Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
R&D Proteome Profiler Antibody Arrays R&D Proteome Profiler Arrays allow for the measurement of multiple proteins in a single sample. These arrays require no specialized equipment, and eliminate the need for multiple immunoprecipitation/Western blot experiments. R&D Array kits contain buffers, detection antibodies, and membranes spotted in duplicate with capture antibodies carefully selected for their specificity. R&D Arrays…
The Q-Tof micro™ is a high resolution oa-TOF mass spectrometer that provides automated exact mass measurements in an easy-to-use benchtop instrument. It also features a quadrupole mass filter and collision cell for MS/MS analyses, making for a powerful combination that delivers simple exact mass measurement of fragment ions to yield increased confidence in structural elucidation and databank search results. The high-quality da…
Human VEGF Quantikine ELISA Kit - Human VEGF Immunoassay for the quantitative determination of human vascular endothelial growth factor (VEGF) concentrations in cell culture supernates, serum, and plasma. The R&D Quantikine Human VEGF ELISA is a 4.5 hour solid phase ELISA. This R&D ELISA employs the quantitative sandwich enzyme immunoassay technique. A monoclonal antibody specific for VEGF has been pre-coated onto a microplat…
The latest development in high shear lab mixing – the new Silverson L5 Series – is ideal for all laboratory work, research and development, QA analysis and small scale production in all industries. The L5 Series Laboratory Mixer is suitable for the widest range of applications – mixing, emulsifying, homogenising, disintegrating and dissolving – with an efficiency and flexibility unmatched by other machines. With a capacity…
The large capacity SC154 Hot Block will digest up to 54, 50mL samples simultaneously in just a 15 X 21.5" footprint. Constructed of Graphite and Kydex® the corrosion-resistant SC154 was designed for environmental and other acid digestions prior to metals determinations. The SC154 uses a maximum of 1065 watts of power and will maintain sample uniformity to ±1.5°C. Heat is provided by a low-wattage heating mat that provides extr…
R&D GM-CSF -Recombinant Mouse Protein GM-CSF was initially characterized as a factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GM-CSF is produced by a number of different cell types in response to cytokine or inflammatory stimuli. Specifications and Use for R&D GM-CSF Source of R&D GM-CSF • A DNA…
The IsoPrime is a high performance gas source stable isotope ratio mass spectrometer designed to operate in dual inlet or continuous flow modes of operation. The modules are designed to handle samples such as solids, liquids or gases and prepare them to be introduced into the ion source of the IRMS as purified gases. Resultant prepared gases such as (H2, CO2, CO, N2, SO2 or N2O) are then ionised and analysed for their isotopic…
The CellTiter 96® AQueous One Solution Cell Proliferation Assay is a colorimetric method for determining the number of viable cells in proliferation, cytotoxicity or chemosensitivity assays. The CellTiter 96® AQueous One Solution Reagent contains a tetrazolium compound [3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt; MTS(a)] and an electron coupling reagent (phenazine ethos…
•Amplified DNA can be analyzed with up to 100 different SSO probes simultaneously •Detection of antibodies in serum directed against up to 100 different antigens in a single well with the sensitivity of flow cytometry •Multiplex reactions reduce labor, consumables and assay time •XY platform allows walk-away analysis from 1 to 96 samples at a time •Convenience of automated analysis
The NimbleGen MS 200 Microarray Scanner is the first scanner optimized to unleash the full potential and capture the complete picture from NimbleGen DNA microarrays. The MS 200 offers 2 micron resolution and heightened sensitivity to achieve high data quality and confident results from high-density NimbleGen microarrays of today and tomorrow. Critical to the the workflow, NimbleScan and SignalMap software are included to ana…
Electrify your crimping and decapping operations with the new innovative Wheaton Crimpenstein™. The innovative Crimpenstein™ is engineered to improve productivity and efficiency where vials are capped with aluminum seals. The AC powered Crimpenstein™ crimper/decapper provides fast, consistent results with a simple push of a button. The ability to change jaw-sets offers an unmatched level of flexibility and economy for appli…
Labnet's Revolver accepts a variety of tube sizes and mixes them horizontally, vertically, or any position in between. Changing the mixing angle is easy, simply turn the rotisserie. No tools are required. Interchangeable rotisseries accept tubes from 1.5 ml to 50 ml. Each rotisserie is split into two halves. Each of the halves can be exchanged to mix more than one tube type at the same time. Each rotisserie half can be rotated…
Designed for processing volumes up to 150 litres • Fluorodyne II membrane is a hydrophilic polyvinylidene fluoride (PVDF) that offers higher flow rates with low protein and preservative binding, with broad chemical and temperature resistance.
The Attune™ Acoustic Focusing Cytometer gives you both high sensitivity and high throughput. With this technology you can control your sample concentration, the flow rate, the number of photons you detect, the length of your experiment, the number of samples you run, and more. And you can get the most out of your cells with dependable results. What’s more, the Attune™ instrument makes all of this easy to do. Key features:…
These bacterial expression vectors carry the gene for either GFP (wild type Aequorea victoria green fluorescent protein) or GFPuv (a GFP variant optimized for maximal fluorescence when excited by UV light [360–400 nm]) and are driven by the lac promoter. These vectors can also be used as a source of the indicated fluorescent protein coding sequences. The fluorescent protein gene can be amplified by PCR or readily excised using…
Lipofectamine™ RNAiMAX Transfection Reagent from Invitrogen Invitrogen Lipofectamine™ RNAiMAX Transfection Reagent is a proprietary RNAi-specific cationic lipid formulation that offers the highest transfection efficiencies on the widest variety of cell types for siRNA gene knockdown experiments. With Invitrogen Lipofectamine™ RNAiMAX Transfection Reagent you will get: • Superior transfection efficiency requiring…
The pGEM®-T Easy Vector Systems are convienent systems to clone PCR products. They offer all of the advantages of the pGEM®-T Vector Systems with added convieneice of recognition sites for EcoRI and NotI flankin the insertion site. Thus, several options exist to remove the desired insert DNA with a single restriction digestion. The pGEM(R)-T Easy Vectr System II contains JM109 Competent Cells in addition to all pf the…
The SQUIRT™ multi-format microplate washer is designed for reliability and can be used as a bench top device or in integrated robotic systems. SQUIRT microplate washers can wash any 96, 384, 1536 or 3456 well SBS formatted plate without manifold exchange or adjustments at speeds up to three wash/dry cycles per 15 seconds. The SQUIRT microplate washer's unique slit manifold design minimizes maintenance associated with clogged…
Laser particle sizing at the push of a button: 10 nm – 2100 µm
The Crystal Phoenix is the ideal protein crystallography dispenser, featuring accuracy, speed and precision to make it the perfect instrument for sitting drop, hanging drop and microbatch reactions. In less than 50 seconds it dispenses protein and screen to the small wells or hanging drop seals. The speed of dispensing the screen and protein eliminates the problem of evaporation even when dispensing as little as 100 nanolite…
The PP-96-M series offers 96 channel high performance pipetting that is ideal for low-volume or high-volume multichannel microplate pipetting and for serial dilution applications. Three models are available: The PP-96H-M for working with higher volumes, the PP-96L-M for low volumes, and the PP-96H-H with extended height for working with deck accessories such as vacuum blocks. The microprocessor-controlled pipetting mechanism…
CryoELITE Cryogenic Vials are the perfect solution for storing, tracking and transporting your irreplaceable samples. 2D Matrix Bar Code Bottom Insert provides a unique identifier for traceability. Unrivaled Cap Seal exceeds DOT and IATA regulations ensuring ultimate protection of samples during transportation and demanding freeze-thaw handling. Loctagon™ Vial Skirt provides stability in the freestanding position; locks…
Cell biology is reliant on the investigation of unmanipulated naturally occurring cells. State-of-the-art receptor specific isolation procedures, however, leave binding reagents on the isolated cells which is likely to induce unwanted cell modifying signalling events. This can now be prevented by using a novel purification approach called Streptamer® technology. Mild purification conditions at low temperatures along with a qui…
