Proteomics is the systemic bioinformatics study of proteins and amino acids, including their structure, size, function and identification. Tools used in proteomics include chromatography, blotting and gels, protein arrays, mass spectrometry and ELISA and associated analysis software. Analyzers and proteomic systems should be sensitive, high resolution, fast and may be automated for high-throughput.
Benzonase Nuclease - Effective viscosity reduction and removal of nucleic acids from protein solutions Benzonase Nuclease is a genetically engineered endonuclease from Serratia marcescens. It degrades all forms of DNA and RNA (single stranded, double stranded, linear and circular) while having no proteolytic activity. Benzonase Nuclease is effective over a wide range of conditions and possesses an exceptionally high specif…
An easy way to assess tag accessibilityThe production of fusion proteins often raises the issues not only of their structural integrity after isolation, but also of the accessibility of the associated tag. In the case of GST or 6HIS tagged proteins, this verification can be achieved with HTRF® GST and 6HIS check kits. These two assays are competitive immunoassays in which the anti-GST or anti-6HIS Cryptate conjugates bind dire…
Rapid Analysis of Multiple 2D Gel Sets DYMENSION 2 has all the features of DYMENSION 1 but has the added ability to detect and compare protein spot maps in multiple gel sets. The software offers many background correction and noise filtering features including a SYPRO® Ruby filter, which can detect and automatically remove spots caused by SYPRO® Ruby crystals adhering to the gel, thus saving users valuable time editing the…
Quick and Easy Analysis of all 2D Gel Applications The exciting DYMENSION 3 software has all the functionality of DYMENSION 2, so can be used to analyse multiple gel sets. In addition, DYMENSION 3 is capable of analysing multi-stained fluorescent gel images stained with up to three contrasting fluorescent labels, for example, Cy™2, Cy™3 and Cy™5. This feature allows users to analyse multiple sets of any type of 2D protein…
Fluorescence Protein Detection Test ProReveal is a highly sensitive fluorescence-based patented protein detection test for checking the presence of residual protein on surgical instruments after going through a washer disinfector process. This cost-effective test (conforms to BS EN ISO 15883-1) delivers objective, visual and measurable results, removing any doubt as to whether a decontaminated instrument is safe for reuse. Ke…
The MultiPep RSi is a fully automated high throughput multiple peptide synthesizer based on a pipetting robot. Utilizing exchangeable modules, the MultiPep RSi can be configured to enable the synthesis of small scale peptide libraries, membrane bound peptide arrays (SPOT method), specialty peptides or PNAs, as well as high quality peptides in large scales up to 10 mmol. Due to this flexibility, the instrument can take the pl…
The MultiPep CF is a fully automated peptide synthesizer with a unique column module that allows the synthesis of long and difficult sequences. During the synthesis, reagents are continuously circulated and real time UV monitoring enables the automatic optimization of reaction parameters like deprotection, coupling times, and wash steps. This leads to a greater coupling yield, superior peptides, and also saves time and reduc…
GFP/RFP-Booster – enhance your fluorescent fusion protein ChromoTek’s Booster are very small, highly specific GFP- or RFP-binding proteins covalently coupled to the superior fluorescent dyes from ATTO-TEC. With our Booster you can: • Reactivate • Boost • Stabilize the signals of your fusion proteinsDirectly stain your protein of interest in fixed cells and benefit from the high specificity an small size that are perfect for su…
Chromobodies® - Your perfect reagents for cellular research including High-Content Analysis. Chromobodies are fluorescent nanoprobes suitable for real time analyses of endogenous cellular structures and processes in live cells. Chromobodies® are a novel species of extremely small intracellular antibodies. They are based on the antigen binding domain (VHH) derived from heavy chain antibodies of camelids genetically fused to a f…
DNA methylation was the first epigenetic modification identified and has been intensively studied for more than half a century. By now it is clear that Dnmt1, the major eukaryotic DNA methyltransferase, faithfully maintains genome-wide methylation patterns and plays an essential role in the epigenetic network controlling gene expression and genome stability during development. However, the molecular mechanisms that ultimately…
Proliferating cell nuclear antigen (PCNA) is a homotrimeric ring-shaped protein that encircles DNA and acts as a loading platform for multiple, transiently interacting factors participating in various DNA transactions. PCNA plays a key role in DNA replication, repair, cell cycle regulation, and post-replicative transactions like DNA methylation and chromatin remodeling. All these cellular processes are regulated by a complex n…
The SIRTainty™ Class III HDAC Assay utilizes a novel patent pending technology for the sensitive detection of all known sirtuin family members. This easy to perform assay employs nicotinamidase to measure nicotinamide generated upon cleavage of NAD+ during sirtuin mediated deacetylation of a substrate providing a direct assessment of the activity of class III HDAC enzymes. Unlike conventional assays that are dependent upon a s…
The IEF100 is the only first dimension instrument that controls the current and voltage applied to the IPG strips to prevent overheating. It has flexible first-dimension IEF can be run with up to six 7 to 24 cm IPG strips simultaneously, or twelve 7 cm IPG strips using the included dual electrode accessory. The unit has turn and click intuitive user interface with graphical display, and is capable of faster run times with an i…
Combines the advantages of small format and efficient cooling for rapid screening of proteins and nucleic acids. The Hoefer™ SE260 small format vertical slab gel unit is intended for rapid electrophoresis of protein or nucleic acid samples. Most samples can be run in as little as 45 minutes, and only a minimal amount of sample is required.SE260 Deluxe Mighty Small Mini Vertical Unit Features: Maximum glass plate size 10 x…
Taller format accommodates 24 cm long gels for increased resolution. The Hoefer® SE600 series vertical slab gel electrophoresis units are intended for protein and nucleic acid electrophoresis under commonly used denaturing and non-denaturing conditions. Up to 28 samples can be compared on a single slab gel.SE660 Tall Standard Dual Cooled Vertical Unit Features: Maximum glass plate size 18 x 24 cm Produce straight lanes a…
Ergonomic design offers easier handling and sample introduction. The Hoefer® SE600 Chroma vertical slab gel electrophoresis unit is intended for protein and nucleic acid electrophoresis under commonly used denaturing and non-denaturing conditions. Up to 28 samples can be compared on a single slab gel.SE600X Dual Cooled Vertical Units Features: Maximum glass plate size 18 x 16 cm Gels are fully submerged for greater temp…
Hoefer pioneered the vertical format for electrophoresis separations. The Hoefer® SE600 series vertical slab gel electrophoresis units are intended for protein and nucleic acid electrophoresis under commonly used denaturing and non-denaturing conditions. Up to 28 samples can be compared on a single slab gel.SE600 Wide-Mini Vertical Unit Features: Maximum glass plate size 18 x 16 cm Produce straight lanes and sharp, well…
Compact, rugged, and economical units ideal for educational laboratories with multiple users. The Hoefer® SE400 and SE410 Sturdier™ Vertical Slab Gel Electrophoresis Units are intended for electrophoretic separation of proteins and nucleic acids under both denaturing and native conditions. Up to 28 samples can be compared on a single slab gel.SE410 Tall Air-Cooled Vertical Unit Features: Maximum glass plate size 18 x 24 c…
Compact, rugged, and economical units ideal for educational laboratories with multiple users. The Hoefer® SE400 Vertical Slab Gel Electrophoresis Units are intended for electrophoretic separation of proteins and nucleic acids under both denaturing and native conditions. Up to 28 samples can be compared on a single slab gel.SE400 Standard Air-Cooled Vertical Unit Features: Maximum glass plate size 18 x 16 cm The rugged i…
Designed for quick screening and rapid separation. The Hoefer™ SE250 small format vertical slab gel unit is intended for rapid electrophoresis of protein or nucleic acid samples. Most samples can be run in as little as 45 minutes, and only a minimal amount of sample is required.SE250 Mighty Small Mini Vertical Unit Features: Maximum glass plate size 10 x 8 cm Efficient active cooling ensures sharp bands Quick and easy…
Ideal for routine preparatory and analytical electrophoresis techniques. The SUB6 Mini Horizontal Gel Unit has a maximum 32-sample throughput capacity and features a removable gel-casting tray with end gaskets that allow gels to be cast directly within the tank. SUB6 Mini Submarine Unit Features: Color-coded and height adjustable combs-easily identify comb thickness at a glance and control well depth Colored loading str…
The TV100 and TV100K twin-plate 10 x 10cm (W x H) mini-gel units are ideal cost-effective solutions for standard PAGE applications, using self-cast or commercially available precast gels. As the standard unit of the twin-plate mini-gel format, the TV100 is the most cost-effective option. TV100 Series Cooled Tin-Plate Mini-Gel Electrophoresis Vertical Units Features: Twin-plate 10 x 10cm mini-gel unit - a simple cost-effec…
The TV400 and TV400K twin-plate 20.5 x 20cm (W x H) maxi-gel units offer all the benefits of the TV100 and TV200 units, but in a much larger gel size and with increased sample throughput. A cooling coil within the TV400K gel tank allows faster separations to be performed at high voltage without compromising resolution.TV400 Standard & TV400K Cooled Twin-Plate Maxi-Gel Electrophoresis Units Features: Twin-plate 20.5 x 20cm…
The TV400Y and TV400YK twin-plate 20.5 x 20cm (W x H) maxi-gel units offers all the benefits of the TV100 and TV200 units, but in a much larger gel size and with increased sample throughput. Both units include, as standard, a precision engineered casting base, which acts in tandem with our recently modified TV400-GRM to provide simple, leak-free casting. TV400Y Standard & TV400YK Cooled Twin-Plate Maxi-Gel Electrophoresis Uni…
ProteinCenter™ is a web-based data interpretation tool that enables scientists to compare and interpret data sets in minutes instead of months ProteinCenter is a web-based tool that enables scientists to compare and interpret proteomics data sets in minutes and overcomes the hurdle of proteins existing under different names and accession keys in different databases. Regularly updated from all major protein databases, ProteinC…
