UHPLC and HPLC Products & Reviews

High performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.

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Thermo Scientific™ MAbPac™

Thermo Fisher Scientific

Use the new Thermo Scientific™ MAbPac™ RP columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins. These columns have excellent resolution, long column lifetime, and low carry-over.

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Thermo Scientific™ Vanquish™ Charged Aerosol Detector F

Thermo Fisher Scientific

Utilize the increased separation speed and resolution of the Thermo Scientific™ Vanquish™ UHPLC system to detect and quantify virtually any substance using the near-universal detection capabilities of Vanquish Charged Aerosol Detectors. Ideal for everyday analyses, the Thermo Scientific™ Vanquish™ Charged Aerosol Detector F offers enhanced linear dynamic range and accurate, consistent response. This detector can measure low-le…

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Thermo Scientific™ Vanquish™ Split Sampler F

Thermo Fisher Scientific

Combine maximum injection precision and huge sample capacity. The Thermo Scientific™ Vanquish™ Split Samplers employ high-throughput performance for the highest confidence in peak identification and quantitation possible. The samplers provide fully biocompatible fluidics, unsurpassed sample dosing precision, and is optimized for ruggedness and uptime, even under the toughest system pressure of up to 1500 bar (22,000 psi) and c…

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Thermo Scientific™ Vanquish™ Split Sampler H

Thermo Fisher Scientific

Combine maximum injection precision and huge sample capacity. The Thermo Scientific™ Vanquish™ Split Samplers employ high-throughput performance for the highest confidence in peak identification and quantitation possible. The samplers provide fully biocompatible fluidics, unsurpassed sample dosing precision, and is optimized for ruggedness and uptime, even under the toughest system pressure of up to 1500 bar (22,000 psi) and c…

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Thermo Scientific™ Vanquish™ Dual Split Sampler F

Thermo Fisher Scientific

Improve productivity using the Thermo Scientific™ Vanquish™ Dual Split Sampler F. Designed to support Thermo Scientific™ Vanquish™ Duo UHPLC system for Dual LC, this unique biocompatible autosampler with 1000 bar pressure, the Vanquish Dual Split Sample F combines two injection devices in one housing, resulting in two separate channels that are individually controllable (injector volume, wash cycles, etc.).

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Thermo Scientific™ Vanquish™ Dual Split Sampler H

Thermo Fisher Scientific

Improve productivity using the Thermo Scientific™ Vanquish™ Dual Split Sampler H. Designed to support Thermo Scientific™ Vanquish™ Duo UHPLC system for Dual LC, this unique biocompatible autosampler with 1500 bar pressure, the Vanquish Dual Split Sample F combines two injection devices in one housing, resulting in two separate channels that are individually controllable (injector volume, wash cycles, etc.).

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Thermo Scientific™ Vanquish™ Charger Module

Thermo Fisher Scientific

Employ an intelligent robotic that is fully integrated into a Thermo Scientific™ Vanquish™ UHPLC system with the Vanquish Charger module. With a capacity of 8832 samples (23 well plates), the Charger module automates sample loading into the Vanquish system for extra-long unattended operation. Environmental controls ensure reliable sample protection. A barcode reader automatically inventories each plate or rack within the devic…

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Thermo Scientific™ UltiMate™ ACC-3000 Autosampler Column Compartments

Thermo Fisher Scientific

Reduce the size and cost of your liquid chromatography (LC) system. The Thermo Scientific™ UltiMate™ ACC-3000 Autosampler Column Compartments provides a cost-effective solution for conventional LC and UHPLC applications at up to 62MPa (9000 psi) operating pressure. It integrates an autosampler and column compartment (with optional sample thermostatting) in a single module and offers performance and flexibility that exceed mos…

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Thermo Scientific™ UltiMate™ WPS-3000TFC/TBFC Well Plate Autosampler with Fraction Collector

Thermo Fisher Scientific

Simplify off-line multidimensional and multistep liquid chromatography (LC) in analytical and micro flow rate ranges. The Thermo Scientific™ UltiMate™ Autosampler with Fraction Collector uniquely supports both sample injection, fractionation, and reinjection using two integrated switching valves. The instrument fully automates multidimensional separations, allowing columns that differ in chemistry and internal diameter to be c…

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Thermo Scientific™ UltiMate™ WPS-3000TBRS Biocompatible Rapid Separation Well Plate Autosampler

Thermo Fisher Scientific

Extend your biocompatible flow path for sensitive analyses. The Thermo Scientific™ Dionex™ UltiMate™ WPS-3000TBRS Biocompatible Rapid Separation Well Plate Autosampler protects your samples from start to finish with a ceramic needle, titanium injection valve and biocompatible fingertight fittings. This UHPLC autosampler uniquely injects up to 500µL at pressures up to 15,000 psi (103.4 MPa). The in-line split-loop (or flow-thro…

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