Genomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.
As our latest generation of RNA library preparation kits, KAPA RNA HyperPrep Kits utilize a novel chemistry and combines enzymatic steps to achieve fewer reaction purifications and yield high-quality RNA-seq libraries in a single day. They also offer flexible workflow options that include the enrichment of desired transcripts by selective mRNA capture or rRNA depletion.
Efficient, and uniform hybridization-based capture for Whole Exome Sequencing Combining more than a decade of probe-design experience with an improved probe-manufacturing process, the new KAPA HyperExome probe pools enable efficient, uniform hybridization-based capture for Whole Exome Sequencing (WES).
KAPA HyperPETE (Primer Extension Target Enrichment) is a novel hybridization capture technology designed to employ primer extension reactions to specifically capture and release target library molecules for sequencing.
KAPA EvoPlus V2 Kits is an enhanced enzymatic DNA library preparation solution that features improved fragmentation performance, insensitivity to inhibitors, increased conversion efficiency & fewer sequencing artifacts.
Achieve high-performing NGS library preparation from mechanically fragmented DNA or cell-free DNA (cfDNA) in a streamlined, automation-friendly workflow with KAPA EvoPrep Kit. The KAPA EvoPrep workflow reduces pipetting and reagent preparation steps and is validated with challenging sample inputs such as cfDNA and FFPET DNA.
SignalChem(part of Sino Biological) offers one of the most comprehensive ranges of biologically active recombinant enzymes as well as a broad range of high-quality, low-cost enzyme activators and inhibitors of different classes of enzymes including protein kinases, phosphatases, and epigenetic enzymes.
KAPA HiFi DNA Polymerase is a novel, single-enzyme system that exhibits industry-leading performance when compared with other high-fidelity polymerases and polymerase blends.
SignalChem (Part of Sino Biological) offers tailored contract research services ranging from enzyme development and compound profiling to assay development.
The HU6 Mini horizontal gel unit is ideal for routine preparatory and analytical electrophoresis techniques. It has a maximum 32-sample throughput capacity and features a removable gel-casting tray with end gaskets that allow gels to be cast directly within the tank. The gel-casting tray is simply turned at 90° to the direction of electrophoresis, when the end gaskets form a leak proof seal against the inner walls of the runn…
The HU20 Maxi-standard horizontal gel unit is ideal for large-scale preparatory and analytical electrophoresis techniques.A 20 x 20cm gel-casting tray, with 4 comb positions, allows the user to perform high-resolution analytical research for a maximum of 168 samples, while buffer recirculation ports are included as standard to prevent buffer depletion and ion gradient formation during long-distance separations. Casting gates w…
The HU25 Maxi-Plus standard horizontal gel unit is designed specifically for high throughput screening of nucleic acids, particularly PCR products and in genotyping studies.A 25 x 30cm gel-casting tray, with 12 positions for multichannel-compatible combs, accommodates a maximum throughput of 624 samples. Buffer recirculation ports are included as standard to prevent buffer depletion and ion gradient formation during long-dista…
The HU10 mini-plus horizontal gel electrophoresis unit is ideal for routine preparatory and analytical electrophoresis techniques. It has a maximum 80-sample throughput capacity and features a removable gel-casting tray with end gaskets that allow gels to be cast directly within the tank. The gel-casting tray is simply turned at 90° to the direction of electrophoresis, when the end gaskets form a leak proof seal against the i…
Syngene GeneTools - Advanced 1D gel analysis Syngene GeneTools is an advanced 1D gel and 2D spot blot analysis software for use with any gel documentation system. The Syngene GeneTools highly automated software can rapidly analyse a gel from loading an image to output of results in a matter of seconds. With an extensive and flexible array of options you can handle a range of media including gels, plates, films and blots,…
The CpG WIZ® p16 Amplification Kit is used for determining the methylation status of the p16 promoter by methylation-specific PCR (MSP). The kit contains primers targeted to regions of the promoter where the sequences are most divergent after bisulfite treatment. PCR parameters have been identified such that all primer sets in the kit amplify under the same conditions. Control genomic DNA samples (methylated and unmethylated)…
The CpG WIZ® p15 Amplification Kit is used for determining the methylation status of the p15 promoter by methylation-specific PCR (MSP). The kit contains primers targeted to regions of the p15 promoter where the sequences are most divergent after bisulfite treatment. PCR parameters have been identified so that all primer sets in the kit amplify template under the same conditions. Control genomic DNA samples (methylated and unm…
The CpG WIZ® E-cahedrin Amplification Kit is used for determining the methylation of status of the E-cadherin promoter by methylation-specific PCR (MSP). The kit contains primers targeted to regions of the promoter where the sequences are most divergent after bisulfite treatment. PCR parameters have been identified so that all primer sets in the kit amplify under the same conditions. Control genomic DNA samples (methylated and…
The CpG WIZ® Prader-Willi/Angelman Amplification Kit is used for determining the methylation status of this region by methylation -specific PCR (MSP). The kit contains primers targeted to the CpG island on the SNRPN gene. PCR parameters have been identified such that both primer sets in the kit amplify template under the same conditions. Normal control genomic DNA, which will generate a product with both primer sets, is also i…
The CpGenome™ DNA Modification Kit is used to create methylation-specific sequence alterations in any DNA sample. Using chemical treatment, the kit converts all unmethylated cytosine residues to uracil. Methylated cytosine residues are unaltered in this process. Therefore, the chemically-treated DNA sequence will differ only if it was originally unmethylated in vivo. After sequence conversion, methylation specific PCR is emplo…
CpGenome™ Universal Methylated DNA is enzymatically methylated human male genomic DNA. This product is intended for use with the CpGenome™ DNA Modification Kit (S7820) or with amplification primers. It can be used as a methylation-positive control for gene methylation studies.
CpGenome™ Universal Unmethylated DNA Set provides 2 separate genomic DNA controls for gene methylation studies. This product is intended for use with the CpGenome™ DNA Modification Kit (S7820) and can be subsequently used as an unmethylated DNA control for gene methylation studies.
The CpGenome™ Fast DNA Modification Kit contains the reagents for the initial bisulfite modification of the DNA required for both methodologies.
The CpGenome™ DNA Modification Kit (Cat. No. S7820) contains the reagents necessary to perform the initial bisulfite reactions, while the CpG WIZ® BRCA1 Amplification Kit contains the reagents required for the PCR amplification reactions.
ChIP-Seq facilitates genome-wide profiling of the interactions of transcription factors, modified histones, and other chromatin associated proteins. By combining chromatin immunoprecipitation with next generation sequencing, laboratories can generate high resolution data on protein-DNA interactions across the genome. For laboratories interested in gaining a deeper understanding of epigenetic mechanisms of gene regulation, ChIP…
Superior Bead Recovery and Low Levels of False Positives Ensure Assay Reproducibility. Smooth well wall provides efficient bead recovery, ensuring reproducible results lot after lot High performance membrane does not trap microspheres in the membrane matrix In serological assays, Supor® membrane effectively removes IgG complexes, thus reducing nonspecific reactivity of the microspheres and reducing false positives New well des…
