Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
R&D GM-CSF -Recombinant Mouse Protein GM-CSF was initially characterized as a factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is also a growth factor for erythroid, megakaryocyte, and eosinophil progenitors. GM-CSF is produced by a number of different cell types in response to cytokine or inflammatory stimuli. Specifications and Use for R&D GM-CSF Source of R&D GM-CSF • A DNA…
The IsoPrime is a high performance gas source stable isotope ratio mass spectrometer designed to operate in dual inlet or continuous flow modes of operation. The modules are designed to handle samples such as solids, liquids or gases and prepare them to be introduced into the ion source of the IRMS as purified gases. Resultant prepared gases such as (H2, CO2, CO, N2, SO2 or N2O) are then ionised and analysed for their isotopic…
•Amplified DNA can be analyzed with up to 100 different SSO probes simultaneously •Detection of antibodies in serum directed against up to 100 different antigens in a single well with the sensitivity of flow cytometry •Multiplex reactions reduce labor, consumables and assay time •XY platform allows walk-away analysis from 1 to 96 samples at a time •Convenience of automated analysis
The NimbleGen MS 200 Microarray Scanner is the first scanner optimized to unleash the full potential and capture the complete picture from NimbleGen DNA microarrays. The MS 200 offers 2 micron resolution and heightened sensitivity to achieve high data quality and confident results from high-density NimbleGen microarrays of today and tomorrow. Critical to the the workflow, NimbleScan and SignalMap software are included to ana…
Electrify your crimping and decapping operations with the new innovative Wheaton Crimpenstein™. The innovative Crimpenstein™ is engineered to improve productivity and efficiency where vials are capped with aluminum seals. The AC powered Crimpenstein™ crimper/decapper provides fast, consistent results with a simple push of a button. The ability to change jaw-sets offers an unmatched level of flexibility and economy for appli…
Labnet's Revolver accepts a variety of tube sizes and mixes them horizontally, vertically, or any position in between. Changing the mixing angle is easy, simply turn the rotisserie. No tools are required. Interchangeable rotisseries accept tubes from 1.5 ml to 50 ml. Each rotisserie is split into two halves. Each of the halves can be exchanged to mix more than one tube type at the same time. Each rotisserie half can be rotated…
Designed for processing volumes up to 150 litres • Fluorodyne II membrane is a hydrophilic polyvinylidene fluoride (PVDF) that offers higher flow rates with low protein and preservative binding, with broad chemical and temperature resistance.
The Attune™ Acoustic Focusing Cytometer gives you both high sensitivity and high throughput. With this technology you can control your sample concentration, the flow rate, the number of photons you detect, the length of your experiment, the number of samples you run, and more. And you can get the most out of your cells with dependable results. What’s more, the Attune™ instrument makes all of this easy to do. Key features:…
These bacterial expression vectors carry the gene for either GFP (wild type Aequorea victoria green fluorescent protein) or GFPuv (a GFP variant optimized for maximal fluorescence when excited by UV light [360–400 nm]) and are driven by the lac promoter. These vectors can also be used as a source of the indicated fluorescent protein coding sequences. The fluorescent protein gene can be amplified by PCR or readily excised using…
Lipofectamine™ RNAiMAX Transfection Reagent from Invitrogen Invitrogen Lipofectamine™ RNAiMAX Transfection Reagent is a proprietary RNAi-specific cationic lipid formulation that offers the highest transfection efficiencies on the widest variety of cell types for siRNA gene knockdown experiments. With Invitrogen Lipofectamine™ RNAiMAX Transfection Reagent you will get: • Superior transfection efficiency requiring…
The SQUIRT™ multi-format microplate washer is designed for reliability and can be used as a bench top device or in integrated robotic systems. SQUIRT microplate washers can wash any 96, 384, 1536 or 3456 well SBS formatted plate without manifold exchange or adjustments at speeds up to three wash/dry cycles per 15 seconds. The SQUIRT microplate washer's unique slit manifold design minimizes maintenance associated with clogged…
Laser particle sizing at the push of a button: 10 nm – 2100 µm
The Crystal Phoenix is the ideal protein crystallography dispenser, featuring accuracy, speed and precision to make it the perfect instrument for sitting drop, hanging drop and microbatch reactions. In less than 50 seconds it dispenses protein and screen to the small wells or hanging drop seals. The speed of dispensing the screen and protein eliminates the problem of evaporation even when dispensing as little as 100 nanolite…
The PP-96-M series offers 96 channel high performance pipetting that is ideal for low-volume or high-volume multichannel microplate pipetting and for serial dilution applications. Three models are available: The PP-96H-M for working with higher volumes, the PP-96L-M for low volumes, and the PP-96H-H with extended height for working with deck accessories such as vacuum blocks. The microprocessor-controlled pipetting mechanism…
CryoELITE Cryogenic Vials are the perfect solution for storing, tracking and transporting your irreplaceable samples. 2D Matrix Bar Code Bottom Insert provides a unique identifier for traceability. Unrivaled Cap Seal exceeds DOT and IATA regulations ensuring ultimate protection of samples during transportation and demanding freeze-thaw handling. Loctagon™ Vial Skirt provides stability in the freestanding position; locks…
Cell biology is reliant on the investigation of unmanipulated naturally occurring cells. State-of-the-art receptor specific isolation procedures, however, leave binding reagents on the isolated cells which is likely to induce unwanted cell modifying signalling events. This can now be prevented by using a novel purification approach called Streptamer® technology. Mild purification conditions at low temperatures along with a qui…
VLifeMDS (Molecular Design Suite), is a computational chemist’s workbench for computer aided drug design (CADD) and molecule discovery. MDS comes with seamless integration to GQSAR, (Group based QSAR) and SCOPE. VLifeMDS facilitates comprehensive in-silico approach to design. It is able to visualize, predict and analyze small molecules and proteins while studying interactions. VLifeMDS extensively deals with:• Protein structur…
The Oasis LM 600 is a versatile and robust open platform for any liquid handling application, providing state-of-the-art performance in precision and accuracy. The dynamic devices Oasis LM provides superior speed and positional accuracy, down to 0.001 mm repeatability at 2G of acceleration. Combined with the extensive host of available Options and Accessories, the Oasis 600 LM platform is the most compact and powerful bench…
Functional cell-based assays provide more physiologically useful information compared to binding and non-cellular assays. ChanTest offers cell-based assays to over 90 ion channel targets for screening and profiling for both early discovery and safety liability assessment. Both replicating and division-arrested cell lines are available for most targets which have been validated on a variety of automated electrophysiology plat…
Fetal Bovine Serum (FBS) is a sterile, light brown-colored liquid separated from the blood of the bovine fetus. All material meets the approval of the U.S. Department of Agriculture and is obtained from sources free of BSE, Foot and Mouth Disease, and other reportable diseases pertaining to the species. Mediatech offers two types of FBS: U.S.-Sourced: Our U.S.-sourced Premium Fetal Bovine Serum, with the lowest endotoxin and h…
Ficoll-Paque PLUS Ficoll-Paque Plus is a recognized standard in laboratories worldwide for the isolation of human lymphocytes for in vitro studies. Low levels of endotoxin (< 0.12 EU/ml). Maintains viability and representative distribution of B and T lymphocytes. Ready to use sterile medium for isolation of human lymphocytes in high yield from peripheral blood. Ficoll-Paque PLUS is a ready to use, sterile me…
Designed to remove Stripwell™ strips from the egg crate holder
Features include... Rapid vessel exchange with quick-release vessel clamp and hose couplings. Range of single and double jacketed vessels from 100ml to 5 litres. New range of process vessels to mimic larger scale plant or manufacturing reactors. Accepts all leading brands of overhead stirrer and allows easy, tool free adjustment. Triple support stand features heavy duty stainless steel support rods for strength and…
The Model P-97 micropipette puller is the latest generation of the Flaming/Brown type puller for fabrication of micropipettes, patch pipettes and microinjection needles. While retaining many of the features on the Model P-87, the P-97 offers improvements in mechanical, electronic and software design. The result is better control of the pulling process and a higher degree of reproducibility. Features: Environmental chamber…
