without additives The efficient and safe production of tablets – from drugs to fizzy tablets – requires high-quality excipients, especially if higher ingredient concentrations are needed. The best choice for formulation of such drugs are excipients that are directly compressible because they make it possible to produce sufficiently hard tablets at high quality and with fewer process step…

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Parteck® ODT

Merck

Merck Millipore’s Parteck® ODT gives formulators the opportunity to produce top-quality, rapid-acting tablets more cost-effectively than ever. These days, people want no-fuss, no-wait solutions – convenience products that work, quickly and without hassle. This is why many patients prefer orally disintegrating tablets, or ODTs.ODTs allow manufacturers to provide fast-acting medication, add value to existing compounds and – imp…

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Parteck® SI

Merck

Unique functional particles for excellent tabletting properties Parteck® SI, Merck’s outstanding, directly compressible sorbitol, is available in a variety of particle sizes and qualities for virtually any application you can imagine.The unique particle structure of Parteck® SI – loosely packed, needle-like crystals – gives it some quite distinctive physical properties making Parteck® SI the perfect excipient for combining ma…

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Lead Optimization Toxicology Service

Covance Laboratories Inc.

Pursue preliminary appraisal of your drug candidate's safety with Covance's Lead Optimization (LO) Toxicology services. Whether your screening needs are for traditional dosing and observation methods or technologically sophisticated services, Covance LO Toxicology services, Safety Assessment and Abuse Liability provides you with sophisticated preclinical measurements of cardiovascular, endocrine, behavioral or neural function…

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Lead Optimization Pharmacology Service

Covance Laboratories Inc.

Capitalize on the intricacies of research questions honed over thousands and thousands of in vivo pharmacology studies conducted by Covance. Procure Covance's in vivo pharmacology expertise and capabilities for your benefit in the design, validation, conduct, and analysis of animal efficacy pharmacology studies for your drug candidates.Lead Optimization Pharmacology Service Features: Assessing and engaging the target tiss…

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DURAN PURE Premium Cap GL 45

DURAN WHEATON KIMBLE

The Premium Cap is optimally suited for use in the pharmaceutical industry. Two versions are available: packed in Polyethylen bags or STERICLIN®-packed. Without STERICLIN®-packaging the Premium Cap is suitable for dry heat sterilisation up to 260 °C. The sterilisation proof paper is an effective barrier against germs and bacteria, yet it permit the transmission of air, steam, or sterilisation gases.DURAN PURE Premium Cap GL 4…

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DRYPOUR™ Packaging System

Merck

The DRYPOUR™ packaging system for high-quality hygroscopic salts When it comes to products and workflow, you accept nothing but the highest quality in your production – so the same should apply to packaging. Our DRYPOUR™ packaging system is an outstanding new solution for our high-quality hygroscopic salts.This state-of-the-art design packaging system minimizes caking, thus significantly reducing the time needed for material…

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Ready 4 Action Product Planning Service

Ready 4 Action, proprietary feasibility assessment, sets the cornerstone of a cost-effective product development plan. Ready 4 Action is the four-step process used to evaluate the viability of proposed drug products. This important tool enables clients to make the go/no-go decision regarding a given drug's market potential and clinical development feasibility.Armed with the neccessary intelligence, uncover with Ready 4 Action…

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