High performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.
OPTI-SEAL® Piston/Plunger Seals are the longest lasting seals on the market. Machined from either of two proprietary polymer blends, UHMW-PE or ITB, Optimize Seals provide the ultimate in high pressure sealing capacity. For mostly aqueous buffered mobile phases, OPTI-SEAL® UHMW-polyethylene is the wisest choice. Specially designed to be more resistant to abrasion and wear than standard polyethylene seals, they can last up to s…
Optimize realizes that your time is valuable and should not be wasted worrying about fittings. For this reason, all Opti-Lock Fittings are precision machined in the USA for optimal quality and thread consistency. The machining process is the best way to ensure tight manufacturing tolerances and minimal product variance. What does all this mean? It means that every fitting you purchase from Optimize will perform just as well as…
Optimize Back Pressure Regulators utilize an active mechanism to maintain steady back pressure across a range of mobile phase viscosities and flow rates. Placing one downstream from your detector will prevent solvent decompression and bubble formation in the flow cell, reducing baseline noise and drift. Each pre-set Optimize stainless steel Back Pressure Regulator offers a 100µL internal volume and includes fittings for immedi…
Optimize Replacement Pistons/Plungers are, by design, a consumable part of the HPLC pump and should be replaced on a regular preventative maintenance schedule. To maintain peak performance and avoid unplanned downtime, sapphire pistons require inspection every six months with yearly or as-needed replacement. Optimize sapphire pistons offer optimal concentricity and resistance to wear. Each sapphire rod is specifically cut in r…
The OPTI-LYNX™ Quick Connect Filters allow you to connect any 10-32 valve/port for trapping or analytical column for pre-column filtration. With OPTI-LYNX™, accessing and changing the insert takes only a quarter turn. Replace traps, filters or change configurations in seconds, without tools. OPTI-LYNX™ traps and filters (ordered separately) come in several bed volume/ diameter/ porosity combinations, allowing you to find your…
The OPTI-LYNX™ Quick Connect Trap Columns allow you to quick-connect to any 10-32 valve/port for trapping or analytical column for pre-column filtration. With OPTI-LYNX™, accessing and changing the insert takes only a quarter turn. Replace traps, filters or change configurations in seconds, without tools. OPTI-LYNX™ traps and filters (ordered separately) come in several bed volume/ diameter/ porosity combinations, allowing you…
The OPTI-LYNX™ QuickConnect Guard Column is a high-performance, cartridge-based guard system, suitable for use with any 10-32 analytical column due to its auto-adjusting ZDV port adapter. OPTI-LYNX™ combines effective column protection with the convenience of quick-connect operation. Some cartridge-based guard column products offer convenience with a price: higher internal volumes. Optimize Technologies, refuse to compromise p…
The LaChromUltra® U-HPLC System, in combination with the TQ Detector, provides unmatched quantitative analysis and characterization capabilities. Features • Seamless integration of the U-HPLC system and the TQ Detector with Empower™ 2 control • Performs SIR, MRM, Product, Precursor, and Neutral Loss Scans on the U-HPLC timescale • Equipped with dual ESI/APCI source as standard, with optional APPI available • 20 ms polarity swi…
The Hitachi HPLC Primaide is designed for long-term, stable operation, and features both high reliability and great durability. It offers tremendous capability for everyday analysis.Based on over 50 years of experience in the development and production of HPLC systems, Hitachi proudly introduces the Primaide. Make the most of your analytical equipment with Hitachi as the “Prime Aide” in your lab! Modules • Primaide 1110 Pump w…
This new zwitterionic stationary phase with phosphorylcholine functional group provides you with complementary selectivity for easier method development for substances that have been difficult to separate by previous types of HPLC columns operated in reversed-phase or HILIC mode. The selectivity features of SeQuant® ZIC®-cHILIC are especially beneficial for negatively charged polar compounds such as nucleotides and organic…
LyoSpeed™ delivers exceptional results with even the most difficult samples. When working with certain solvents, e.g. HPLC solvents, a fully dried result can be hard to achieve due to interactions with the dissolved sample - resulting in the formation of a gum or oil.In response to customer demand Genevac have developed a Fast Lyophilisation, or LyoSpeed™ process to resolve these problems for customers working with HPLC solve…
Fast separation of pharma samples: 10 compounds in 2 minutes. As in all industries, greater productivity has become increasingly important in the field of pharmaceuticals. Consequently, there is a growing demand for fast and ultra-fast separations as well as higher sample throughput. To answer these requirements, Merck Millipore offers the perfect combination for separation speed and peak symmetry: Purospher® STAR UHPL…
Polymer bulk packing material for anion exchange applications.
Chromabolt™ is a family of pre-validated columns prepacked with EMD Millipore chromatography resins, designed for early clinical stage manufacturing. Available in 3 sizes – 10, 20 and 32 cm inner diameter (i.d.), these prepacked columns free up end users valuable time and resources by eliminating manual packing and cleaning. With Chromabolt™ prepacked columns, you can spend your time on manufacturing your products and not on…
Eshmuno® A is a rigid, high capacity Protein A affinity chromatography resin for the purification of Fc-containing proteins, including but not limited to monoclonal antibodies. Eshmuno® A resin can be cleaned and sanitized under acid and alkaline conditions while maintaining high dynamic binding capacity at high flow rates.The Eshmuno® A resin contains a EMD Millipore proprietary ligand. This ligand is recombinantely expresse…
The PDS-100 is a Programmable Dispensing System which uses precision stepper motors to control FMI “Q” and “RH” pump models including STQP, STQ, STH, & STRH in all piston sizes. The FMI pumps are integrally mounted to the programmable controller. The controller contains the stepper motors and driver electronics, and is a rugged anodized aluminum design. Several single and dual pump configurations are available including a dua…
PiP Pumps micro π-petter - Pipetting, Syringing and Diluting Ideal for repetitive and volumetric dispensing of acids, solvents and aqueous solutions. Model "PiP" Precision Dilutor Features: FMI's unique low dead-volume pump heads, and synchronous motor drives. Can act as a single shot dispenser using the hand/foot switch or as a single metering pump in the continuous mode. Using a combination of forwar…
Ideal for Analyzers, Environmental Sampling & Injection, & Low Current Remote Battery Operation Model QBG Low Current DC Features: Ideal for extended 12/24 volt battery operation in remote locations. They are rated 60 RPM at 12 VDC and 120 RPM at 24 VDC. One Moving Part - NO VALVES! Low Current DC Operation Self Priming Patented CeramPump® Design
With a choice of over 40 different phases (and we continue to develop additional, unique and powerful HPLC sorbents) our SiliaChrom series of HPLC columns surely has the reversed or normal phase you need for your application.Mostly made from a silica-based sorbent, we carefully monitor the manufacturing process, from raw material synthesis to packing, ensuring you that our HPLC columns are of the highest quality.All columns ar…
For two decades, SiliCycle has been dedicated to silica gel manufacturing and has achieved a strong know-how and recognized expertise in this field. Furthermore, to support the increasing demand of our spherical silica gels, we have developed and optimized a highly controlled, large-scale, production process for all our SiliaSphere products, without compromising silica quality. SiliaSphere silica gels are manufactured from a…
The Thermo Scientific™ Acclaim™ Trinity™ P2 column is a high-performance, silica-based column specifically designed for separation of pharmaceutical mono- and multi-valent counterions by high-performance liquid chromatography (HPLC). This column was engineered for analytical chemists who need simple, robust, fast, generic methods. The Acclaim Trinity P2 columns provide an effective solution for counterion analysis using one co…
SpeedCore is the very latest in core-shell technology for use in HPLC and UHPLC. Designed to offer enhanced efficiency, speed and resolution of analysis. Speedcore C18 is designed to provide characteristics which will enhance method development. It provides the ability to obtain sharp peak shapes whilst retaining and separating a wide variety of compounds both hydrophobic and hydrophilic.SpeedCore C18 Features: C18 Hydroph…
HT4000L is an HPLC autosampler for high presise injection into HPLC, UHPLC, LC/MS and IC systems. HT4000L is lab automation ready. In fact HT4000L besides working as a standard HPLC autosampler, can take care of many sample preparation tasks as no standard autosampler has been able to assist up to now. Basic sample preparation capabilities includes dilution, precolumn derivatization, pH spiking and internal standard addition…
HT310L is a cost-effective HPLC autosampler, that offers automation for processing up to 10 unattended samples. By its competitive pricing is the alternative to the manual injector for users that cares about reproducibility and accuracy. HT310L fits every HPLC system, and its direct syringe injection minimizes dead volume, reduces carry-over and improves repeatability. Full and partial loop are both performed with very accura…
