Products, services, reviews and techniques used in the identification and validation of the disease-causing target genes and proteins.
Magic Red™ Caspase 3 and 7 Assay is a substrate-based fluorescent apoptosis assay that measures DEVDase enzyme activity in living, intact cells. Detection of caspase 3 and 7 activity (DEVDase enzymes) is a reliable method for assessing apoptotic activity in experimental cell populations. The Magic Red™ caspase 3 and 7 fluorogenic substrate, MR-(DEVD)2, is primarily targeted by caspases 3 and 7 of the apoptotic protease casca…
Research and Clinical Grade RetroNectin Reagent for Retroviral or Lentiviral Transduction. RetroNectin Reagent for retroviral or lentiviral transduction significantly increases transduction efficiency and results in enhanced gene transfer, especially in suspension and hematopoietic stem cells. RetroNectin Reagent is a chimeric peptide composed of E. coli-derived recombinant human fibronectin fragment that contains three funct…
Mouse ROSA26 safe harbor gene knock-in kit and clones. ROSA26 (also known as ROSAβgeo26 locus) in mice genome is first found in chromosome 6 in one particular strain of mice-named ROSAβgeo26-expressed β galactosidase from a randomly inserted transgene at high levels uniformly in nearly all tissues examined. This locus expresses one coding transcript and two noncoding transcripts, and only the non-coding transcripts are disrup…
GeneCopoeia offers complete custom services for CRISPR-Cas9-based targeted genomic modification, including CRISPR design and construction, donor design and construction, functional validations, stable cell line establishment, and transgenic mouse generation. Service Details: Validation Services Donor clone services Stable cell line services Transgenic mouse services Advantages: Fast delivery of CRISPR-Cas9 plasmids…
The SureSelect Focused Exome is a highly targeted design that enables analysis of only disease-associated targets, enabling superior coverage of disease-associated regions even on benchtop sequencers. This design provides 20 or more reads for 95% of targets at 1.5Gb (100x) of sequencing and 98% of targets with 3Gb (200x) of sequencing.
The MWave-5000 multifunctional microwave is truly a robust system. The 5000 Integrates microwave synthesis, distillation,concentration, pressurized or non-pressurized reaction, and low temperature microwave reaction into one system. Features: The 5000 has three modes of reaction, under pressure, Normal pressure, and decompressed. Three different sample vessel volumes 300ml, 500ml, and 1 Liter. Variable magnetron outp…
The Sci-Print MP2 is a benchtop semi-automated barcode label printer that prints and applies labels onto a variety of microplates* for sample tracking. It can be used in a manual stand-alone environment or integrated into a fully automated system.
The ChIPettor™ System has everything you need for high-quality, fast, and easy chromatin immunoprecipitation for either histones or transcription factor ChIP. Contains a full set of reagents for start-to-finish ChIP starting with 100,000 to 1,000,000 cells (ideal for histone pull down), purification reagents, and a semi-automated pipettor with special resin pipet tips. The ChIPettor™ is designed to stand independently on a 9…
Hamilton Robotics and Coastal Genomics have partnered to combine the NIMBUS platform with Ranger® Technology. The new NIMBUS Select workstation is the first option to fully automate size selection and analysis of nucleic acids using high throughput agarose gel electrophoresis. Scientists can now leverage high resolution fractionation for sample preparation and quality control in a fully automated, high throughput fashion.Bene…
SMART (Switching Mechanism at 5’ End of RNA Template) is a unique technology that allows the efficient incorporation of known sequences at both ends of cDNA during first strand synthesis, without adaptor ligation. The presence of these known sequences is crucial for a number of downstream applications including amplification, RACE, and library construction. While a wide variety of technologies can be employed to take advantag…
