In-Situ Hybridization Products & Reviews

TOP2A IQFISH pharmDx™ is a direct fluorescence in situ hybridization (FISH) assay based on Dako's new fast IQISH hybridization buffer chemistry. The new IQISH hybridization buffer is non-toxic and allows genomic DNA probe hybridization to be performed in just 60-120 minutes. The short hybridization time results in a turnaround time of about 3½ hours for a complete FISH staining from deparaffinization to mounting. TOP2A IQFISH…

The UVP Hybridizer Oven provides uniform temperature and rotation controls for thorough mixing of materials.  

The UVP Hybrilinker Oven is a self-contained unit which provides the unique combination of a hybridization oven and a 254 nm ultraviolet crosslinker.  

For labs that require high throughput and automated RNA in situ hybridization (ISH) analysis, ACD has partnered with Leica Biosystems and Roche Tissue Diagnostics to deliver RNAscope ISH automated assays.

The BaseScope™ Assay is a unique product from ACD, based on the same platform of proven and established RNAscope™ technology that has been cited in over 2300 publications. This powerful assay provides new data dimensions and unique insight into biological mechanisms. The BaseScope™ Assay enables applications such as the detection of exon junctions/splice variants, short/highly homologous RNA sequences (50-300 bases), and poin…

The RNAscope™ and BaseScope™ Assays are based on the proprietary RNAscope Technology enabling RNA target expression analysis within intact cells and tissues with high sensitivity and specificity. Using proprietary ACD RNAscope Probe Design Pipeline, we provide double "Z" oligo probes designed to hybridize to your specific RNA target of interest.

Introducing RNAscope HiPlex assay to expand your in situ hybridization potential.

CHEMICON's Sure Blot® CHEMI™ Hybridization & Detection Kit is designed to provide high quality, non-radioactive detection of digoxigenin-labeled DNA probes hybridized to Sure Blot® Nylon Membrane. As an integrated hybridization and detection system, Sure Blot® CHEMI™ is quality controlled to produce high signal and low background. Comparable sensitivity to 32P is typically observed for single-copy gene detection. Sufficient re…

Hybrisol® Hybridization Solutions are pre-made, ready-to-use solutions optimized for sensitive single and multiple gene copy detection using membrane-based hybridization techniques. They are designed to give maximum signal and clean background for hybridizations performed on nylon and nitrocellulose membranes. Hybrisol® Solution contains 10% Dextran Sulfate, 1% SDS, 50% Formamide, 6X SSC, Sheared DNA, and Modified Denhardt's S…

SmartFlare Probes work by recognizing specific native RNA sequences within living cells, therefore there are many possible sequences that you could design to recognize your target of interest. Instead of lysed cells, switch to live cells. And while you’re at it, eliminate sample preparation and transfection steps all together. Live cell RNA detection is now possible, in a single incubation step using inert nanoparticle techno…

The labelling of DNA samples used in array comparative genomic hybridisation (aCGH) is a critical step in the experimental process as poor labelling can result in inaccurate data. OGT’s CytoSure Genomic DNA Labelling Kits have been uniquely developed and optimised to enable rapid delivery of high quality results with high signal-to-noise ratios.

Double-quenched probes that offer improved quenching over longer probe sequences

COT I Human DNA is prepared from human male placenta DNA and is used for background reduction in applications like Microarrays and In Situ Hybridisations

Compact Research Stainer

High quality, reliable and easy-to-use DNA probes for fluorescence in situ hybridisation (FISH)

High quality, reliable and easy-to-use DNA probes for fluorescence in situ hybridisation (FISH)

CytoCell myProbes® is a custom design and manufacture service that provides unique fluorescence in situ hybridisation (FISH) probes using the BAC-2-FISH™ process.

IVDR certified probes now available!

An integrated solution for drug target identification with the next generation Fluorescent Differential Display System. mRNA Differential Display technology (DD) developed by Liang and Pardee is a powerful tool for identifying and cloning differentially expressed genes. The RNAspectra™ Kits, based on GenHunter technology, feature a new generation of DD technology using fluorescent labeled PCR products (FDD) instead of radioa…

Thermo's hybridisation bottles are manufactured using thick walled boro-silicate glass which absorbes over 90% of ß-emissions ensuring safe and easy handling.  Every oven is supplied with a bottle gripper free of charge.  The rubber sleeve increases user safety by protecting the user from burns as well as giving a better grip during manipulations. An optional mesh system for easy membrane handling is also available. Product d…