Drug discovery > Target Discovery Products & Reviews

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Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.

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Echo® 520 Liquid Handler

Beckman Coulter Life Sciences

Imagine preparing assay plates for siRNA screening, compound screening with biochemical and cell-based assays, PCR reactions and more all on a single liquid handling platform, with no tips and no cross-contamination. Labcyte has developed new acoustic droplet ejection (ADE) parameters that deliver built-in intelligence to enable users to transfer many different fluid types from a single instrument. All Echo systems come pre-ca…

4.5/5.0
|2 Reviews

High Capacity RNA-to-cDNA Master Mix

Thermo Fisher Scientific

The High Capacity RNA-to-cDNA Master Mix optimizes cDNA synthesis for high-throughput, real-time gene expression analysis. • Single tube, complete first-strand cDNA synthesis master mix reduces experimental variability and streamlines workflow • 5X concentration provides robust results even with dilute RNA samples and rare or abundant transcripts • Liquid format at –10 and –20°C eliminates freeze/thaw cycles and maximizes chem…

5.0/5.0
|1 Review


Proteome Profiler Antibody Arrays

Bio-Techne

R&D Proteome Profiler Antibody Arrays R&D Proteome Profiler Arrays allow for the measurement of multiple proteins in a single sample. These arrays require no specialized equipment, and eliminate the need for multiple immunoprecipitation/Western blot experiments. R&D Array kits contain buffers, detection antibodies, and membranes spotted in duplicate with capture antibodies carefully selected for their specificity. R&D Arrays…

5.0/5.0
|1 Review

Q-Tof micro

Waters

The Q-Tof micro™ is a high resolution oa-TOF mass spectrometer that provides automated exact mass measurements in an easy-to-use benchtop instrument. It also features a quadrupole mass filter and collision cell for MS/MS analyses, making for a powerful combination that delivers simple exact mass measurement of fragment ions to yield increased confidence in structural elucidation and databank search results. The high-quality da…

4.6/5.0
|3 Reviews

Human VEGF Quantikine ELISA Kit

Bio-Techne

Human VEGF Quantikine ELISA Kit - Human VEGF Immunoassay for the quantitative determination of human vascular endothelial growth factor (VEGF) concentrations in cell culture supernates, serum, and plasma. The R&D Quantikine Human VEGF ELISA is a 4.5 hour solid phase ELISA. This R&D ELISA employs the quantitative sandwich enzyme immunoassay technique. A monoclonal antibody specific for VEGF has been pre-coated onto a microplat…

4.9/5.0
|2 Reviews

Laboratory Mixer

Silverson Machines Inc.

The latest development in high shear lab mixing – the new Silverson L5 Series – is ideal for all laboratory work, research and development, QA analysis and small scale production in all industries. The L5 Series Laboratory Mixer is suitable for the widest range of applications – mixing, emulsifying, homogenising, disintegrating and dissolving – with an efficiency and flexibility unmatched by other machines. With a capacity…

4.9/5.0
|4 Reviews

54-Well HotBlock™

The large capacity SC154 Hot Block will digest up to 54, 50mL samples simultaneously in just a 15 X 21.5" footprint. Constructed of Graphite and Kydex® the corrosion-resistant SC154 was designed for environmental and other acid digestions prior to metals determinations. The SC154 uses a maximum of 1065 watts of power and will maintain sample uniformity to ±1.5°C. Heat is provided by a low-wattage heating mat that provides extr…

4.9/5.0
|2 Reviews


Recombinant Mouse GM-CSF

Bio-Techne

R&D GM-CSF -Recombinant Mouse Protein GM-CSF was initially characterized as a factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GM-CSF is produced by a number of different cell types in response to cytokine or inflammatory stimuli. Specifications and Use for R&D GM-CSF Source of R&D GM-CSF • A DNA…

5.0/5.0
|1 Review

IsoPrime IRMS

Elementar Analysensysteme GmbH

The IsoPrime is a high performance gas source stable isotope ratio mass spectrometer designed to operate in dual inlet or continuous flow modes of operation. The modules are designed to handle samples such as solids, liquids or gases and prepare them to be introduced into the ion source of the IRMS as purified gases. Resultant prepared gases such as (H2, CO2, CO, N2, SO2 or N2O) are then ionised and analysed for their isotopic…

5.0/5.0
|2 Reviews

CellTiter 96® AQueous One Solution Cell Proliferation Assay (MTS)

Promega Corp.

The CellTiter 96® AQueous One Solution Cell Proliferation Assay is a colorimetric method for determining the number of viable cells in proliferation, cytotoxicity or chemosensitivity assays. The CellTiter 96® AQueous One Solution Reagent contains a tetrazolium compound [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; MTS(a)] and an electron coupling reagent (phenazine ethos…

5.0/5.0
|2 Reviews

LifeMatch Fluoroanalyzer

Tepnel Life Sciences PLC

•Amplified DNA can be analyzed with up to 100 different SSO probes simultaneously •Detection of antibodies in serum directed against up to 100 different antigens in a single well with the sensitivity of flow cytometry •Multiplex reactions reduce labor, consumables and assay time •XY platform allows walk-away analysis from 1 to 96 samples at a time •Convenience of automated analysis

4.7/5.0
|1 Review

NimbleGen MS 200 Microarray Scanner

Roche

The NimbleGen MS 200 Microarray Scanner is the first scanner optimized to unleash the full potential and capture the complete picture from NimbleGen DNA microarrays. The MS 200 offers 2 micron resolution and heightened sensitivity to achieve high data quality and confident results from high-density NimbleGen microarrays of today and tomorrow. Critical to the the workflow, NimbleScan and SignalMap software are included to ana…

5.0/5.0
|1 Review

Crimpenstein™ Electric Crimper / Decapper

WHEATON

Electrify your crimping and decapping operations with the new innovative Wheaton Crimpenstein™. The innovative Crimpenstein™ is engineered to improve productivity and efficiency where vials are capped with aluminum seals. The AC powered Crimpenstein™ crimper/decapper provides fast, consistent results with a simple push of a button. The ability to change jaw-sets offers an unmatched level of flexibility and economy for appli…

5.0/5.0
|1 Review

Revolver 360° Sample Mixer

Labnet International

Labnet's Revolver accepts a variety of tube sizes and mixes them horizontally, vertically, or any position in between. Changing the mixing angle is easy, simply turn the rotisserie. No tools are required. Interchangeable rotisseries accept tubes from 1.5 ml to 50 ml. Each rotisserie is split into two halves. Each of the halves can be exchanged to mix more than one tube type at the same time. Each rotisserie half can be rotated…

5.0/5.0
|1 Review


Attune™ Acoustic Focusing Cytometer

Thermo Fisher Scientific

The Attune™ Acoustic Focusing Cytometer gives you both high sensitivity and high throughput. With this technology you can control your sample concentration, the flow rate, the number of photons you detect, the length of your experiment, the number of samples you run, and more. And you can get the most out of your cells with dependable results. What’s more, the Attune™ instrument makes all of this easy to do. Key features:…

4.5/5.0
|3 Reviews

GFP Variant Vectors

Takara Bio

These bacterial expression vectors carry the gene for either GFP (wild type Aequorea victoria green fluorescent protein) or GFPuv (a GFP variant optimized for maximal fluorescence when excited by UV light [360–400 nm]) and are driven by the lac promoter. These vectors can also be used as a source of the indicated fluorescent protein coding sequences. The fluorescent protein gene can be amplified by PCR or readily excised using…

5.0/5.0
|1 Review

Lipofectamine™ RNAiMAX Transfection Reagent

Thermo Fisher Scientific

Lipofectamine™ RNAiMAX Transfection Reagent from Invitrogen   Invitrogen Lipofectamine™ RNAiMAX Transfection Reagent is a proprietary RNAi-specific cationic lipid formulation that offers the highest transfection efficiencies on the widest variety of cell types for siRNA gene knockdown experiments. With Invitrogen Lipofectamine™ RNAiMAX Transfection Reagent you will get: • Superior transfection efficiency requiring…

4.6/5.0
|6 Reviews

pGEM®-T Easy Vector Systems

Promega Corp.

The pGEM®-T Easy Vector Systems are convienent systems to clone PCR products.   They offer all of the advantages of the pGEM®-T Vector Systems with added convieneice of recognition sites for EcoRI and NotI flankin the insertion site. Thus, several options exist to remove the desired insert DNA with a single restriction digestion. The pGEM(R)-T Easy Vectr System II contains JM109 Competent Cells in addition to all pf the…

4.8/5.0
|8 Reviews

Squirt™ Microplate Washer

Matrical, Inc.

The SQUIRT™ multi-format microplate washer is designed for reliability and can be used as a bench top device or in integrated robotic systems. SQUIRT microplate washers can wash any 96, 384, 1536 or 3456 well SBS formatted plate without manifold exchange or adjustments at speeds up to three wash/dry cycles per 15 seconds. The SQUIRT microplate washer's unique slit manifold design minimizes maintenance associated with clogged…

5.0/5.0
|1 Review